Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Svetoslav Slavov"'
Publikováno v:
Letters in Drug Design & Discovery. 20:1757-1767
Background: A large scale experimental validation conducted at the National Center for Advancing Translational Sciences (NCATS/NIH, USA) confirmed the predictions of our 3D-SDAR model of hERG blockage and phospholipidosis induction. It was demonstrat
Autor:
Svetoslav Slavov, Alessandra Matsuno, Aparecida Yamamoto, Katia Otaguiri, Maria Cervi, Dimas Covas, Simone Kashima
Publikováno v:
Pediatric Reports, Vol 9, Iss 4 (2018)
Zika virus (ZIKV) is a mosquito-borne flavivirus, which has been related to severe neurological complications in neonates. However, many clinical aspects of the infection remain unclear, especially in pediatric patients. In this case report we descri
Externí odkaz:
https://doaj.org/article/d96a7925a41e464fafb62fc65b93d54b
Autor:
Jinchun Sun, Svetoslav Slavov, Laura K. Schnackenberg, Yosuke Ando, James Greenhaw, Xi Yang, William Salminen, Donna L. Mendrick, Richard Beger
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 10, Iss 17, Pp 78-89 (2014)
It has been estimated that 10% of acute liver failure is due to “idiosyncratic hepatotoxicity”. The inability to identify such compounds with classical preclinical markers of hepatotoxicity has driven the need to discover a mechanism-based biomar
Externí odkaz:
https://doaj.org/article/4e03397c671e4b369fbec5f88f2ece24
Autor:
Svetoslav Slavov, Richard D. Beger
Publikováno v:
Current Opinion in Toxicology. :46-49
During the past decade, quantitative structure–activity relationship (QSAR) enjoyed an ever-increasing application in various fields including translational sciences. This review summarizes the progress in data preprocessing, processing, and valida
Autor:
Yeh-Hyon Cho, Hong Xing, Jon M. Lindstrom, Ron J. Lukas, Anne Rouchaud, Kristin W. Andrud, Svetoslav Slavov, Ziang Lu, James R. Rocca, William R. Kem, Stephan C. Jahn, Ferenc Soti, Patrick Corsino, Sophia Habibi
Publikováno v:
Molecular Pharmacology. 98:168-180
The two major nicotinic acetylcholine receptors (nAChRs) in the brain are the α4β2 and α7 subtypes. A "methyl scan" of the pyrrolidinium ring was used to detect differences in nicotine's interactions with these two receptors. Each methylnicotine w
Publikováno v:
Archives of Toxicology. 94:1215-1227
Addiction is a complex behavioral phenomenon in which naturally occurring or synthetic chemicals modulate the response of the reward system through their binding to a variety of neuroreceptors, resulting in compulsive substance-seeking and use despit
Autor:
Jéssika Lesbon, Mirele Poleti, Elisângela de Mattos Oliveira, José Patané, Luan Clemente, Vincent Viala, Gabriela Ribeiro, Marta Giovanetti, Luiz de Alcantara, Olivia Teixeira, Maria Nonato, Loyze de Lima, Antonio Martins, Claudia dos Santos Barros, Elaine Marqueze, Jardelina de Souza Todão Bernardino, Debora Moretti, Ricardo Brassaloti, Raquel de Lello Rocha Campos Cassano, Pilar Mariani, Svetoslav Slavov, Rafael dos Santos, Evandra Rodrigues, Elaine Santos, Josiane Borges, Debora de La Roque, Joao Kitajima, Bibiana Santos, Patricia Assato, Felipe da Silva da Costa, Cecilia Banho, Livia Sacchetto, Marilia Moraes, Melissa Palmieri, Fabiana da Silva, Rejane Grotto, Jayme Souza-Neto, Mauricio Nogueira, Luiz Coutinho, Rodrigo Calado, Raul Neto, Dimas Covas, Simone Kashima, Maria Elias, Sandra Sampaio, Heidge Fukumasu
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Viruses
Viruses, Vol 13, Iss 2474, p 2474 (2021)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Universidade de São Paulo (USP)
instacron:USP
Viruses
Viruses, Vol 13, Iss 2474, p 2474 (2021)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2022-04-29T08:46:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5f33e5517272e11992827e30753af6
Autor:
Svetoslav Slavov, Richard D. Beger
Publikováno v:
Journal of Molecular Structure. 1249:131589
Similar to the opioid system, the endocannabinoid system which regulates immune response, memory and nociceptive thresholds, cell communication, appetite, and metabolism, also modulates (via Cannabinoid receptor type 1 - CB1R) the rewarding effects o
Autor:
Hong, Xing, Kristin W, Andrud, Ferenc, Soti, Anne, Rouchaud, Stephan C, Jahn, Ziang, Lu, Yeh-Hyon, Cho, Sophia, Habibi, Patrick, Corsino, Svetoslav, Slavov, James R, Rocca, Jon M, Lindstrom, Ron J, Lukas, William R, Kem
Publikováno v:
Mol Pharmacol
The two major nicotinic acetylcholine receptors (nAChRs) in the brain are the α4β2 and α7 subtypes. A “methyl scan” of the pyrrolidinium ring was used to detect differences in nicotine’s interactions with these two receptors. Each methylnico
Publikováno v:
Journal of Analytical and Applied Pyrolysis. 124:393-402
Algorithms applied to mass spectra of Salmonella isolates were used to achieve accurate and rapid serotyping. Two classification strategies were developed, one using all ions and the other, only 19. Without feature selection, classification based on