Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Svetlana V. Vorona"'
Publikováno v:
ACS Omega, Vol 9, Iss 30, Pp 33000-33010 (2024)
Externí odkaz:
https://doaj.org/article/c8d26fd35d4e4249b09523e9bea272b6
Publikováno v:
ACS omega. 7(47)
P-glycoprotein (P-gp) is found to be of considerable interest for the design of drugs capable of treating chemoresistant tumors. This transporter is an interesting target for which an efficient approach has not yet been developed in terms of computer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0feb4a562c4536950a95f8a236d30cf9
https://pubmed.ncbi.nlm.nih.gov/36467933
https://pubmed.ncbi.nlm.nih.gov/36467933
Publikováno v:
Chemistry of Heterocyclic Compounds. 57:224-233
The review summarizes the advances in medicinal chemistry of tetrazole biologically active compounds and drugs over the past 15 years. Most of the considered compounds are at present actively studied, are in various stages of clinical trials, or have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::771037cde4229dd45243cc47b3dd3b85
https://doi.org/10.1007/s10593-021-02897-4
https://doi.org/10.1007/s10593-021-02897-4
Autor:
Tatyana A. Grigoreva, Aleksandra V. Sagaidak, Svetlana V. Vorona, Daria S. Novikova, Vyacheslav G. Tribulovich
Publikováno v:
ACS medicinal chemistry letters. 13(12)
Since the problem of transporter-mediated multidrug resistance of tumor cells is becoming increasingly important in cancer therapy, it is necessary to modulate the activity of efflux transporters of the ABC family, among which P-glycoprotein is the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7183073facf0646d87078302c961092c
https://pubmed.ncbi.nlm.nih.gov/36518704
https://pubmed.ncbi.nlm.nih.gov/36518704
Publikováno v:
ChemistrySelect. 4:10846-10850
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a67ea5f2f9583aaf4ea44321c2fad98
https://doi.org/10.1002/slct.201903162
https://doi.org/10.1002/slct.201903162
Autor:
Angelina Romanova, Vyacheslav G. Tribulovich, Svetlana V. Vorona, Aleksandra Sagaidak, Daria S. Novikova, Tatyana A. Grigoreva
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(18)
Chemoresistance is thought to be the cause of low treatment efficacy and mortality in more than 90% of patients with advanced cancer. The activation of drug efflux by P-glycoprotein is the key mechanism of resistance. All known P-gp inhibitors are us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c36c9349eec4d7ff6274074628a068
https://pubmed.ncbi.nlm.nih.gov/32738747
https://pubmed.ncbi.nlm.nih.gov/32738747
Autor:
Maxim Gureev, Vyacheslav G. Tribulovich, Svetlana V. Vorona, Daria S. Novikova, Tatyana A. Grigoreva, A. V. Garabadzhiu
Publikováno v:
Journal of computer-aided molecular design. 34(1)
Targeting of MDM2-p53 protein–protein interaction is a current approach for the development of potent anticancer agents. The classical pharmacophore hypothesis for the design of such molecules describes the three point binding of a small molecule i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b171a936cb330dabc1c2a252bdbb98db
https://pubmed.ncbi.nlm.nih.gov/31781989
https://pubmed.ncbi.nlm.nih.gov/31781989