Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Svenja V. Trossbach"'
Autor:
Mohammad Seidisarouei, Sandra Schäble, Marijn van Wingerden, Svenja V. Trossbach, Carsten Korth, Tobias Kalenscher
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Deficits in social interaction or social cognition are key phenotypes in a variety of chronic mental diseases, yet, their modeling and molecular dissection are only in their infancy. The Disrupted-in-Schizophrenia 1 (DISC1) signaling pathway
Externí odkaz:
https://doaj.org/article/59b321a8206a4d1c82ba472db7514020
Autor:
Mohammad Seidisarouei, Sandra Schäble, Marijn vanWingerden, Svenja V. Trossbach, Carsten Korth, Tobias Kalenscher
Publikováno v:
Brain and Behavior, Vol 13, Iss 5, Pp n/a-n/a (2023)
Abstract Patients diagnosed with neuropsychiatric disorders, such as autism and schizophrenia, suffer from disorganized speech. The disrupted‐in‐schizophrenia 1 (DISC1) protein pathway is considered a risk factor for the development of several ps
Externí odkaz:
https://doaj.org/article/f596c037417d44ba8ef35ed868d35cb9
Autor:
Fernando J. Sialana, An-Li Wang, Benedetta Fazari, Martina Kristofova, Roman Smidak, Svenja V. Trossbach, Carsten Korth, Joseph P. Huston, Maria A. de Souza Silva, Gert Lubec
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Disrupted-in-schizophrenia 1 (DISC1) is a key protein involved in behavioral processes and various mental disorders, including schizophrenia and major depression. A transgenic rat overexpressing non-mutant human DISC1, modeling aberrant proteostasis
Externí odkaz:
https://doaj.org/article/c5a986ab4010481a8df67226d7f0f90a
Autor:
An-Li, Wang, Owen Y, Chao, Susanne, Nikolaus, Valeria, Lamounier-Zepter, Cornelis P, Hollenberg, Gert, Lubec, Svenja V, Trossbach, Carsten, Korth, Joseph P, Huston
Publikováno v:
Neuroscience. 493:41-51
Alterations in cognitive functions, social behaviors and stress reactions are commonly diagnosed in chronic mental illnesses (CMI). Animal models expressing mutant genes associated to CMI represent either rare mutations or those contributing only min
Autor:
null Mohammad Seidisarouei, null Sandra Schäble, null Marijn van Wingerden, null Svenja V. Trossbach, null Carsten Korth, null Tobias Kalenscher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f6e73fb98017b959520f19bc52e71d3
https://doi.org/10.1002/brb3.2984/v2/response1
https://doi.org/10.1002/brb3.2984/v2/response1
Publikováno v:
Trends in Neurosciences. 44:352-365
The ability of viruses to evolve several orders of magnitude faster than their host cells has enabled them to exploit host cellular machinery by selectively recruiting multiprotein complexes (MPCs) for their catalyzed assembly and replication. This h
Autor:
Svenja V. Trossbach, Shriya Sahu, Suganya Selvarajah, Andreas Müller-Schiffmann, Ana Raquel Moreira, Vishwanath R. Lingappa, Irina Soloviev, Ingrid Prikulis, Sebastian Hänsch, Carsten Korth, Rita Marreiros, Stefanie Weidtkamp-Peters
Publikováno v:
Proc Natl Acad Sci U S A
Neurodegenerative diseases feature specific misfolded or misassembled proteins associated with neurotoxicity. The precise mechanisms by which protein aggregates first arise in the majority of sporadic cases have remained unclear. Likely, a first crit
Autor:
Karola Kaefer, Joseph O'Neill, Hugo Malagon-Vina, Carsten Korth, Svenja V. Trossbach, Jozsef Csicsvari, Desiree D. Dickerson
Publikováno v:
Hippocampus
Aberrant proteostasis of protein aggregation may lead to behavior disorders including chronic mental illnesses (CMI). Furthermore, the neuronal activity alterations that underlie CMI are not well understood. We recorded the local field potential and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c655df37cf82a26c3e1bfe6101d8c929
Autor:
Svenja V. Trossbach, Claudia Mattern, Carsten Korth, Maria A. de Souza Silva, Joseph P. Huston, An-Li Wang, Fernando J. Sialana, Benedetta Fazari, Susanne Nikolaus, Owen Y. Chao, Gert Lubec
Publikováno v:
Experts@Minnesota
The Disrupted-in-Schizophrenia 1 (DISC1) gene has been associated with mental illnesses such as major depression and schizophrenia. The transgenic DISC1 (tgDISC1) rat, which overexpresses the human DISC1 gene, is known to exhibit deficient dopamine (
Autor:
Charles Curtis, Rick A. Adams, Carsten Korth, Oliver D. Howes, Sang Hyuck Lee, Tarik Dahoun, Svenja V. Trossbach, Hamel Patel, Matthew M. Nour
Publikováno v:
Genes, Brain and Behavior. 18
The disrupted‐in‐schizophrenia 1 (DISC1) protein has been implicated in a range of biological mechanisms underlying chronic mental disorders such as schizophrenia. Schizophrenia is associated with abnormal striatal dopamine signalling, and all an