Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Svenja Thies"'
Autor:
Svenja Thies, Martina Friess, Lukas Frischknecht, Dimitri Korol, Emanuela Felley-Bosco, Rolf Stahel, Bart Vrugt, Walter Weder, Isabelle Opitz, Alex Soltermann
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139312 (2015)
The epithelioid and sarcomatoid histologic variants of malignant pleural mesothelioma (MPM) can be considered as E- and M-parts of the epithelial-mesenchymal transition (EMT) axis; the biphasic being an intermediate. EMT is associated with an increas
Externí odkaz:
https://doaj.org/article/271d55dfb20e4ef3898f281445e4f1c1
Autor:
Emanuela Felley-Bosco, Rolf A. Stahel, Walter Weder, Svenja Thies, Hubert Rehrauer, Alex Soltermann, Isabelle Opitz, Ubiratan Moura, Yandong Shi
Purpose: The aim of this study was to assess the activity of hedgehog signaling pathway in malignant pleural mesothelioma (MPM).Experimental Design: The expression of hedgehog signaling components was assessed by quantitative PCR and in situ hybridiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e08347f82f4ea2d48208e8dcbea02e
https://doi.org/10.1158/1078-0432.c.6522537
https://doi.org/10.1158/1078-0432.c.6522537
Autor:
Emanuela Felley-Bosco, Rolf A. Stahel, Walter Weder, Svenja Thies, Hubert Rehrauer, Alex Soltermann, Isabelle Opitz, Ubiratan Moura, Yandong Shi
PDF file, 96K, 1A. Expression of HH pathway components in non-tumoral pleural tissue and mesothelioma tumors. Quantitative real-time PCR analysis of SMO, GLI2, IHH, DHH gene expression in non-tumoral pleural tissue (NT) and tumor (T). 1B. Overall sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1957dad271e52e22190af0a36395f5c6
https://doi.org/10.1158/1078-0432.22452672
https://doi.org/10.1158/1078-0432.22452672
Autor:
Emanuela Felley-Bosco, Rolf A. Stahel, Walter Weder, Svenja Thies, Hubert Rehrauer, Alex Soltermann, Isabelle Opitz, Ubiratan Moura, Yandong Shi
PDF file, 50K, GLI1 transfection (GLI1) leads to increased expression of GLI1 target HHIP compared to control vector (V) transfected ZL55SPT cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6166835aa32097679949f66858d234f2
https://doi.org/10.1158/1078-0432.22452660.v1
https://doi.org/10.1158/1078-0432.22452660.v1
Autor:
Emanuela Felley-Bosco, Rolf A. Stahel, Walter Weder, Svenja Thies, Hubert Rehrauer, Alex Soltermann, Isabelle Opitz, Ubiratan Moura, Yandong Shi
PDF file, 66K, Western blot analysis of NF2 protein in SDM103T, ZL55SPT cells. SDM71 cells were used as positive control (1). 1. Thurneysen C, Opitz I, Kurtz S, Weder W, Stahel RA, Felley-Bosco E. Functional inactivation of NF2/merlin in human mesoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bea95bba97848a5a4af23f5d121f3af
https://doi.org/10.1158/1078-0432.22452657.v1
https://doi.org/10.1158/1078-0432.22452657.v1
Autor:
Emanuela Felley-Bosco, Rolf A. Stahel, Walter Weder, Svenja Thies, Hubert Rehrauer, Alex Soltermann, Isabelle Opitz, Ubiratan Moura, Yandong Shi
PDF file, 60K, MPM primary cultures maintained without serum in 3% oxygen show a three-fold increase in expression of ABCG2, GLI1 and PATCH1 compared to cultures without serum in 20% oxygen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b985064795ea002a65cd436c976bd96
https://doi.org/10.1158/1078-0432.22452669
https://doi.org/10.1158/1078-0432.22452669
Autor:
Emanuela Felley-Bosco, Rolf A. Stahel, Walter Weder, Svenja Thies, Hubert Rehrauer, Alex Soltermann, Isabelle Opitz, Ubiratan Moura, Yandong Shi
PDF file, 36K, Table S1: Primers used for RT-PCR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014341ac28301bf7ab1e0434a8f47296
https://doi.org/10.1158/1078-0432.22452651
https://doi.org/10.1158/1078-0432.22452651
Autor:
Emanuela Felley-Bosco, Rolf A. Stahel, Walter Weder, Svenja Thies, Hubert Rehrauer, Alex Soltermann, Isabelle Opitz, Ubiratan Moura, Yandong Shi
PDF file, 159K, HHIP protein is expressed in all tumor cells and its levels are increased by HhAntag. Immunohistochemistry analysis of HHIP expression was performed on xenograft tumors of control and HhAntag treated mice. H score was determined based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b81113abe6c3770724179d492b8d0a
https://doi.org/10.1158/1078-0432.22452654
https://doi.org/10.1158/1078-0432.22452654
Autor:
Peter Schraml, Isabel Tritschler, Simon L. Goodman, Ghazaleh Tabatabai, Michaela Weller, Gabriele Maurer, Manuela Silginer, Patrick Roth, Kathy Hasenbach, Svenja Thies, Holger Moch
Transforming growth factor-β is a central mediator of the malignant phenotype of glioblastoma, the most common and malignant form of intrinsic brain tumours. Transforming growth factor-β promotes invasiveness and angiogenesis, maintains cancer cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f319f56903962af11f98560b47653f10
http://doc.rero.ch/record/304868/files/aws351.pdf
http://doc.rero.ch/record/304868/files/aws351.pdf
Autor:
Julia Slotta-Huspenina, Katja Ott, Rupert Langer, Florian Lordick, Evanthia Karamitopoulou, Svenja Thies, Inti Zlobec, Marcus Feith, Karen Becker
Publikováno v:
Karamitopoulou, Evanthia; Thies, Svenja; Zlobec, Inti; Ott, Katja; Feith, Marcus; Slotta-Huspenina, Julia; Lordick, Florian; Becker, Karen; Langer, Rupert (2014). Assessment of tumor regression of esophageal adenocarcinomas after neoadjuvant chemotherapy: comparison of 2 commonly used scoring approaches. The American journal of surgical pathology, 38(11), pp. 1551-1556. Lippincott Williams & Wilkins 10.1097/PAS.0000000000000255
Histopathologic determination of tumor regression provides important prognostic information for locally advanced gastroesophageal carcinomas after neoadjuvant treatment. Regression grading systems mostly refer to the amount of therapy-induced fibrosi