Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Svetlana A Golovko"'
Autor:
Sema Oncel, Qinggang Wang, Ahmed Adham R Elsayed, Emilie E Vomhof-DeKrey, Nicholas D Brown, Mikhail Y Golovko, Svetlana A Golovko, Ricardo Gallardo-Macias, Vadim J Gurvich, Marc D Basson
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0304010 (2024)
M64HCl, which has drug-like properties, is a water-soluble Focal Adhesion Kinase (FAK) activator that promotes murine mucosal healing after ischemic or NSAID-induced injury. Since M64HCl has a short plasma half-life in vivo (less than two hours), it
Externí odkaz:
https://doaj.org/article/eaf4a03f8e64424fb7b4fef3415f9b94
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Recently, we have reported a novel neuronal specific pathway for adaptation to hypoxia through increased fatty acid (FA) biosynthesis (FAS) followed by esterification into lipids. However, the biological role of this pathway under hypoxia remains to
Externí odkaz:
https://doaj.org/article/6ef32007c94f451ba320ba7f1382f22d
Autor:
Qinggang Wang, Ricardo Gallardo-Macias, Emilie E. Vomhof-DeKrey, Rashmi Gupta, Svetlana A. Golovko, Mikhail Y. Golovko, Sema Oncel, Vadim J. Gurvich, Marc D. Basson
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 4, Iss , Pp 100147- (2023)
Non-steroidal anti-inflammatory drugs (NSAIDs) injure the proximal and distal gut by different mechanisms. While many drugs reduce gastrointestinal injury, no drug directly stimulates mucosal wound healing. Focal adhesion kinase (FAK), a non-receptor
Externí odkaz:
https://doaj.org/article/d0e700f3f0f94c29b62d9ab5274beecb
Autor:
Kaitlyn S. Campbell, Peyton Keller, Svetlana A. Golovko, Drew Seeger, Mikhail Y. Golovko, Jacob L. Kerby
Publikováno v:
Environmental Science & Technology. 57:2758-2767
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f883fe932ab1560b2d6eea921e2dad51
https://doi.org/10.1021/acs.est.2c06527
https://doi.org/10.1021/acs.est.2c06527
Autor:
Iryna A, Khasabova, Jacob, Gable, Malcolm, Johns, Sergey G, Khasabov, Alexander E, Kalyuzhny, Mikhail Y, Golovko, Svetlana A, Golovko, Stacy, Kiven, Kalpna, Gupta, Virginia S, Seybold, Donald A, Simone
Publikováno v:
Haematologica. 108:859-869
Sickle cell disease (SCD) is the most common inherited disease. Pain is a key morbidity of SCD and opioids are the main treatment but their side effects emphasize the need for new analgesic approaches. Humanized transgenic mouse models have been inst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e400051e413d66de1b722f75b00568
https://doi.org/10.3324/haematol.2021.280460
https://doi.org/10.3324/haematol.2021.280460
Autor:
Ali Alinezhad, Pavankumar Challa Sasi, Ping Zhang, Bin Yao, Alena Kubátová, Svetlana A. Golovko, Mikhail Y. Golovko, Feng Xiao
Publikováno v:
ACS ES&T Engineering. 2:198-209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b604355285a5629649ddb874602e3b1
https://doi.org/10.1021/acsestengg.1c00335
https://doi.org/10.1021/acsestengg.1c00335
Autor:
Iryna I. Khasabova, Joseph Juliette, Victoria M. Rogness, Sergey G. Khasabov, Mikhail Y. Golovko, Svetlana A. Golovko, Stacy Kiven, Kalpna Gupta, John D. Belcher, Gregory M. Vercellotti, Virginia S. Seybold, Donald A. Simone
Publikováno v:
Blood. 140(16)
In order to better understand mechanisms underlying acute pain during vaso-occlusive crises (VOCs) in patients with sickle cell disease, Khasabova et al report on a clinically relevant model in mice where VOC is stimulated by exposure to cold. Cold e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf74be60d0e81aa7d516729770bd64b
https://pubmed.ncbi.nlm.nih.gov/35960856
https://pubmed.ncbi.nlm.nih.gov/35960856
Autor:
Diane C. Darland, Colin K. Combs, Harpreet Kaur, Surjeet Singh, Svetlana A. Golovko, Mikhail Y. Golovko
Publikováno v:
Journal of Alzheimer's Disease. 76:1083-1102
Background: The intestinal microbiota and its metabolites, particularly short-chain fatty acids (SCFAs), have been implicated in immune function, host metabolism, and even behavior. Objective: This study was performed to investigate whether probiotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09301e78f092fadd2cb7435d5ea47a2f
https://doi.org/10.3233/jad-200436
https://doi.org/10.3233/jad-200436
Autor:
Kumi Nagamoto-Combs, Harpreet Kaur, Mikhail Y. Golovko, Svetlana A. Golovko, Marilyn G. Klug, Colin K. Combs
Publikováno v:
Neurobiol Aging
Evidence suggests that changes in intestinal microbiota may not only influence gastrointestinal function but also affect the central nervous system (CNS). However, it is unclear whether alteration of the intestinal microbiota affects progression or i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2bfdafaa2a4fb334d668eb29d5d807d
https://doi.org/10.1016/j.neurobiolaging.2020.04.009
https://doi.org/10.1016/j.neurobiolaging.2020.04.009
Publikováno v:
Environmental Science & Technology. 54:7378-7387
Perfluorooctanoate (PFOA) and perfluorooctanesulfonate (PFOS) are two environmentally persistent per- and polyfluoroalkyl substances (PFAS) that have been detected globally in human tissues and fluids. As part of a project investigating the indirect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::138a53a977fa7ea20ef53323cd5dfa54
https://doi.org/10.1021/acs.est.0c01644
https://doi.org/10.1021/acs.est.0c01644