Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Svetla Stoilova‐McPhie"'
Autor:
Girgis Obaid, Shazia Bano, Hanna Thomsen, Susan Callaghan, Nimit Shah, Joseph W. R. Swain, Wendong Jin, Xiadong Ding, Colin G. Cameron, Sherri A. McFarland, Juwell Wu, Mark Vangel, Svetla Stoilova‐McPhie, Jie Zhao, Mari Mino‐Kenudson, Charles Lin, Tayyaba Hasan
Publikováno v:
Advanced Science, Vol 9, Iss 24, Pp n/a-n/a (2022)
Abstract Desmoplasia is characteristic of pancreatic ductal adenocarcinoma (PDAC), which exhibits 5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that contribute to treatment resistance, yet depleting the stroma
Externí odkaz:
https://doaj.org/article/0670866fd506442c8ba84eb912ca8dbe
Autor:
Elka R. Georgieva, Peter P. Borbat, Kirill Grushin, Svetla Stoilova-McPhie, Nichita J. Kulkarni, Zhichun Liang, Jack H. Freed
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
The M2 protein from influenza A plays important roles in its viral cycle. It contains a single transmembrane helix, which oligomerizes into a homotetrameric proton channel that conducts in the low-pH environment of the host-cell endosome and Golgi ap
Externí odkaz:
https://doaj.org/article/342ed16b938a4175b60805e963dbb617
Autor:
Svetla Stoilova-McPhie
Publikováno v:
Subcellular Biochemistry ISBN: 9783030589707
The formation of membrane-bound complexes between specific coagulation factors at different cell surfaces is required for effective blood clotting. The most important of these complexes, the intrinsic Tenase and Prothrombinase complexes, are formed o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dac0017d1bf8997809b68961683a90d
https://doi.org/10.1007/978-3-030-58971-4_2
https://doi.org/10.1007/978-3-030-58971-4_2
Autor:
Svetla, Stoilova-McPhie
Publikováno v:
Sub-cellular biochemistry. 96
The formation of membrane-bound complexes between specific coagulation factors at different cell surfaces is required for effective blood clotting. The most important of these complexes, the intrinsic Tenase and Prothrombinase complexes, are formed o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e44a974b394cd06e3181fe543843708
https://pubmed.ncbi.nlm.nih.gov/33252728
https://pubmed.ncbi.nlm.nih.gov/33252728
Autor:
Daniel Finley, Youdong Mao, Svetla Stoilova-McPhie, Zhaolong Wu, Yuanchen Dong, Ying Lu, Yanan Zhu, Xuemei Li, Wei Li Wang, Shuwen Zhang
Publikováno v:
Nature
The proteasome is an ATP-dependent, 2.5-megadalton molecular machine that is responsible for selective protein degradation in eukaryotic cells. Here we present cryo-electron microscopy structures of the substrate-engaged human proteasome in seven con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db638cbe918587d04eeb7eff943191d2
https://doi.org/10.1038/s41586-018-0736-4
https://doi.org/10.1038/s41586-018-0736-4
Publikováno v:
Nanotechnology Reviews. 6:139-148
Nanodiscs (ND) are discoidal phospholipid bilayers stabilized by a pair of membrane-scaffolding proteins (MSP). The macromolecular composition and size of ND are ideal for structural and functional studies of membrane and membrane-associated proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::065837dbfde70425b6f4cad18ed31bc1
https://doi.org/10.1515/ntrev-2016-0073
https://doi.org/10.1515/ntrev-2016-0073
Autor:
Youdong Mao, Daniel Finley, Xuemei Li, Yuanchen Dong, Zhaolong Wu, Svetla Stoilova-McPhie, Ying Lu, Yanan Zhu, Wei Li Wang, Shuwen Zhang
The proteasome is an ATP-dependent 2.5-megadalton machine responsible for ubiquitylated protein degradation in all eukaryotic cells. Here we present cryo-EM structures of the substrate-engaged human 26S proteasome in seven conformational states at 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb5513c3ee824fdebe009d9073be589
Autor:
Flavia Damiani, Philip Demokritou, Svetla Stoilova-McPhie, Ramon M. Molina, Thomas C. Donaghey, Jason S. Tresback, Georgios Pyrgiotakis, Joseph D. Brain, Nagarjun V. Konduru
We explored the influence of nanoparticle (NP) surface charge and hydrophobicity on NP—biomolecule interactions by measuring the composition of adsorbed phospholipids on four NPs, namely, positively charged CeO(2) and ZnO and negatively charged BaS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e36b5420275930c1ecced8ef09ddd31
https://europepmc.org/articles/PMC6507429/
https://europepmc.org/articles/PMC6507429/
Publikováno v:
Colloid and Polymer Science. 293:3319-3324
Self-assembled lipid nanotubes (LNTs) could mimic the lipid bilayer of biological membranes and are widely used as substrates for proteins in the biotechnology. Since the protein-LNT binding depends strongly on the physicochemical properties of the L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fda9c3a0017eee716d4454f1fbe2acd
https://doi.org/10.1007/s00396-015-3688-3
https://doi.org/10.1007/s00396-015-3688-3
Publikováno v:
Thrombosis and Haemostasis. 113:741-749
SummaryNanodiscs (ND) are lipid bilayer membrane patches held by amphiphilic scaffolding proteins (MSP) of ~10 nm in diameter. Nanodiscs have been developed as lipid nanoplatforms for structural and functional studies of membrane and membrane associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcf149b801a09c84bdca90c92394ac0
https://doi.org/10.1160/th14-09-0725
https://doi.org/10.1160/th14-09-0725