Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Svetlana, Radaeva"'
Autor:
Wanzhu Tu, Samer Gawrieh, Srinivasan Dasarathy, Mack C. Mitchell, Douglas A. Simonetto, Kavish R. Patidar, Craig J. McClain, Ramon Bataller, Gyongyi Szabo, Qing Tang, Bruce A. Barton, Svetlana Radaeva, Arun J. Sanyal, Vijay Shah
Publikováno v:
Contemporary Clinical Trials Communications, Vol 32, Iss , Pp 101074- (2023)
Background: Mortality is high for severe alcohol-associated hepatitis (AH). Corticosteroids are the standard of care for patients without contraindications. Recent data showed that interleukin-1β receptor antagonist anakinra attenuated inflammation
Externí odkaz:
https://doaj.org/article/4203b99fa20a49bd8563292dfc456ba2
Autor:
Tatsunori Miyata, Xiaoqin Wu, Xiude Fan, Emily Huang, Carlos Sanz-Garcia, Christina K. Cajigas-Du Ross, Sanjoy Roychowdhury, Annette Bellar, Megan R. McMullen, Jaividhya Dasarathy, Daniela S. Allende, Joan Caballeria, Pau Sancho-Bru, Craig J. McClain, Mack Mitchell, Arthur J. McCullough, Svetlana Radaeva, Bruce Barton, Gyongyi Szabo, Srinivasan Dasarathy, Laura E. Nagy
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
Externí odkaz:
https://doaj.org/article/62602ca604e54c7997de01962de6b453
Autor:
Robert N Helsley, Tatsunori Miyata, Anagha Kadam, Venkateshwari Varadharajan, Naseer Sangwan, Emily C Huang, Rakhee Banerjee, Amanda L Brown, Kevin K Fung, William J Massey, Chase Neumann, Danny Orabi, Lucas J Osborn, Rebecca C Schugar, Megan R McMullen, Annette Bellar, Kyle L Poulsen, Adam Kim, Vai Pathak, Marko Mrdjen, James T Anderson, Belinda Willard, Craig J McClain, Mack Mitchell, Arthur J McCullough, Svetlana Radaeva, Bruce Barton, Gyongyi Szabo, Srinivasan Dasarathy, Jose Carlos Garcia-Garcia, Daniel M Rotroff, Daniela S Allende, Zeneng Wang, Stanley L Hazen, Laura E Nagy, Jonathan Mark Brown
Publikováno v:
eLife, Vol 11 (2022)
There is mounting evidence that microbes residing in the human intestine contribute to diverse alcohol-associated liver diseases (ALD) including the most deadly form known as alcohol-associated hepatitis (AH). However, mechanisms by which gut microbe
Externí odkaz:
https://doaj.org/article/9d2e1ecd214249d6a556320886d84ab0
Autor:
Tatsunori Miyata, Xiaoqin Wu, Xiude Fan, Emily Huang, Carlos Sanz-Garcia, Christina K. Cajigas-Du Ross, Sanjoy Roychowdhury, Annette Bellar, Megan R. McMullen, Jaividhya Dasarathy, Daniela S. Allende, Joan Caballeria, Pau Sancho-Bru, Craig J. McClain, Mack Mitchell, Arthur J. McCullough, Svetlana Radaeva, Bruce Barton, Gyongyi Szabo, Srinivasan Dasarathy, Laura E. Nagy
Publikováno v:
JCI Insight, Vol 6, Iss 4 (2021)
Hepatocellular death contributes to progression of alcohol–associated (ALD-associated) and non–alcohol-associated (NAFL/NASH) liver diseases. However, receptor-interaction protein kinase 3 (RIP3), an intermediate in necroptotic cell death, contri
Externí odkaz:
https://doaj.org/article/4b33e988829949079db41f2bdafd029c
Autor:
Spencer Lourens, PhD, Dharma B. Sunjaya, MD, Ashwani Singal, MD, Suthat Liangpunsakul, MD, MPH, Puneet Puri, MD, Arun Sanyal, MD, Xiaowei Ren, MS, Gregory J. Gores, MD, Svetlana Radaeva, PhD, Naga Chalasani, MD, David W. Crabb, MD, Barry Katz, PhD, Patrick S. Kamath, MD, Vijay H. Shah, MD, David Crabb, MD, Suthat Liangpunsakul, MD, Andy Borst, BS, Ryan Cook, MPH, Andy Qigui Yu, PhD, David Nelson, PhD, Romil Saxena, MD, Sherrie Cummings, RN, Megan Comerford, BS, Lakye Edwards, BS, Gregory Gores, MD, Vikas Verma, PhD, Sarah Wilder, RN, BSN, Amy Olofson, RN, Amanda Schimek, Susan Walker, RN, MSN, Andras Orosz, PhD
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 1, Iss 1, Pp 37-48 (2017)
Objective: To examine the natural history of acute alcoholic hepatitis (AH) and identify predictors of mortality for AH using data from a prospective multicenter observational study. Participants and Methods: We analyzed data from 164 patients with A
Externí odkaz:
https://doaj.org/article/5e1a75153a4e49429bcb0c1b9f760fd1
Autor:
Vatsalya Vatsalya, Wenke Feng, Maiying Kong, Huirong Hu, Gyongyi Szabo, Arthur McCullough, Srinivasan Dasarathy, Laura E. Nagy, Svetlana Radaeva, Bruce Barton, Mack Mitchell, Craig J. McClain
Publikováno v:
American Journal of Gastroenterology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e02407b02c36ddc3a7d1d95f2158e608
https://doi.org/10.14309/ajg.0000000000002283
https://doi.org/10.14309/ajg.0000000000002283
Autor:
Marcelle de Carvalho Ribeiro, Arvin Iracheta-Vellve, Mrigya Babuta, Charles D. Calenda, Christopher Copeland, Yuan Zhuang, Patrick P. Lowe, Danielle Hawryluk, Donna Catalano, Yeonhee Cho, Bruce Barton, Srinivasan Dasarathy, Craig McClain, Arthur McCullough, Mack Mitchell, Laura E. Nagy, Svetlana Radaeva, Egil Lien, Douglas T. Golenbock, Gyongyi Szabo
Publikováno v:
Hepatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee4a257b036a4b321d3e2e651b172b37
https://doi.org/10.1097/hep.0000000000000298
https://doi.org/10.1097/hep.0000000000000298
Autor:
Gyongyi Szabo, Mack Mitchell, Craig J. McClain, Srinivasan Dasarathy, Bruce Barton, Arthur J. McCullough, Laura E. Nagy, Aimee Kroll‐Desrosiers, David Tornai, Hyesung Alice Min, Svetlana Radaeva, M. E. Blair Holbein, Lisa Casey, Jennifer Cuthbert
Publikováno v:
Hepatology (Baltimore, Md.)REFERENCES. 76(4)
Patients with severe alcohol-associated hepatitis (AH) have high mortality. Corticosteroids improve survival only for 30 days. We targeted inflammation, cellular injury, and gut leakiness in a randomized clinical trial comparing combination therapy t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab1d1d55e5d06a1574dfff846921506
https://pubmed.ncbi.nlm.nih.gov/35776666
https://pubmed.ncbi.nlm.nih.gov/35776666
Autor:
Emily Huang, Gyongyi Szabo, Mack C. Mitchell, Kyle L. Poulsen, Bruce A. Barton, Arthur J. McCullough, Rebecca L. McCullough, Daniel M. Rotroff, Srinivasan Dasarathy, Annette Bellar, Laura E. Nagy, Adam Kim, Craig J. McClain, Xiude Fan, Svetlana Radaeva
Publikováno v:
Hepatology
Background and aims Given the lack of effective therapies and high mortality in acute alcohol-associated hepatitis (AH), it is important to develop rationally designed biomarkers for effective disease management. Complement, a critical component of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3960fec0fb165211a1084b2a3a77fd2
https://doi.org/10.1002/hep.31419
https://doi.org/10.1002/hep.31419
Autor:
Leila Gobejishvili, Vatsalya Vatsalya, Svetlana Radaeva, Matthew C. Cave, Arthur J. McCullough, K. Cameron Falkner, Bruce A. Barton, Gyongyi Szabo, Craig J. McClain, Maiying Kong, John Craycroft, Mack C. Mitchell, Srinivasan Dasarathy
Publikováno v:
Clin Gastroenterol Hepatol
Background & Aims Acute alcoholic hepatitis (AAH) is a major cause of liver-related morbidity and mortality; there are no good blood biomarkers for diagnosis or determining magnitude of cell death. Keratin 18 (KRT18, also called K18), found in epithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7ae27a5c5d6b4ce2e444dc094d2b6b
https://doi.org/10.1016/j.cgh.2019.11.050
https://doi.org/10.1016/j.cgh.2019.11.050