Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Svetlana Yu. Maklakova"'
Autor:
Svetlana Yu. Maklakova, Anton V. Lopukhov, Alexandr D. Khudyakov, Sergey V. Kovalev, Maria P. Mazhuga, Olga E. Chepikova, Andrey A. Zamyatnin, Alexander G. Majouga, Natalia L. Klyachko, Elena K. Beloglazkina
Publikováno v:
RSC Medicinal Chemistry. 14:56-64
Atorvastatin conjugates targeting the galactose-specific hepatic asialoglycoprotein receptor with improved stability are reported.
Autor:
Olga Y. Burenina, Dmitrii A Grishin, Yan A. Ivanenkov, Sergey V. Kovalev, Yury V. Timchenko, Alexander Vaneev, Svetlana Yu. Maklakova, Alexander G. Majouga, Natalia L. Klyachko, Rostislav A Petrov, Alexander Erofeev, Elena K. Beloglazkina, Emil Yu. Yamansarov, Roman Timoshenko, Petr V. Gorelkin, Elena V Lopatukhina, Evgenia E Ondar, Sergei A Evteev, Anton V Lopukhov, Sofiia R Mefedova
Publikováno v:
Molecular pharmaceutics. 18(1)
In this work, we have developed covalent and low molecular weight docetaxel delivery systems based on conjugation with N-acetyl-d-galactosamine and studied their properties related to hepatocellular carcinoma cells. The resulting glycoconjugates have
Autor:
G. I. Filkov, Rostislav A Petrov, Alexander G. Majouga, Yan A. Ivanenkov, Ekaterina V. Deyneka, Timofei S. Zatsepin, Stanislav A. Petrov, Victor E. Kotelianski, Sergey V. Kovalev, Elena K. Beloglazkina, Svetlana Yu. Maklakova, Irina V. Saltykova, Emil Yu. Yamansarov
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:503-508
Asialoglycoprotein receptor (ASGP-R) belongs to a wide family of C-type lectins and it is currently regarded as an attractive protein in the field of targeted drug delivery (TDD). It is abundantly expressed in hepatocytes and can be found predominant
Autor:
Rostislav A Petrov, Marina A Maximova, Yan A. Ivanenkov, Andrey A Ayginin, Zulfiya R Zileeva, Ilya A. Osterman, Dmitry S. Bezrukov, Alexey E. Machulkin, Katerina S Komarova, Victor A Terentiev, Mark S. Veselov, Vladimir A. Aladinskiy, Olga A. Dontsova, Anastasia V. Aladinskaya, Dmitry A. Skvortsov, Yulia V. Vakhitova, Renat S. Yamidanov, Alina A. Sofronova, Petr V. Sergiev, A. V. Chemeris, G. I. Filkov, Svetlana Yu. Maklakova, L. F. Zainullina, Victor G Kartsev, Alexey Kh Baimiev
Publikováno v:
Molecular diversity. 24(1)
A series of 5-oxo-4H-pyrrolo[3,2-b]pyridine derivatives was identified as novel class of highly potent antibacterial agents during an extensive large-scale high-throughput screening (HTS) program utilizing a unique double-reporter system—pDualrep2.
Autor:
Maria P Mazhuga, Alexander G. Majouga, Andrey D Chuprov, V.A. Naumenko, Nikolai V. Zyk, Elena K. Beloglazkina, Svetlana Yu. Maklakova
Publikováno v:
Carbohydrate Research. 489:107928
Autor:
Rostislav A Petrov, Olga V. Sergeeva, Elena K. Beloglazkina, Igor I. Kireev, Irina V. Saltykova, Emil Yu. Yamansarov, Timofei S. Zatsepin, Sergey V. Kovalev, Irina B. Alieva, Alexander G. Majouga, Alina A. Sofronova, Anastasiia V. Aladinskaia, Alexandre V. Trofimenko, Svetlana Yu. Maklakova, Ekaterina V. Deyneka, Renat S. Yamidanov, Yan A. Ivanenkov, Stanislav A. Petrov, Victor E. Kotelianski
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(3)
Asialoglycoprotein receptor (ASGP-R) is a promising biological target for drug delivery into hepatoma cells. Nevertheless, there are only few examples of small-molecule conjugates of ASGP-R selective ligand equipped by a therapeutic agent for the tre