Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Svetlana Minakhina"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Unlike other thyroid hormone receptors (THRs), the beta 2 isoform (THRB2) has a restricted expression pattern and is uniquely and abundantly phosphorylated at a conserved serine residue S101 (S102 in humans). Using tagged and or phosphorylat
Externí odkaz:
https://doaj.org/article/0682ca5697314e6cad4cca2c9faf255c
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190367 (2018)
The TET (Ten-eleven translocation) 1, 2 and 3 proteins have been shown to function as DNA hydroxymethylases in vertebrates and their requirements have been documented extensively. Recently, the Tet proteins have been shown to also hydroxylate 5-methy
Externí odkaz:
https://doaj.org/article/b74f35f6f5674d5e9f44459e63a19760
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147631 (2016)
Zfrp8/PDCD2 is a highly conserved protein essential for stem cell maintenance in both flies and mammals. It is also required in fast proliferating cells such as cancer cells. Our previous studies suggested that Zfrp8 functions in the formation of mRN
Externí odkaz:
https://doaj.org/article/3ab099281e7e4f159a190967d3f7781c
Autor:
Rucha Janodia, Michael Brotherton, Sanya Bansal, Srikanth Tadepalli, Svetlana Minakhina, Vanessa De Oliveira, Alice Zhang, Fredric E. Wondisford
Publikováno v:
Thyroid
Background: Thyroid hormone (TH) action is mediated by three major thyroid hormone receptor (THR) isoforms α1, β1, and β2 (THRA1, THRB1, and THRB2). These THRs and a fourth major but non-TH binding isoform, THRA2, are encoded by two genes Thra and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108d3de92c63d84862d687daf54accc4
https://doi.org/10.1089/thy.2019.0763
https://doi.org/10.1089/thy.2019.0763
Publikováno v:
Proc Natl Acad Sci U S A
Fasting induces profound changes in the hypothalamic–pituitary–thyroid (HPT) axis. After binding thyroid hormone (TH), the TH receptor beta 2 isoform (THRB2) represses Trh and Tsh subunit genes and is the principle negative regulator of the HPT a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3802753f824bba7544ab764f644317ef
https://pubmed.ncbi.nlm.nih.gov/34544870
https://pubmed.ncbi.nlm.nih.gov/34544870
Autor:
Collin Wetzel, Patrick A. Limbach, Véronique Kruys, Bouchra Hassabi, Stephan Awe, Long Vo Ngoc, Alexander Brehm, Benjamin Delatte, François Fuks, Judith Kreher, Emilie Calonne, Cyril Gueydan, Catherine Creppe, Elise Bonvin, Romuald Soin, Matthieu Defrance, Evelyne Collignon, Pascale Putmans, Ruth Steward, Rachel Deplus, Svetlana Minakhina, Fei Wang
Publikováno v:
Science. 351:282-285
Chemical modification of RNA for function Chemical modifications play an important role in modifying and regulating the function of DNA and RNA. Delatte et al. show that, in the fruit fly, many messenger RNAs (mRNAs) contain the modified base 5-hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4be14051e1e0990db157359a17922ab
https://doi.org/10.1126/science.aac5253
https://doi.org/10.1126/science.aac5253
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190367 (2018)
PLoS ONE
PLoS ONE
The TET (Ten-eleven translocation) 1, 2 and 3 proteins have been shown to function as DNA hydroxymethylases in vertebrates and their requirements have been documented extensively. Recently, the Tet proteins have been shown to also hydroxylate 5-methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a410e7bad1ca93755b63f1943e42c9
http://europepmc.org/articles/PMC5764297?pdf=render
http://europepmc.org/articles/PMC5764297?pdf=render
Autor:
Aniket Sidhaye, Amy Suhotliv, Shuiqing Qiu, Svetlana Minakhina, Fredric E. Wondisford, Michael Brotherton, Vitor M S Pinto
Publikováno v:
Endocrinology. 158(9)
Thyroid hormone (TH) action is mediated by the products of two genes, TH receptor (THR)α (THRA) and THRβ (THRB) that encode several closely related receptor isoforms with differing tissue distributions. The vast majority of THR isoform-specific eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d4135c4ab53b751dbba7841a3c0cf8
https://pubmed.ncbi.nlm.nih.gov/28911178
https://pubmed.ncbi.nlm.nih.gov/28911178
Autor:
Benjamin, Delatte, Fei, Wang, Long Vo, Ngoc, Evelyne, Collignon, Elise, Bonvin, Rachel, Deplus, Emilie, Calonne, Bouchra, Hassabi, Pascale, Putmans, Stephan, Awe, Collin, Wetzel, Judith, Kreher, Romuald, Soin, Catherine, Creppe, Patrick A, Limbach, Cyril, Gueydan, Véronique, Kruys, Alexander, Brehm, Svetlana, Minakhina, Matthieu, Defrance, Ruth, Steward, François, Fuks
Publikováno v:
Science (New York, N.Y.). 351(6270)
Hydroxymethylcytosine, well described in DNA, occurs also in RNA. Here, we show that hydroxymethylcytosine preferentially marks polyadenylated RNAs and is deposited by Tet in Drosophila. We map the transcriptome-wide hydroxymethylation landscape, rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a094c162790c472156cdcdc00f43ff6f
https://pubmed.ncbi.nlm.nih.gov/26816380
https://pubmed.ncbi.nlm.nih.gov/26816380
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147631 (2016)
PLoS ONE
PLoS ONE
Zfrp8/PDCD2 is a highly conserved protein essential for stem cell maintenance in both flies and mammals. It is also required in fast proliferating cells such as cancer cells. Our previous studies suggested that Zfrp8 functions in the formation of mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6961715a95e753807f99e7131d2322ab
http://europepmc.org/articles/PMC4726551?pdf=render
http://europepmc.org/articles/PMC4726551?pdf=render