The Genome-Wide Analysis of Carcinoembryonic Antigen Signaling by Colorectal Cancer Cells Using RNA Sequencing.

Autor: Olga Bajenova, Anna Gorbunova, Igor Evsyukov, Michael Rayko, Svetlana Gapon, Ekaterina Bozhokina, Alexander Shishkin, Stephen J O'Brien

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0161256 (2016)

Сarcinoembryonic antigen (CEA, CEACAM5, CD66) is a promoter of metastasis in epithelial cancers that is widely used as a prognostic clinical marker of metastasis. The aim of this study is to identify the network of genes that are associated with CEA

Externí odkaz: https://doaj.org/article/72c27e12dc914564b92c5098365e925c

Reconstructing human Brown Fat developmental trajectory in vitro

Autor: Jyoti Rao, Jerome Chal, Fabio Marchianò, Chih-Hao Wang, Ziad Al Tanoury, Svetlana Gapon, Yannis Djeffal, Alicia Mayeuf-Louchart, Ian Glass, Elizabeth M. Sefton, Bianca Habermann, Gabrielle Kardon, Fiona M. Watt, Yu-Hua Tseng, Olivier Pourquié

Brown adipocytes represent a specialized type of mammalian adipocytes able to uncouple nutrient catabolism from ATP generation to dissipate energy as heat. They play an important role in mammals, allowing non-shivering thermogenesis to regulate body

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87c8dd3cac22eb58bb3a1af158dd4112
https://doi.org/10.1101/2022.06.01.494355

Metabolic regulation of species-specific developmental rates

Autor: Margarete Diaz-Cuadros, Teemu P. Miettinen, Owen S. Skinner, Dylan Sheedy, Carlos Manlio Díaz-García, Svetlana Gapon, Alexis Hubaud, Gary Yellen, Scott R. Manalis, William M. Oldham, Olivier Pourquié

Publikováno v: Nature

Animals display significant inter-species variation in the rate of embryonic development despite broad conservation of the overall sequence of developmental events. Differences in biochemical reaction speeds, including the rates of protein production

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3e33cad23f3154c0e5bc810deb5174
https://pubmed.ncbi.nlm.nih.gov/36599986

Prednisolone rescues Duchenne muscular dystrophy phenotypes in human pluripotent stem cell-derived skeletal muscle in vitro

Autor: Charlotte Fugier-Schmucker, Fanny Bousson, Aurore Hick-Colin, Fabio Marchiano, Daniel Sieiro, Ziad Al Tanoury, Jérome Chal, Harold M. McNamara, Erica Wagner, Rhonda Bassel-Duby, Kevin Kit Parker, Alejandra Rodríguez-delaRosa, Svetlana Gapon, Vandana Gupta, Olivier Pourquié, Jyoti Rao, Eric N. Olson, Thomas Cherrier, John F. Zimmerman, Alexander P. Nesmith, Bianca Habermann, Adam E. Cohen

Publikováno v: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (28), pp.e2022960118. ⟨10.1073/pnas.2022960118⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (28), pp.e2022960118. ⟨10.1073/pnas.2022960118⟩

International audience; Duchenne muscular dystrophy (DMD) is a devastating genetic disease leading to degeneration of skeletal muscles and premature death. How dystrophin absence leads to muscle wasting remains unclear. Here, we describe an optimized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0650604b0b4141c7d51281a92b3873b5
https://pubmed.ncbi.nlm.nih.gov/34260377

The Genome-Wide Analysis of Carcinoembryonic Antigen Signaling by Colorectal Cancer Cells Using RNA Sequencing

Autor: Stephen J. O'Brien, Anna Gorbunova, Michael Rayko, Igor Evsyukov, Olga Bajenova, Ekaterina Bozhokina, Svetlana Gapon, Alexander A. Shishkin

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0161256 (2016)
PLoS ONE

Сarcinoembryonic antigen (CEA, CEACAM5, CD66) is a promoter of metastasis in epithelial cancers that is widely used as a prognostic clinical marker of metastasis. The aim of this study is to identify the network of genes that are associated with CEA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d56ede877039b3b7f4d53eb800a9a4
https://resolver.caltech.edu/CaltechAUTHORS:20160913-090623240