Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Svetlana A. Plesneva"'
Autor:
Svetlana A. Plesneva, Anthony J. Turner, Igor A. Zhuravin, Natalia N. Nalivaeva, Ekaterina G. Kochkina, Dmitrii S. Vasilev
Publikováno v:
Biogerontology. 16:473-484
Due to an increasing life expectancy in developing countries, cases of type 2 diabetes and Alzheimer’s disease (AD) in the elderly are growing exponentially. Despite a causative link between diabetes and AD, general molecular mechanisms underlying
Autor:
Ekaterina G. Kochkina, Svetlana A. Plesneva, Igor A. Zhuravin, Anthony J. Turner, Natalia N. Nalivaeva
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 51:107-116
This study reports the dynamics of changes in postnatal ontogenesis of the activity of soluble and membrane-bound forms of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) in the sensorimotor cortex of rats as well as the character of the
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 50:399-408
The functional state of adenylyl cyclase signaling system (ACSS) and its regulation by the hormones and the inhibitor of adenylyl cyclase (AC), somatostatine (SST), in the brain and myocardium and by 5-nonyloxytryptamine (5-NOT) in the brain of rats
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 49:145-152
In the smooth muscles of mollusc Anodonta cygnea the regulatory action of hormones on adenylyl cyclase signaling system (ACSS) are realized through the receptors of serpentine type (biogenic amines, isoproterenol, glucagon) and receptor tyrosine kina
Changes in the Activity of Amyloid-Degrading Metallopeptidases Leads to Disruption of Memory in Rats
Autor:
Anthony J. Turner, A. A. Feponova, N. M. Dubrovskaya, Natalia N. Nalivaeva, Igor A. Zhuravin, Svetlana A. Plesneva
Publikováno v:
Neuroscience and Behavioral Physiology. 40:975-980
In old male Wistar rats (older than 12 months), or adult males (3–4 months) subjected to prenatal hypoxia (7% O2, 3 h, E14), a disruption of short-term memory was observed. Prenatal hypoxia also led to a decrease in the brain cortex of the levels o
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 44:542-551
Based on the earlier discovered by the authors adenylyl cyclase signaling mechanisms (ACSM) of action of insulin and relaxin, a study was performed of the existence of a similar action mechanism of another representative of the insulin superfamily-th
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 44:552-561
It has been shown for the first time that biogenic amines (catecholamines and tryptophane derivatives) stimulate dose-dependently activity of adenylyl cyclase (AC) and GTP-binding of G-proteins in muscle of the skin-muscle sac of the earthworm Lumbri
Publikováno v:
Journal of Neurochemistry. 81:9-13
By studying the effects of gangliosides (G) on learning and memory we have found that i.p. administration of G led to a decrease in AC activity in the cortex (Cx) and striatum (Str) as well as in the threshold of the sensitivity of striatal neurons t
Publikováno v:
Doklady Biochemistry and Biophysics. 417:316-319
Autor:
O. V. Chistyakova, A. O. Shpakov, Vera M. Bondareva, M. N. Pertseva, L. A. Kuznetsova, Svetlana A. Plesneva
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 43:548-556
In terms of development of evolutionary biomedicine using invertebrate animals as models for study of molecular grounds of various human diseases, for the first time the streptozotocin (ST) model of insulin-dependent diabetes in the mollusc Anodonta