Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Svetlana G. Zubova"'
Publikováno v:
Frontiers in Bioscience-Scholar, Vol 14, Iss 1, p 003 (2022)
The approach to the study of autophagy has been undergoing considerable change lately: from investigations of the protein components of autophagic machinery to its regulation at different molecular levels. Autophagy is being examinated not only as a
Externí odkaz:
https://doaj.org/article/a768cbcc9c914cf9b202c95470b9867d
Publikováno v:
Cell and Tissue Biology. 7:126-135
We have studied the role of the stress kinases p38 and JNK1,2 in premature senescence induced by sodium butyrate (NaBut), a histone deacetylase inhibitor, in mouse embryonic fibroblasts transformed by E1A+cHa-Ras oncogenes. It was found that transfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c60d279f7a4d856329b317ad1f19397c
https://doi.org/10.1134/s1990519x13020065
https://doi.org/10.1134/s1990519x13020065
Autor:
Valery A. Pospelov, Bykova Tv, Mikhail V. Blagosklonny, Svetlana G. Zubova, Olga V. Leontieva, Pospelova Tv
Publikováno v:
Cell Cycle. 11:2402-2407
The TOR (target of rapamycin) pathway is involved in aging in diverse organisms from yeast to mammals. We have previously demonstrated in human and rodent cells that mTOR converts stress-induced cell cycle arrest to irreversible senescence (geroconve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c84fd4ea53e92cb0febf8d3bf2ec53a9
https://doi.org/10.4161/cc.20882
https://doi.org/10.4161/cc.20882
Autor:
Zoya N. Demidenko, Valery A. Pospelov, Svetlana G. Zubova, Tatiana V. Pospelova, Mikhail V. Blagosklonny, Elena I. Bukreeva
Publikováno v:
Cell Cycle. 8:1888-1895
When the cell cycle is arrested but cellular growth is not, then cells senesce, permanently losing proliferative potential. Here we demonstrated that the duration of cell cycle arrest determines a progressive loss of proliferative capacity. In human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e97d05698104d9914331dc40a7cd911
https://doi.org/10.4161/cc.8.12.8606
https://doi.org/10.4161/cc.8.12.8606
Autor:
Tatyana V. Pospelova, Svetlana G. Zubova, Natalia M Yartzeva, Bykova Tv, Natalia V Katolikova, Valery A. Pospelov
Publikováno v:
Cell cycle (Georgetown, Tex.). 12(24)
Primary rodent cells undergo replicative senescence, independent from telomere shortening. We have recently shown that treatment with rapamycin during passages 3–7 suppressed replicative senescence in rat embryonic fibroblasts (REFs), which otherwi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a1f73ac913f2707262143f5d382e2c
https://pubmed.ncbi.nlm.nih.gov/24296616
https://pubmed.ncbi.nlm.nih.gov/24296616
Autor:
Tatiana V. Pospelova, Svetlana G. Zubova, Bykova Tv, Alexander A. Bardin, Vasily S. Romanov, Valery A. Pospelov
Publikováno v:
Biochimie. 93(9)
Cyclin-dependent kinase inhibitor p21(Waf1) is known to have alternative functions associated with positive regulation of proliferation, actin cytoskeleton remodeling and suppression of apoptosis. The goal of the present study was to assess the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29574ac8ca2853937de02653db1b835
https://pubmed.ncbi.nlm.nih.gov/21554922
https://pubmed.ncbi.nlm.nih.gov/21554922
Autor:
Valery A. Pospelov, Vasily S. Romanov, Svetlana G. Zubova, S. B. Svetlikova, Albert J. Fornace, Tatiana V. Pospelova, Bykova Tv, Abramova Mv, Nikolai D. Aksenov
Publikováno v:
Cell cycle (Georgetown, Tex.). 9(19)
Cell senescence is characterized by senescent morphology and permanent loss of proliferative potential. HDAC inhibitors (HDACI) induce senescence and/or apoptosis in many types of tumor cells. Here, we studied the role of cyclin-kinase inhibitor p21(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760347836a5baf8b2a38010daee8e007
https://pubmed.ncbi.nlm.nih.gov/20935470
https://pubmed.ncbi.nlm.nih.gov/20935470
Publikováno v:
Europe PubMed Central
A pentapaptide, pyroGlu-Glu-Asp-Ser-GlyOH (EPP), isolated from mouse epidermis, inhibits mitoses and enhances differentiation in primary cultures and in transformed mouse epidermal cells in vitro (Elgjo et al. 1986 b). The present work demonstrates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a65019ca2a5af7c73046bb6a6789a34
https://doi.org/10.1007/bf02899703
https://doi.org/10.1007/bf02899703