Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Svetlana A. Appolonova"'
Publikováno v:
Клинический разбор в общей медицине, Vol 5, Iss 4, Pp 76-82 (2024)
Background. Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by progressive joint damage and leading to early disability in patients. The main purpose of its treatment is to alleviate the pain caused by the disease, de
Externí odkaz:
https://doaj.org/article/4e56ba0e145845279baa1e4a29024894
Autor:
Sergey Girel, Pavel A. Markin, Elena Tobolkina, Julien Boccard, Natalia E. Moskaleva, Serge Rudaz, Svetlana A. Appolonova
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The steroid submetabolome, or steroidome, is of particular interest in prostate cancer (PCa) as the dependence of PCa growth on androgens is well known and has been routinely exploited in treatment for decades. Nevertheless, the community is
Externí odkaz:
https://doaj.org/article/321e2f0df9584834938de30f327ef8cf
Autor:
Iosif B. Mikhel, Elena O. Bakhrushina, Danila A. Petrusevich, Andrey A. Nedorubov, Svetlana A. Appolonova, Natalia E. Moskaleva, Natalia B. Demina, Svetlana I. Kosenkova, Mikhail A. Parshenkov, Ivan I. Krasnyuk
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1125 (2024)
Recently, ribavirin has demonstrated effectiveness in treating glioblastoma through intranasal administration utilizing the nose-to-brain delivery route. Enhancing ribavirin’s bioavailability can be achieved by utilizing intranasal stimuli-responsi
Externí odkaz:
https://doaj.org/article/21faad652b6d403e958ace4327e26340
Targeted metabolomic profiling as a tool for diagnostics of patients with non-small-cell lung cancer
Autor:
Ksenia M. Shestakova, Natalia E. Moskaleva, Andrey A. Boldin, Pavel M. Rezvanov, Alexandr V. Shestopalov, Sergey A. Rumyantsev, Elena Yu. Zlatnik, Inna A. Novikova, Alexander B. Sagakyants, Sofya V. Timofeeva, Yuriy Simonov, Sabina N. Baskhanova, Elena Tobolkina, Serge Rudaz, Svetlana A. Appolonova
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Lung cancer is referred to as the second most common cancer worldwide and is mainly associated with complex diagnostics and the absence of personalized therapy. Metabolomics may provide significant insights into the improvement of lung cance
Externí odkaz:
https://doaj.org/article/aaab72de8a6349c2873076e710e43142
Autor:
Yuri N. Belenkov, Anton A. Ageev, Maria V. Kozhevnikova, Natalia V. Khabarova, Anastasia V. Krivova, Ekaterina O. Korobkova, Ludmila V. Popova, Alexey V. Emelyanov, Svetlana A. Appolonova, Natalia E. Moskaleva, Ksenia M. Shestakova, Elena V. Privalova
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 10, p 438 (2023)
Background: Progressive myocardial remodeling (MR) in chronic heart failure (CHF) leads to aggravation of systolic dysfunction (SD) and clinical manifestations. Identification of metabolomic markers of these processes may help in the search for new t
Externí odkaz:
https://doaj.org/article/c673383692a64fe28a764eec466c4fee
Autor:
Anastasia A. Zabolotneva, Andrei M. Gaponov, Sergey A. Roumiantsev, Ilya Yu. Vasiliev, Tatiana V. Grigoryeva, Oleg I. Kit, Elena Yu. Zlatnik, Aleksey Yu. Maksimov, Anna S. Goncharova, Inna A. Novikova, Svetlana A. Appolonova, Pavel A. Markin, Aleksandr V. Shestopalov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14206 (2023)
Alkylresorcinols (ARs) are polyphenolic compounds with a wide spectrum of biological activities and are potentially involved in the regulation of host metabolism. The present study aims to establish whether ARs can be produced by the human gut microb
Externí odkaz:
https://doaj.org/article/f4d15e1570e44503a429ba397d3e8d30
Autor:
Aleksandr V. Shestopalov, Oleg I. Kit, Anastasia A. Zabolotneva, Elena Y. Zlatnik, Aleksey Yu Maksimov, Inna A. Novikova, Alexander B. Sagakyants, Sofya V. Timofeeva, Anna S. Goncharova, Anastasia V. Galina, Svetlana A. Appolonova, Pavel A. Markin, Valentin V. Makarov, Sergey M. Yudin, Anton A. Keskinov, Sergei A. Roumiantsev, Oleg I. Meshkov
Publikováno v:
Advanced Gut & Microbiome Research, Vol 2023 (2023)
Background. Alkylresorcinols (ARs) are polyphenolic compounds of microbial origin with a wide spectrum of biological activities and are potentially involved in host immune functioning. The present study is aimed at evaluating alterations in AR conten
Externí odkaz:
https://doaj.org/article/8b2cdd81a5ab46e097fd3fe45df3eefd
Autor:
Natalia E. Moskaleva, Ksenia M. Shestakova, Alexey V. Kukharenko, Pavel A. Markin, Maria V. Kozhevnikova, Ekaterina O. Korobkova, Alex Brito, Sabina N. Baskhanova, Natalia V. Mesonzhnik, Yuri N. Belenkov, Natalia V. Pyatigorskaya, Elena Tobolkina, Serge Rudaz, Svetlana A. Appolonova
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1185 (2022)
Metabolomics is a promising technology for the application of translational medicine to cardiovascular risk. Here, we applied a liquid chromatography/tandem mass spectrometry approach to explore the associations between plasma concentrations of amino
Externí odkaz:
https://doaj.org/article/0fa854bc4ef940a3ac580963c35b98a7
Autor:
Ksenia M. Shestakova, Natalia V. Mesonzhnik, Pavel A. Markin, Natalia E. Moskaleva, Andrey A. Nedorubov, Alex Brito, Elizaveta G. Appolonova, Roman M. Kuznetsov, Natalia L. Bochkareva, Alexey Kukharenko, Alexey V. Lyundup, Franco Tagliaro, Svetlana A. Appolonova
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 668 (2021)
The strong psychoactive effects of synthetic cannabinoids raise the need for the deeper studying of their neurometabolic effects. The pharmacokinetic properties of 5F-APINAC and its influence on metabolomics profiles associated with neurotransmission
Externí odkaz:
https://doaj.org/article/e670fa7c40154b3781590e1deecd1621
Autor:
Ksenia M. Shestakova, Natalia E. Moskaleva, Natalia V. Mesonzhnik, Alexey V. Kukharenko, Igor V. Serkov, Igor I. Lyubimov, Elena V. Fomina-Ageeva, Vladimir V. Bezuglov, Mikhail G. Akimov, Svetlana A. Appolonova
Publikováno v:
Molecules, Vol 25, Iss 24, p 5896 (2020)
Prostanit is a novel drug developed for the treatment of peripheral arterial diseases. It consists of a prostaglandin E1 (PGE1) moiety with two nitric oxide (NO) donor fragments, which provide a combined vasodilation effect on smooth muscles and vasc
Externí odkaz:
https://doaj.org/article/69472e20970247caa7915ac4d6983d84