Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Svetlana I. Nihtyanova"'
Autor:
Abeer Ghuman, Dinesh Khanna, Celia J F Lin, Daniel E Furst, Ganesh Raghu, Fernando J Martinez, Mauro Zucchetto, Suiyuan Huang, Angus Jennings, Svetlana I Nihtyanova, Christopher P Denton
Publikováno v:
Rheumatology.
Objectives Explore prognostic and predictive markers of systemic sclerosis-associated interstitial lung disease (SSc-ILD) outcomes in a phase 3 trial (focuSSced) and prognostic markers in a real-world cohort (SMART). Methods The focuSSced SSc-ILD sub
Autor:
Svetlana I. Nihtyanova, Benjamin E. Schreiber, Voon H. Ong, Athol U. Wells, John G. Coghlan, Christopher P. Denton
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.).
Pulmonary hypertension (PH) is a serious complication of systemic sclerosis (SSc). We explore prediction of short-term risk for PH using serial pulmonary function tests (PFTs) and other disease features.Subjects with SSc, disease onset≥10 years pri
Autor:
Charles Murray, Rory H Maclean, Fiza Ahmed, Voon H Ong, Christopher P. Denton, Svetlana I. Nihtyanova
Publikováno v:
Rheumatology. 61:781-786
Objectives To assess the prevalence and burden of SSc-related gastrointestinal dysfunction (SSc-GI) and to evaluate associations with demographic, clinical and serological characteristics. Methods Patients completed the UCLA SCTC GIT 2.0 questionnair
Publikováno v:
J Scleroderma Relat Disord
Background: Linear morphoea is a severe morphoea subtype associated with extracutaneous manifestations, potentially permanent disfigurement and functional impairment. Linear morphoea is more prevalent in paediatric patients, and knowledge of disease
Autor:
Emma Derrett-Smith, Christopher P. Denton, Jennifer Harvey, Alper Sari, Voon H Ong, Svetlana I. Nihtyanova, Anna Leslie, Carmen Fonseca
Publikováno v:
Arthritis & Rheumatology. 72:465-476
OBJECTIVE To describe the associations between autoantibodies, clinical presentation, and outcomes among patients with systemic sclerosis (SSc) in order to develop a novel SSc classification scheme that would incorporate both antibodies and the cutan
Autor:
Felix Chua, Christopher P. Denton, Dina Visca, Peter M. George, Cécile Daccord, Elisabetta A. Renzoni, Philip L. Molyneaux, Maria Kokosi, Louise V. Wain, Angelo De Lauretis, Toby M. Maher, David Abraham, Vasilis Kouranos, Athol U. Wells, George Margaritopoulos, Carmel Stock, Svetlana I. Nihtyanova, Voon H Ong
Publikováno v:
Clinical Rheumatology. 39:1173-1179
Although several genetic associations with scleroderma (SSc) are defined, very little is known on genetic susceptibility to SSc-associated interstitial lung disease (SSc-ILD). A number of common polymorphisms have been associated with SSc-ILD, but mo
Autor:
Silvia Bellando-Randone, Ulrich A. Walker, Marc Frerix, Svetlana I. Nihtyanova, Veronika Lóránd, Marco Matucci-Cerinic, Ingo H. Tarner, Serena Vettori, Veronika K. Jaeger, Ulf Müller-Ladner, Giuseppina Abignano, Jérôme Avouac, G. Riemekasten, Cosimo Bruni, Oliver Distler, L. Czirják, Yannick Allanore, Alberto Moggi-Pignone, F. Del Galdo, Jelena Blagojevic, Laura Cometi, Dörte Huscher, Christopher P. Denton, Britta Maurer, Serena Guiducci, Elise Siegert
Publikováno v:
Clinical Rheumatology. 39:27-36
DeSScipher is the first European multicentre study on management of systemic sclerosis (SSc), and its observational trial 1 (OT1) evaluated the efficacy of different drugs for digital ulcer (DU) prevention and healing. The aim of this study was to as
Autor:
Julia Spierings, Svetlana I. Nihtyanova, Christopher P. Denton, Kristina E N Clark, Jacob M. van Laar, Voon H Ong, Emma Derrett-Smith
Publikováno v:
Rheumatology (Oxford, England). 61(5)
Objectives The aim of this study was to explore outcomes in a cohort of dcSSc patients fulfilling eligibility criteria for stem cell transplantation (SCT) studies but receiving standard immunosuppression. Methods From a large single-centre dcSSc coho
Publikováno v:
Rheumatology. 59
Background The FaSScinate and FocuSSced trials of tocilizumab versus placebo in early diffuse systemic sclerosis (SSc) highlighted the potential impact of tocilizumab on lung function with preservation of lung function in those treated with tocilizum
Autor:
Svetlana I. Nihtyanova, Voon H Ong, Carmen Fonseca, Emma Derrett-Smith, Christopher P. Denton
Publikováno v:
Rheumatology. 59
Background Skin thickness improves over time in most diffuse cutaneous systemic sclerosis (dcSSc) patients and the use of group level skin score (mRss) as an endpoint is clinical trials can be challenging. We explore the association between individua