Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Svetlana Soboleva"'
Autor:
Svetlana Soboleva, Ryo Kurita, Fredrik Ek, Hugo Åkerstrand, Rita Silvério-Alves, Roger Olsson, Yukio Nakamura, Kenichi Miharada
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
In an imaging-based screen of >3,300 compounds compounds, Soboleva et al identify HDAC inhibitors as mediators of erythroid cell enucleation. They further show that the erythroid-specific cell membrane protein, SPTA1, is downregulated in HDAC inhibit
Externí odkaz:
https://doaj.org/article/61f572de14eb48a18df29210fe97c443
Publikováno v:
International Journal of Hematology. 115:481-488
Hematopoietic stem cells (HSC) give rise to all types of blood lineages, including red blood cells (RBC). Hematopoietic stem/progenitor cells (HSPC) are known to be functionally diverse in terms of their self-renewal potential and lineage output. Con
Publikováno v:
Human Cell. 35:408-417
Ex vivo manufactured red blood cells (RBC) generated from immortalized erythroid cell lines which can continuously grow are expected to become a significant alternative in future transfusion therapies. The ectopic expression of human papilloma virus
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6677
Only some human organs, including the liver, are capable of very weak self-regeneration. Some marine echinoderms are very useful for studying the self-regeneration processes of organs and tissues. For example, sea cucumbers Eupentacta fraudatrix (hol
Autor:
Svetlana Soboleva, Kenichi Miharada
Publikováno v:
International journal of hematology. 116(2)
Enucleation is a crucial event during the erythropoiesis, implicating drastic morphologic and transcriptomic/proteomic changes. While many genes deletion lead to failed or impaired enucleation have been identified, directly triggering the erythroid m
Autor:
Ermin Schadich, Susanne Nylén, Soňa Gurská, Jana Kotulová, Sergey Andronati, Victor Pavlovsky, Svetlana Soboleva, Pavel Polishchuk, Marián Hajdúch, Petr Džubák
Publikováno v:
Parasitology international. 91
A series of 1-aryl-4-(phthalimidoalkyl) piperazines and 1-aryl-4-(naphthalimidoalkyl) piperazines were retrieved from a proprietary library based on their high structural similarity to haloperidol, an antipsychotic with antiparasitic activity, and as
Autor:
Hugo Åkerstrand, Rita Silvério-Alves, Ryo Kurita, Kenichi Miharada, Svetlana Soboleva, Yukio Nakamura, Fredrik Ek, Roger Olsson
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Immortalized erythroid cell lines are expected to be a promising source of ex vivo manufactured red blood cells (RBCs), however the induction of enucleation in these cell lines is inefficient at present. We utilized an imaging-based high-throughput s
Publikováno v:
Advances in Social Science, Education and Humanities Research.
Publikováno v:
Proceedings of the National Academy of Sciences
Autor:
Valgardur, Sigurdsson, Youichi, Haga, Hajime, Takei, Els, Mansell, Chizuko, Okamatsu-Haga, Mitsuyoshi, Suzuki, Visnja, Radulovic, Mark, van der Garde, Shuhei, Koide, Svetlana, Soboleva, Mats, Gåfvels, Hiroshi, Nittono, Akira, Ohara, Kenichi, Miharada
Publikováno v:
Blood Adv
Chemotherapeutic agents can reduce bone marrow (BM) activity, causing myelosuppression, a common life-threatening complication of cancer treatment. It is challenging to predict the patients in whom prolonged myelosuppression will occur, resulting in