Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Svetlana Senina"'
Autor:
Moushimi Amaya, Kelsey Voss, Gavin Sampey, Svetlana Senina, Cynthia de la Fuente, Claudius Mueller, Valerie Calvert, Kylene Kehn-Hall, Calvin Carpenter, Fatah Kashanchi, Charles Bailey, Soren Mogelsvang, Emanuel Petricoin, Aarthi Narayanan
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86745 (2014)
Venezuelan equine encephalitis virus (VEEV) belongs to the genus Alphavirus, family Togaviridae. VEEV infection is characterized by extensive inflammation and studies from other laboratories implicated an involvement of the NF-κB cascade in the in v
Externí odkaz:
https://doaj.org/article/cd6a2ad0145f41758f9ef5a709426b2c
Autor:
Kylene Kehn-Hall, Aarthi Narayanan, Lindsay Lundberg, Gavin Sampey, Chelsea Pinkham, Irene Guendel, Rachel Van Duyne, Svetlana Senina, Kimberly L Schultz, Eric Stavale, M Javad Aman, Charles Bailey, Fatah Kashanchi
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34761 (2012)
Alphaviruses, including Venezuelan Equine Encephalitis Virus (VEEV), cause disease in both equine and humans that exhibit overt encephalitis in a significant percentage of cases. Features of the host immune response and tissue-specific responses may
Externí odkaz:
https://doaj.org/article/a88941b1091b4188b28cdceedc7b7130
Autor:
Brian D. Carey, Claudius Mueller, Faye Sharman, Todd M. Bell, Alan Baer, Kylene Kehn-Hall, Caitlin Woodson, Lindsay Lundberg, Cynthia de la Fuente, Virginia Espina, Shih-Chao Lin, Chelsea Pinkham, Elizabeth A. Chlipala, Ashwini Brahms, Svetlana Senina, Lance A. Liotta
Publikováno v:
Antiviral research. 143
Despite over 60 years of research on antiviral drugs, very few are FDA approved to treat acute viral infections. Rift Valley fever virus (RVFV), an arthropod borne virus that causes hemorrhagic fever in severe cases, currently lacks effective treatme
Autor:
Dmitri Sviridov, Svetlana Senina, Tatiana Pushkarsky, Fatah Kashanchi, Irene Guendel, Michael Bukrinsky, Rachel Van Duyne, Larisa Dubrovsky
Publikováno v:
Biochemical and Biophysical Research Communications. 419:95-98
HIV-infected subjects are at high risk of developing atherosclerosis, in part due to virus-induced impairment of HDL metabolism. Here, using as a model of HIV infection the NOD.Cg-Prkdc(scid)IL2rg(tm1Wjl)/SzJ (NSG) mice humanized by human stem cell t
Autor:
John K. Rose, Guillaume Delmas, Steven Park, David S. Perlin, Svetlana Senina, Anasuya Chattopadhyay, Rema Suresh
Publikováno v:
Vaccine
We have developed an experimental recombinant vesicular stomatitis virus (VSV) vectored plague vaccine expressing a secreted form of Yersinia pestis low calcium response protein V (LcrV) from the first position of the VSV genome. This vector, given i
Autor:
Neha Bansal, Aarthi Narayanan, Ashwini Benedict, Kylene Kehn-Hall, Cynthia de la Fuente, Idris Hooper, Bradford W. Gutting, Lindsay Lundberg, Svetlana Senina
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Frontiers in Microbiology
Frontiers in Microbiology
There are currently no FDA-approved therapeutics available to treat Rift Valley fever virus (RVFV) infection. In an effort to repurpose drugs for RVFV treatment, a library of FDA-approved drugs was screened to determine their ability to inhibit RVFV.
Autor:
Idris Hooper, Cathaleen Madsen, Alexandra Johnson, Cynthia de la Fuente, Brenda L. Fredricksen, Lisa I. Hoover, Kylene Kehn-Hall, Lindsay Lundberg, Svetlana Senina, Jonathan L. Jacobs, Nazly Shafagati, Jonathan D. Dinman
Publikováno v:
Antiviral research. 112
Venezuelan equine encephalitis virus (VEEV) is classified as a Category B Select Agent and potential bioterror weapon for its severe disease course in humans and equines and its potential for aerosol transmission. There are no current FDA licensed va
Autor:
Leonard D. Shultz, Svetlana Senina, Rachel Van Duyne, Kylene Kehn-Hall, Benjamin Lepene, Ravi K. Das, Elizabeth Jaworski, Chen Zeng, Hao Chen, Aarthi Narayanan, Sergey Iordanskiy, Gavin C. Sampey, Fatah Kashanchi, Irene Guendel, Mohammed Saifuddin
Publikováno v:
Journal of virology. 88(2)
The implementation of new antiretroviral therapies targeting transcription of early viral proteins in postintegrated HIV-1 can aid in overcoming current therapy limitations. Using high-throughput screening assays, we have previously described a novel
Autor:
Charles L. Bailey, Lindsay Lundberg, Fatah Kashanchi, Rachel Van Duyne, Irene Guendel, Alan Baer, Aarthi Narayanan, Amy L. Hartman, Ravi K. Das, Michael J. Turell, Bhaskar C. Das, Kylene Kehn-Hall, Svetlana Senina, Laura M. Bethel
Publikováno v:
The Journal of biological chemistry. 287(40)
Rift Valley fever virus (RVFV) is an arbovirus that is classified as a select agent, an emerging infectious virus, and an agricultural pathogen. Understanding RVFV-host interactions is imperative to the design of novel therapeutics. Here, we report t
Autor:
Eric Stavale, Fatah Kashanchi, Irene Guendel, Aarthi Narayanan, Kylene Kehn-Hall, Lindsay Lundberg, Chelsea Pinkham, Kimberly L. W. Schultz, Charles L. Bailey, Gavin C. Sampey, Rachel Van Duyne, M. Javad Aman, Svetlana Senina
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 4, p e34761 (2012)
PLoS ONE, Vol 7, Iss 4, p e34761 (2012)
Alphaviruses, including Venezuelan Equine Encephalitis Virus (VEEV), cause disease in both equine and humans that exhibit overt encephalitis in a significant percentage of cases. Features of the host immune response and tissue-specific responses may