Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Svetlana Bezprozvannaya"'
Autor:
Matthieu Dos Santos, Akansha M. Shah, Yichi Zhang, Svetlana Bezprozvannaya, Kenian Chen, Lin Xu, Weichun Lin, John R. McAnally, Rhonda Bassel-Duby, Ning Liu, Eric N. Olson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Skeletal muscle fibers express distinct gene programs during development and maturation, but the underlying gene regulatory networks that confer stage-specific myofiber properties remain unknown. To decipher these distinctive gene programs a
Externí odkaz:
https://doaj.org/article/be1965dd27c140d994a010d7e4345d38
Autor:
Catherine A. Makarewich, Kedryn K. Baskin, Amir Z. Munir, Svetlana Bezprozvannaya, Gaurav Sharma, Chalermchai Khemtong, Akansha M. Shah, John R. McAnally, Craig R. Malloy, Luke I. Szweda, Rhonda Bassel-Duby, Eric N. Olson
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3701-3709 (2018)
Summary: Micropeptide regulator of β-oxidation (MOXI) is a conserved muscle-enriched protein encoded by an RNA transcript misannotated as non-coding. MOXI localizes to the inner mitochondrial membrane where it associates with the mitochondrial trifu
Externí odkaz:
https://doaj.org/article/7104ce443c914948b23d40e5e3e40066
Autor:
Catherine A Makarewich, Amir Z Munir, Gabriele G Schiattarella, Svetlana Bezprozvannaya, Olga N Raguimova, Ellen E Cho, Alexander H Vidal, Seth L Robia, Rhonda Bassel-Duby, Eric N Olson
Publikováno v:
eLife, Vol 7 (2018)
Calcium (Ca2+) dysregulation is a hallmark of heart failure and is characterized by impaired Ca2+ sequestration into the sarcoplasmic reticulum (SR) by the SR-Ca2+-ATPase (SERCA). We recently discovered a micropeptide named DWORF (DWarf Open Reading
Externí odkaz:
https://doaj.org/article/17910729edca42d2bb94d6b5f26cec6c
Autor:
Andres Ramirez-Martinez, Bercin Kutluk Cenik, Svetlana Bezprozvannaya, Beibei Chen, Rhonda Bassel-Duby, Ning Liu, Eric N Olson
Publikováno v:
eLife, Vol 6 (2017)
Maintenance of muscle function requires assembly of contractile proteins into highly organized sarcomeres. Mutations in Kelch-like protein 41 (KLHL41) cause nemaline myopathy, a fatal muscle disorder associated with sarcomere disarray. We generated K
Externí odkaz:
https://doaj.org/article/1d10acdfe210462191f79feb0371ec27
Autor:
Rhonda Bassel-Duby, Ning Liu, Hisayuki Hashimoto, Eric N. Olson, Huanyu Zhou, Svetlana Bezprozvannaya, Glynnis A. Garry, Kenian Chen, María Gabriela Morales
Publikováno v:
Nature Cell Biology. 23:467-475
Direct cardiac reprogramming of fibroblasts to cardiomyocytes presents an attractive therapeutic strategy to restore cardiac function following injury. Cardiac reprogramming was initially achieved through overexpression of the transcription factors G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d321cdf38cc4384cfea060d5aa699c21
https://doi.org/10.1038/s41556-021-00668-z
https://doi.org/10.1038/s41556-021-00668-z
Autor:
Kenian Chen, Huanyu Zhou, Ning Liu, Glynnis A. Garry, Hisayuki Hashimoto, Svetlana Bezprozvannaya, Eric N. Olson, Rhonda Bassel-Duby
Publikováno v:
Circulation Research. 129
Ischemic heart disease is the leading cause of death worldwide. Direct reprogramming of resident cardiac fibroblasts (CFs) to induced cardiomyocytes (iCLMs) has emerged as a potential therapeutic approach to treat heart failure and ischemic disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa59987c4ae7ce1726de7b79aacc37d9
https://doi.org/10.1161/res.129.suppl_1.p493
https://doi.org/10.1161/res.129.suppl_1.p493
Autor:
John R. McAnally, Mengle Shao, Jiwoong Kim, Jessica Cannavino, Rana K. Gupta, Lin Xu, Ning Liu, Philipp E. Scherer, Eric N. Olson, Rhonda Bassel-Duby, Yu An, Shiuhwei Chen, Svetlana Bezprozvannaya
Publikováno v:
Proc Natl Acad Sci U S A
Homeothermic vertebrates produce heat in cold environments through thermogenesis, in which brown adipose tissue (BAT) increases mitochondrial oxidation along with uncoupling of the electron transport chain and activation of uncoupling protein 1 (UCP1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddcb6b460e532c0cb529465969d5561a
https://pubmed.ncbi.nlm.nih.gov/34088848
https://pubmed.ncbi.nlm.nih.gov/34088848
Autor:
John M. Shelton, Rhonda Bassel-Duby, John R. McAnally, Douglas M. Anderson, Benjamin R. Nelson, Kelly M. Anderson, Eric N. Olson, Svetlana Bezprozvannaya
Publikováno v:
Genes Dev
Myocardin, a potent coactivator of serum response factor (SRF), competes with ternary complex factor (TCF) proteins for SRF binding to balance opposing mitogenic and myogenic gene programs in cardiac and smooth muscle. Here we identify a cardiac lncR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef21ffe64d452a5a5c53c6aa20a8d7ef
https://europepmc.org/articles/PMC8168554/
https://europepmc.org/articles/PMC8168554/
Autor:
Catherine A. Makarewich, Rhonda Bassel-Duby, John R. McAnally, Svetlana Bezprozvannaya, Thomas P Matthews, Sean J. Morrison, Eric N. Olson, Misty Martin, Amir Z Munir, Aaron M. Gibson
Publikováno v:
Circulation. 142
Introduction: Emerging evidence suggests that many RNA molecules currently annotated as noncoding contain short open reading frames that code for functional small proteins called microproteins. Microproteins play critical roles in a diverse range of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::784e26504eea5d4d989de15afc92aad0
https://doi.org/10.1161/circ.142.suppl_3.16602
https://doi.org/10.1161/circ.142.suppl_3.16602