Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Svetlana B. Panina"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The C-terminal domain of RPB1 (CTD) orchestrates transcription by recruiting regulators to RNA Pol II upon phosphorylation. With CTD driving condensate formation on gene loci, the molecular mechanism behind how CTD-mediated recruitment of tr
Externí odkaz:
https://doaj.org/article/5617c07b006f4dc7b2e870a33e0063c5
Autor:
Svetlana B. Panina, Joshua V. Schweer, Qian Zhang, Gaurav Raina, Haley A. Hardtke, Seungjin Kim, Wanjie Yang, Dionicio Siegel, Y. Jessie Zhang
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background Glioblastoma (GBM) is an aggressive brain cancer associated with poor prognosis, intrinsic heterogeneity, plasticity, and therapy resistance. In some GBMs, cell proliferation is fueled by a transcriptional regulator, repressor ele
Externí odkaz:
https://doaj.org/article/b58d579647434e908a08b19c276417dd
Autor:
Rosamaria Y. Moreno, Kyle J. Juetten, Svetlana B. Panina, Jamie P. Butalewicz, Brendan M. Floyd, Mukesh Kumar Venkat Ramani, Edward M. Marcotte, Jennifer S. Brodbelt, Y. Jessie Zhang
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107581- (2023)
Summary: During eukaryotic transcription, RNA polymerase II undergoes dynamic post-translational modifications on the C-terminal domain (CTD) of the largest subunit, generating an information-rich PTM landscape that transcriptional regulators bind. T
Externí odkaz:
https://doaj.org/article/508e48fd4c6846dc911d42011f3bddbf
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-25 (2021)
Abstract Acute myeloid leukemias (AML) are a group of aggressive hematologic malignancies resulting from acquired genetic mutations in hematopoietic stem cells that affect patients of all ages. Despite decades of research, standard chemotherapy still
Externí odkaz:
https://doaj.org/article/f646a733b9bd4dca95a97fff195fe01e
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Acute myeloid leukemia (AML) is an aggressive group of cancers with high mortality rates and significant relapse risks. Current treatments are insufficient, and new therapies are needed. Recent discoveries suggest that AML may be particularly sensiti
Externí odkaz:
https://doaj.org/article/023c42a3ea0748e1b13bfb4a21fe0813
Autor:
Svetlana B. Panina, Igor V. Krolevets, Natalia P. Milyutina, Alexander B. Sagakyants, Igor V. Kornienko, Anzhelika A. Ananyan, Mikhail A. Zabrodin, Andrey A. Plotnikov, Valeriy V. Vnukov
Publikováno v:
Journal of Orthopaedics and Traumatology, Vol 18, Iss 4, Pp 349-357 (2017)
Abstract Background The identification of biomarkers of post-traumatic osteoarthritis (PTOA) progression is of clinical importance. The aims of this study were: (1) to assess the abilities of various soluble proinflammatory mediators in plasma to dis
Externí odkaz:
https://doaj.org/article/1f2c177223564e0193d72f210b0532b3
Autor:
Svetlana B. Panina, Jingqi Pei, Natalia Baran, Elissa Tjahjono, Shraddha Patel, Gheath Alatrash, Sergej Konoplev, Leonid A. Stolbov, Vladimir V. Poroikov, Marina Konopleva, Natalia V. Kirienko
Publikováno v:
Leukemia. 36(8)
Acute myeloid leukemia (AML) is a heterogeneous group of aggressive hematological malignancies commonly associated with treatment resistance, high risk of relapse, and mitochondrial dysregulation. We identified six mitochondria-affecting compounds (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d5e4d692cc1684330ce68c582024bd
https://pubmed.ncbi.nlm.nih.gov/35672446
https://pubmed.ncbi.nlm.nih.gov/35672446
Autor:
Oleg I, Kit, Dmitry I, Vodolazhsky, Natalia N, Timoshkina, Lubov' Yu, Vladimirova, Igor N, Turkin, Ksenia A, Kutsyn, Yaroslav S, Enin, Svetlana B, Panina, Vladimir, Jurisic
Publikováno v:
Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 22(6)
To assess the frequencies of somatic EGFR mutations in the tumor tissues of patients with non-small cell lung cancer (NSCLC) residing in the South of Russia (SR), and to define the relationship between genetic subtypes of NSCLC and the emergence of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f80cc1c69b80d387dcf76681be52ebd0
https://pubmed.ncbi.nlm.nih.gov/29332331
https://pubmed.ncbi.nlm.nih.gov/29332331