Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Svetlana V Ukraintseva"'
Autor:
Alexander M Kulminski, Liang He, Irina Culminskaya, Yury Loika, Yelena Kernogitski, Konstantin G Arbeev, Elena Loiko, Liubov Arbeeva, Olivia Bagley, Matt Duan, Arseniy Yashkin, Fang Fang, Mikhail Kovtun, Svetlana V Ukraintseva, Deqing Wu, Anatoliy I Yashin
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006314 (2016)
Gaining insights into genetic predisposition to age-related diseases and lifespan is a challenging task complicated by the elusive role of evolution in these phenotypes. To gain more insights, we combined methods of genome-wide and candidate-gene stu
Externí odkaz:
https://doaj.org/article/4119000c967b4da88792985d10b82e1a
Autor:
Alexander M Kulminski, Irina Culminskaya, Konstantin G Arbeev, Liubov Arbeeva, Svetlana V Ukraintseva, Eric Stallard, Deqing Wu, Anatoliy I Yashin
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136319 (2015)
Insights into genetic origin of diseases and related traits could substantially impact strategies for improving human health. The results of genome-wide association studies (GWAS) are often positioned as discoveries of unconditional risk alleles of c
Externí odkaz:
https://doaj.org/article/784f72dffd714b2497ce9fd77a9121c3
Autor:
Alexander M Kulminski, Konstantin G Arbeev, Irina Culminskaya, Liubov Arbeeva, Svetlana V Ukraintseva, Eric Stallard, Kaare Christensen, Nicole Schupf, Michael A Province, Anatoli I Yashin
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004141 (2014)
Enduring interest in the Apolipoprotein E (ApoE) polymorphism is ensured by its evolutionary-driven uniqueness in humans and its prominent role in geriatrics and gerontology. We use large samples of longitudinally followed populations from the Framin
Externí odkaz:
https://doaj.org/article/5d494ba236074122986ea756b20368b0
Autor:
Vladimir A. Popov, Svetlana V. Ukraintseva, Hongzhe Duan, Anatoliy I. Yashin, Konstantin G. Arbeev
Publikováno v:
Frontiers in Dementia, Vol 3 (2024)
A growing research body supports the connection between neurodegenerative disorders, including Alzheimer's disease (AD), and traffic-related air pollution (TRAP). However, the underlying mechanisms are not well understood. A deeper investigation of T
Externí odkaz:
https://doaj.org/article/59a59703a25d41c1805514349ad0b76c
Autor:
Liang He, Yelena Kernogitski, Irina Kulminskaya, Yury Loika, Konstantin G. Arbeev, Elena Loiko, Olivia Bagley, Matt Duan, Arseniy Yashkin, Svetlana V. Ukraintseva, Mikhail Kovtun, Anatoliy I. Yashin, Alexander M. Kulminski
Publikováno v:
Frontiers in Genetics, Vol 8 (2018)
Externí odkaz:
https://doaj.org/article/8ffe8792af664030a54c65b7a2d41c50
Autor:
Konstantin G. Arbeev, Olivia Bagley, Arseniy P. Yashkin, Hongzhe Duan, Igor Akushevich, Svetlana V. Ukraintseva, Anatoliy I. Yashin
Publikováno v:
Mechanisms of Ageing and Development. 211:111791
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6a2ea1f7af16b28571bda1201d5c23d
https://doi.org/10.1016/j.mad.2023.111791
https://doi.org/10.1016/j.mad.2023.111791
Autor:
Liang He, Yelena Kernogitski, Irina Kulminskaya, Yury Loika, Konstantin G. Arbeev, Elena Loiko, Olivia Bagley, Matt Duan, Arseniy Yashkin, Svetlana V. Ukraintseva, Mikhail Kovtun, Anatoliy I. Yashin, Alexander M. Kulminski
Publikováno v:
Frontiers in Genetics, Vol 7 (2016)
Age-related diseases may result from shared biological mechanisms in intrinsic processes of aging. Genetic effects on age-related diseases are often modulated by environmental factors due to their little contribution to fitness or are mediated throug
Externí odkaz:
https://doaj.org/article/4592b2d26cfd4542aad0a22f5bb1ddb6
Autor:
Joseph M. Zmuda, Candace M. Kammerer, Allison L. Kuipers, Rehab A Sherlala, Svetlana V. Ukraintseva, Mary K. Wojczynski, Mary F. Feitosa, Jonas Mengel-From, Ryan L. Minster
Publikováno v:
J Gerontol A Biol Sci Med Sci
Sherlala, R A, Kammerer, C M, Kuiper, A L, Wojczynski, M K, Ukraintseva, S V, Feitosa, M F, Mengel-From, J, Zmuda, J M & Minster, R L 2021, ' Relationship between Serum IGF-1 and BMI differs by Age ', The journals of gerontology. Series A, Biological sciences and medical sciences, vol. 76, no. 7, pp. 1303–1308 . https://doi.org/10.1093/gerona/glaa282
Sherlala, R A, Kammerer, C M, Kuiper, A L, Wojczynski, M K, Ukraintseva, S V, Feitosa, M F, Mengel-From, J, Zmuda, J M & Minster, R L 2021, ' Relationship between Serum IGF-1 and BMI differs by Age ', The journals of gerontology. Series A, Biological sciences and medical sciences, vol. 76, no. 7, pp. 1303–1308 . https://doi.org/10.1093/gerona/glaa282
Background Serum levels of insulin-like growth factor 1 (IGF-1) and body mass index (BMI) are both associated with susceptibility to age-related diseases. Reports on the correlation between them have been conflicting, with both positive to negative c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d900355a499b993f29398b2af79cc826
https://doi.org/10.1093/gerona/glaa282
https://doi.org/10.1093/gerona/glaa282
Genetics of physiological dysregulation: findings from the long life family study using joint models
Autor:
Eric Stallard, Kaare Christensen, Joseph M. Zmuda, Anatoliy I. Yashin, Svetlana V. Ukraintseva, Hongzhe Duan, Bharat Thyagarajan, Olivia Bagley, Deqing Wu, Konstantin G. Arbeev, Alexander M. Kulminski, Joseph H. Lee
Publikováno v:
Aging (Albany NY)
Arbeev, K G, Bagley, O, Ukraintseva, S V, Wu, D, Duan, H, Kulminski, A M, Stallard, E, Christensen, K, Lee, J H, Thyagarajan, B, Zmuda, J M & Yashin, A I 2020, ' Genetics of physiological dysregulation : Findings from the long life family study using joint models ', Aging, vol. 12, no. 7, pp. 5920-5947 . https://doi.org/10.18632/aging.102987
Arbeev, K G, Bagley, O, Ukraintseva, S V, Wu, D, Duan, H, Kulminski, A M, Stallard, E, Christensen, K, Lee, J H, Thyagarajan, B, Zmuda, J M & Yashin, A I 2020, ' Genetics of physiological dysregulation : Findings from the long life family study using joint models ', Aging, vol. 12, no. 7, pp. 5920-5947 . https://doi.org/10.18632/aging.102987
Recently, Mahalanobis distance (DM) was suggested as a statistical measure of physiological dysregulation in aging individuals. We constructed DM variants using sets of biomarkers collected at the two visits of the Long Life Family Study (LLFS) and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b9d2cbff0a5885d7c83676e9697a55
https://doi.org/10.18632/aging.102987
https://doi.org/10.18632/aging.102987
Autor:
Svetlana V. Ukraintseva, Konstantin G. Arbeev, Alexander M. Kulminski, Matt Duan, Igor Akushevich, Olivia Bagley, Galina Gorbunova, Deqing Wu, Arseniy P. Yashkin, Anatoliy I. Yashin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
A major goal of aging research is identifying genetic targets that could be used to slow or reverse aging – changes in the body and extend limits of human lifespan. However, majority of genes that showed the anti-aging and pro-survival effects in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8f9a7448e2c7d8c99f1fe537cb75b8
https://www.frontiersin.org/articles/10.3389/fcell.2021.692020/full
https://www.frontiersin.org/articles/10.3389/fcell.2021.692020/full