Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase

Autor: Skytte, DM, Møller, Jesper Vuust, Liu, H, Nielsen, HØ, Svenningsen, LE, Jensen, CM, Olesen, Claus, Christensen, SB

Publikováno v: Skytte, DM, Møller, J V, Liu, H, Nielsen, HØ, Svenningsen, LE, Jensen, CM, Olesen, C & Christensen, SB 2010, ' Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase. ', Bioorganic & Medicinal Chemistry, vol. 18, pp. 5634-5646 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::bd45c5a08463ab8bacf13b4f43b62272
https://pure.au.dk/portal/da/publications/elucidation-of-the-topography-of-the-thapsigargin-binding-site-in-the-sarcoendoplasmic-calcium-atpase(2378b1ab-2dfd-4601-995a-c00088568665).html

Thapsigargin and its prodrug derivatives: exploring novel approaches for targeted cancer therapy through calcium signaling disruption.

Autor: Khurram I; Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.; Centre for Applied Molecular Biology, University of the Punjab, Lahore, Pakistan., Khan MU; Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan. muhammad.umer4@mlt.uol.edu.pk., Ibrahim S; Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.; Centre for Applied Molecular Biology, University of the Punjab, Lahore, Pakistan., Ghani MU; Centre for Applied Molecular Biology, University of the Punjab, Lahore, Pakistan., Amin I; Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan., Falzone L; Department of Biomedical and Biotechnological Sciences, University of Catania, 95123, Catania, Italy., Herrera-Bravo J; Departamento de Ciencias Básicas, Facultad de Ciencias, Universidad Santo Tomas, Santiago, Chile. jesusherrerabr@santotomas.cl., Setzer WN; Aromatic Plant Research Center, 230 N 1200 E, Suite 102, Lehi, UT, 84043, USA.; Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL, 35899, USA., Sharifi-Rad J; Universidad Espíritu Santo, Samborondón, Ecuador. javad.sharifirad@gmail.com.; Centro de Estudios Tecnológicos y, Universitarios del Golfo, Veracruz, Mexico. javad.sharifirad@gmail.com.; Department of Medicine, College of Medicine, Korea University, Seoul, 02841, Republic of Korea. javad.sharifirad@gmail.com., Calina D; Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349, Craiova, Romania. calinadaniela@gmail.com.

Publikováno v: Medical oncology (Northwood, London, England) [Med Oncol] 2024 Nov 19; Vol. 42 (1), pp. 7. Date of Electronic Publication: 2024 Nov 19.

From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development.

Autor: Christensen SB; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen Ø, Denmark. soren.christensen@sund.ku.dk., Simonsen HT; Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Bld 223, 2800, Kgs. Lyngby, Denmark., Engedal N; Department of Tumor Biology, Institute for Cancer Research, University Hospital, Montebello, 0379, Oslo, Norway., Nissen P; Department of Molecular Biology and Genetics, Danish Research Institute of Translational Neuroscience - DANDRITE, Nordic EMBL Partnership for Molecular Medicine, Aarhus University, Gustav Wieds Vej 10C, 8000, Aarhus C, Denmark., Møller JV; Department of Biomedicine, Aarhus University, Ole Worms Allé 3, Bld 1182, Room 114, 8000, Aarhus C, Denmark., Denmeade SR; Department of Oncology, Prostate Cancer Program, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Maryland, The Johns Hopkins University School of Medicine, Baltimore, The Bunting-Blaustein Cancer Research Building, 1650 Orleans Street, Baltimore, MD, 21231, USA., Isaacs JT; Department of Oncology, Prostate Cancer Program, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Maryland, The Johns Hopkins University School of Medicine, Baltimore, The Bunting-Blaustein Cancer Research Building, 1650 Orleans Street, Baltimore, MD, 21231, USA.

Publikováno v: Progress in the chemistry of organic natural products [Prog Chem Org Nat Prod] 2021; Vol. 115, pp. 59-114.