Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Svetlana A Golovko"'
Autor:
Derek Besch, Drew R. Seeger, Brennon Schofield, Svetlana A. Golovko, Meredith Parmer, Mikhail Y. Golovko
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 7, Pp 100583- (2024)
Dramatic postmortem prostanoid (PG) enzymatic synthesis in the brain causes a significant artifact during PG analysis. Thus, enzyme deactivation is required for an accurate in situ endogenous PG quantification. To date, the only method for preventing
Externí odkaz:
https://doaj.org/article/7ec5587d89cc472796beff42a0b10d23
Autor:
Brett A. McGregor, Elham Razmjou, Hossein Hooshyar, Drew R. Seeger, Svetlana A. Golovko, Mikhail Y. Golovko, Steven M. Singer, Junguk Hur, Shahram Solaymani-Mohammadi
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-19 (2023)
Abstract Background The mechanisms underlying the clinical outcome disparity during human infection with Giardia duodenalis are still unclear. In recent years, evidence has pointed to the roles of host factors as well as parasite’s genetic heteroge
Externí odkaz:
https://doaj.org/article/95b79fddc8524a69b6e268fa44451f35
Autor:
Sema Oncel, Qinggang Wang, Ahmed Adham R Elsayed, Emilie E Vomhof-DeKrey, Nicholas D Brown, Mikhail Y Golovko, Svetlana A Golovko, Ricardo Gallardo-Macias, Vadim J Gurvich, Marc D Basson
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0304010 (2024)
M64HCl, which has drug-like properties, is a water-soluble Focal Adhesion Kinase (FAK) activator that promotes murine mucosal healing after ischemic or NSAID-induced injury. Since M64HCl has a short plasma half-life in vivo (less than two hours), it
Externí odkaz:
https://doaj.org/article/eaf4a03f8e64424fb7b4fef3415f9b94
Autor:
Drew R. Seeger, Brennon Schofield, Derek Besch, Svetlana A. Golovko, Peddanna Kotha, Meredith Parmer, Shahram Solaymani-Mohammadi, Mikhail Y. Golovko
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 11, Pp 100452- (2023)
Previously, we and others reported a rapid and dramatic increase in brain prostanoids (PG), including prostaglandins, prostacyclins, and thromboxanes, under ischemia that is traditionally explained through the activation of esterified arachidonic aci
Externí odkaz:
https://doaj.org/article/05757f17b6e94829ae02f7e9e56a72e9
Autor:
Qinggang Wang, Ricardo Gallardo-Macias, Emilie E. Vomhof-DeKrey, Rashmi Gupta, Svetlana A. Golovko, Mikhail Y. Golovko, Sema Oncel, Vadim J. Gurvich, Marc D. Basson
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 4, Iss , Pp 100147- (2023)
Non-steroidal anti-inflammatory drugs (NSAIDs) injure the proximal and distal gut by different mechanisms. While many drugs reduce gastrointestinal injury, no drug directly stimulates mucosal wound healing. Focal adhesion kinase (FAK), a non-receptor
Externí odkaz:
https://doaj.org/article/d0e700f3f0f94c29b62d9ab5274beecb
Autor:
Iryna A. Khasabova, Jacob Gable, Malcolm Johns, Sergey G. Khasabov, Alexander E. Kalyuzhny, Mikhail Y. Golovko, Svetlana A. Golovko, Stacy Kiven, Kalpna Gupta, Virginia S. Seybold, Donald A. Simone
Publikováno v:
Haematologica, Vol 108, Iss 3 (2022)
Sickle cell disease (SCD) is the most common inherited disease. Pain is a key morbidity of SCD and opioids are the main treatment but their side effects emphasize the need for new analgesic approaches. Humanized transgenic mouse models have been inst
Externí odkaz:
https://doaj.org/article/d52cf4b8931e4d4a97173e7e6f955e02
Autor:
Kaitlyn S. Campbell, Peyton Keller, Svetlana A. Golovko, Drew Seeger, Mikhail Y. Golovko, Jacob L. Kerby
Publikováno v:
Environmental Science & Technology. 57:2758-2767
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f883fe932ab1560b2d6eea921e2dad51
https://doi.org/10.1021/acs.est.2c06527
https://doi.org/10.1021/acs.est.2c06527
Autor:
Ali Alinezhad, Pavankumar Challa Sasi, Ping Zhang, Bin Yao, Alena Kubátová, Svetlana A. Golovko, Mikhail Y. Golovko, Feng Xiao
Publikováno v:
ACS ES&T Engineering. 2:198-209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b604355285a5629649ddb874602e3b1
https://doi.org/10.1021/acsestengg.1c00335
https://doi.org/10.1021/acsestengg.1c00335
Autor:
Iryna I. Khasabova, Joseph Juliette, Victoria M. Rogness, Sergey G. Khasabov, Mikhail Y. Golovko, Svetlana A. Golovko, Stacy Kiven, Kalpna Gupta, John D. Belcher, Gregory M. Vercellotti, Virginia S. Seybold, Donald A. Simone
Publikováno v:
Blood. 140(16)
In order to better understand mechanisms underlying acute pain during vaso-occlusive crises (VOCs) in patients with sickle cell disease, Khasabova et al report on a clinically relevant model in mice where VOC is stimulated by exposure to cold. Cold e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf74be60d0e81aa7d516729770bd64b
https://pubmed.ncbi.nlm.nih.gov/35960856
https://pubmed.ncbi.nlm.nih.gov/35960856
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Recently, we have reported a novel neuronal specific pathway for adaptation to hypoxia through increased fatty acid (FA) biosynthesis (FAS) followed by esterification into lipids. However, the biological role of this pathway under hypoxia remains to
Externí odkaz:
https://doaj.org/article/6ef32007c94f451ba320ba7f1382f22d