Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Svetlana Deryusheva"'
Autor:
Svetlana Deryusheva, Joseph G. Gall
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 457 (2019)
Site-specific 2’-O-ribose methylation is an abundant post-transcriptional modification mediated by small non-coding nuclear RNAs known as box C/D modification guide RNAs. The minimal structural requirements for these guide RNAs to function in highe
Externí odkaz:
https://doaj.org/article/d3f968f07ca342918f741eff6bbd304a
Publikováno v:
RNA
In eukaryotes, rRNAs and spliceosomal snRNAs are heavily modified posttranscriptionally. Pseudouridylation and 2’-O-methylation are the most abundant types of RNA modifications. They are mediated by modification guide RNAs, also known as small nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6115f58cc9e6e9c89d49eaaf861ed19
https://europepmc.org/articles/PMC8522698/
https://europepmc.org/articles/PMC8522698/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Small nucleolar (sno)RNAs generally guide ribosomal RNA and small nuclear RNA modifications, essential events for ribosome and spliceosome biogenesis and function. Most are processed in the nucleus from lariat intronic RNAs, which are un
Autor:
Varun Gupta, Denis L. J. Lafontaine, Ludivine Wacheul, Joseph G. Gall, Jonathan Bizarro, Svetlana Deryusheva, U. Thomas Meier, Felix G.M. Ernst
Publikováno v:
bioRxiv
Genes Dev
Genes Dev
Spliceosomal small nuclear RNAs (snRNAs) are modified by small Cajal body (CB) specific ribonucleoproteins (scaRNPs) to ensure snRNP biogenesis and pre-mRNA splicing. However, the function and subcellular site of snRNA modification are largely unknow
Autor:
Joseph G. Gall, Svetlana Deryusheva
Publikováno v:
RNA. 23:1060-1067
The pseudouridine at position 43 in vertebrate U2 snRNA is one of the most conserved post-transcriptional modifications of spliceosomal snRNAs; the equivalent position is pseudouridylated in U2 snRNAs in different phyla including fungi, insects, and
Autor:
Joseph G. Gall, Svetlana Deryusheva
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 457 (2019)
Biomolecules
Biomolecules
Site-specific 2’-O-ribose methylation is an abundant post-transcriptional modification mediated by small non-coding nuclear RNAs known as box C/D modification guide RNAs. The minimal structural requirements for these guide RNAs to function in highe
Autor:
Svetlana Deryusheva, Svetlana Galkina, Elena I. Koshel, Elena Gaginskaya, Alsu F. Saifitdinova, A. G. Dyomin
Publikováno v:
Cell and Tissue Research. 366:533-542
Despite long-term exploration into ribosomal RNA gene functioning during the oogenesis of various organisms, many intriguing problems remain unsolved. In this review, we describe nucleolus organizer region (NOR) activity in avian oocytes. Whereas ooc
Autor:
Svetlana Deryusheva, Joseph G. Gall
Publikováno v:
RNA (New York, N.Y.). 25(1)
Posttranscriptional modifications of rRNA occur in the nucleolus where rRNA modification guide RNAs, or snoRNAs, concentrate. On the other hand, scaRNAs, the modification guide RNAs for spliceosomal snRNAs, concentrate in the Cajal body (CB). It is g
Autor:
Svetlana Deryusheva, Joseph G. Gall
Publikováno v:
RNA. 19:1802-1814
The spliceosomal small nuclear RNAs (snRNAs) are modified post-transcriptionally by introduction of pseudouridines and 2′-O-methyl modifications, which are mediated by box H/ACA and box C/D guide RNAs, respectively. Because of their concentration i
Publikováno v:
RNA
RNA, Cold Spring Harbor Laboratory Press, 2012, 18 (1), pp.31--36. ⟨10.1261/rna.030106.111⟩
RNA, Cold Spring Harbor Laboratory Press, 2012, 18 (1), pp.31--36. ⟨10.1261/rna.030106.111⟩
International audience; The survival of motor neuron (SMN) protein plays an important role in the biogenesis of spliceosomal snRNPs and is one factor required for the integrity of nuclear Cajal bodies (CBs). CBs are enriched in small CB-specific (sca