Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Svetlana Ghimbovschi"'
Autor:
Hayriye Verda Erkizan, Kory Johnson, Svetlana Ghimbovschi, Deepa Karkera, Gregory Trachiotis, Houtan Adib, Eric P. Hoffman, Robert G. Wadleigh
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)
Abstract Background Esophageal carcinoma is the third most common gastrointestinal malignancy worldwide and is largely unresponsive to therapy. African-Americans have an increased risk for esophageal squamous cell carcinoma (ESCC), the subtype that s
Externí odkaz:
https://doaj.org/article/7ab688e390594178ab1dd5d0310cf450
Autor:
Anne Bigot, William J. Duddy, Zamalou G. Ouandaogo, Elisa Negroni, Virginie Mariot, Svetlana Ghimbovschi, Brennan Harmon, Aurore Wielgosik, Camille Loiseau, Joe Devaney, Julie Dumonceaux, Gillian Butler-Browne, Vincent Mouly, Stéphanie Duguez
Publikováno v:
Cell Reports, Vol 13, Iss 6, Pp 1172-1182 (2015)
The molecular mechanisms by which aging affects stem cell number and function are poorly understood. Murine data have implicated cellular senescence in the loss of muscle stem cells with aging. Here, using human cells and by carrying out experiments
Externí odkaz:
https://doaj.org/article/7f96e260906c4120a8bf5bab9bf674c7
Effect of endurance exercise on microRNAs in myositis skeletal muscle-A randomized controlled study.
Autor:
Jessica F Boehler, Marshall W Hogarth, Matthew D Barberio, James S Novak, Svetlana Ghimbovschi, Kristy J Brown, Li Alemo Munters, Ingela Loell, Yi-Wen Chen, Heather Gordish-Dressman, Helene Alexanderson, Ingrid E Lundberg, Kanneboyina Nagaraju
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183292 (2017)
To identify changes in skeletal muscle microRNA expression after endurance exercise and associate the identified microRNAs with mRNA and protein expression to disease-specific pathways in polymyositis (PM) and dermatomyositis (DM) patients.Following
Externí odkaz:
https://doaj.org/article/d90075eef8b740c6bdb09916a05214c1
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134827 (2015)
Exposure to high dose radiation in combination with physical injuries such as burn or wound trauma can produce a more harmful set of medical complications requiring specialist interventions. Currently these interventions are unavailable as are the pr
Externí odkaz:
https://doaj.org/article/0424a4f72df247d2a831284d5b247e7c
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72258 (2013)
Individuals who rapidly develop hyperthermia during heat exposure (heat-intolerant) are vulnerable to heat associated illness and injury. We recently reported that heat intolerant mice exhibit complex alterations in stress proteins in response to hea
Externí odkaz:
https://doaj.org/article/47b7e327f13140f483805207aa1401b7
Autor:
Gregory D. Trachiotis, Eric P. Hoffman, Svetlana Ghimbovschi, Kory Johnson, Robert G. Wadleigh, Houtan Adib, Deepa J. Karkera, Hayriye V. Erkizan
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)
BMC Cancer
BMC Cancer
Background Esophageal carcinoma is the third most common gastrointestinal malignancy worldwide and is largely unresponsive to therapy. African-Americans have an increased risk for esophageal squamous cell carcinoma (ESCC), the subtype that shows mark
Autor:
Adam Horn, Ning Li, James S. Novak, Li Alemo Munters, Svetlana Ghimbovschi, Helene Alexanderson, Ingrid E. Lundberg, Kanneboyina Nagaraju, Jessica F. Boehler, Jyoti K. Jaiswal
Publikováno v:
J Pathol
The etiology of myositis is unknown. Although attempts to identify viruses in myositis skeletal muscle have failed, several studies have identified the presence of a viral signature in myositis patients. Here we postulate that in individuals with sus
Autor:
Aditi Phadke, Lisa G. Rider, Eric P. Hoffman, Sree Rayavarapu, Kanneboyina Nagaraju, Frederick W. Miller, Svetlana Ghimbovschi
Publikováno v:
Rheumatology. 55:1673-1680
Objective To identify muscle gene expression patterns that predict rituximab responses and assess the effects of rituximab on muscle gene expression in PM and DM. Methods In an attempt to understand the molecular mechanism of response and non-respons
Autor:
Christopher A. Loffredo, Eva Sovcikova, Sisir K. Dutta, Eric P. Hoffman, Partha S. Mitra, Tomas Trnovec, Lubica Palkovicova Murinova, Somiranjan Ghosh, Svetlana Ghimbovschi, Shizhu Zang
Publikováno v:
Environmental Research. 138:202-216
Background and aims Our earlier gene-expression studies with a Slovak PCBs-exposed population have revealed possible disease and disorder development in accordance with epidemiological studies. The present investigation aimed to develop an in vitro m
Autor:
Susan Knoblach, Angèle Nalbandian, Katrina J. Llewellyn, Svetlana Ghimbovschi, M.R.C.P. Virginia E. Kimonis M.D., Eric P. Hoffman, Zuyi Wang, Jouni Vesa
Publikováno v:
Clinical and Translational Science. 8:8-16
Dominant mutations in the valosin-containing protein (VCP) gene cause inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia, which is characterized by progressive muscle weakness, dysfunction in bone remodeling, an