Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Svensson Bjorn Eric"'
Publikováno v:
Chemico-Biological Interactions. 94:83-99
( Z )-3-(4-Bromophenyl)-3-(3-pyridyl)allylamine (CPP 200) is transformed to the corresponding chloroimine by hypochlorite ion (ClO − ) formed in the presence of myeloperoxidase. A scheme for this transformation is given. The influence of various co
Publikováno v:
European Journal of Medicinal Chemistry. 30:277-286
Summary In order to further explore the structure—activity relationships of serotonergic 2-aminotetralin derivatives, a total of 12 aryl and heteroaryl substituents have been introduced in the C8-position of 2-(dipropylamino)tetralin. The affinity
Publikováno v:
Free Radical Biology and Medicine. 14:167-175
The abilities of haem peroxidases to catalyse the oxidation of various thiols were studied using the spin-trapping electron spin resonance (ESR) technique. Myeloperoxidase, a neutrophil and monocyte enzyme, catalysed the oxidation of cysteamine, cyst
Autor:
Ye Liu, Svante B. Ross, Lourdes Cortizo, Svensson Bjorn Eric, Tommy Lewander, Hong Yu, Uli Hacksell
Publikováno v:
ChemInform. 24
A series of C8-modified analogues of 8-OH-DPAT (1) have been prepared by facile palladium-catalyzed reactions of the triflates of the enantiomers of 1. Several of the new compounds have high affinity for 5-HT1A-receptors and some are potent agonists.
Autor:
Ye Liu, Hong Yu, Svante B. Ross, Uli Hacksell, Lourdes Cortizo, Tommy Lewander, Svensson Bjorn Eric
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 1:257-262
A series of C8-modified analogues of 8-OH-DPAT (1) have been prepared by facile palladium-catalyzed reactions of the triflates of the enantiomers of 1. Several of the new compounds have high affinity for 5-HT1A-receptors and some are potent agonists.
Autor:
Svensson Bjorn Eric
Publikováno v:
Chemico-Biological Interactions. 70:323-337
Cysteamine and reduced glutathione were shown to act synergistically as peroxidase-oxidase substrates as measured by oxygen consumption and Nitro Blue Tetrazolium reduction. Cysteine methyl ester could be substituted for cysteamine and N-acetylcystei
Autor:
Kajsa Norbeck, David Thompson, Despina Constantin-Teodosiu, Svensson Bjorn Eric, Peter Moldéus
Publikováno v:
Chemical Research in Toxicology. 2:186-192
Eugenol has recently been associated with the toxic effects of clove cigarettes on human lungs. We have studied the metabolism and adverse effects of eugenol on human polymorphonuclear leukocytes (PMNs). Myeloperoxidase, isolated and purified from hu
Autor:
Svensson Bjorn Eric
Publikováno v:
Chemico-biological interactions. 70(3-4)
Myeloperoxidase-oxidase reactions with close to physiological concentrations of thiols and phenols were studied. Cysteine was shown to be a myeloperoxidase-oxidase substrate when catalytic amounts of serotonin were added as cosubstrate. Penicillamine