Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Svenja Laue"'
Autor:
Stefanie Sudhop, Harald Lahm, Thomas Brade, Sharon L. Paige, Alexander Goedel, Svenja Laue, Thomas Meitinger, Markus Krane, Stefanie A. Doppler, Alessandra Moretti, Connie R. Bezzina, Pedro Schneider, Zhong Zhang, Makoto Sahara, Neil E. Bowles, Hilansi Rawat, Riccardo Berutti, Nazan Puluca, Ilaria My, Peter J. Gruber, Andreas Dendorfer, Ralf Gilsbach, Nora Lang, M. Dreßen, Christine M. Schneider, S. Schwarz, Daniel Sinnecker, I. Neb, Gianluca Santamaria, Karl-Ludwig Laugwitz, Rüdiger Lange, Sean M. Wu, Bruce D. Gelb, C. Abou-Ajram, Tatjana Dorn, Fleur V.Y. Tjong, Lia Crotti, Maria Rijlaarsdam, Matthias Mann, Christian Kupatt, Lutz Hein, Julie Cleuziou, Elisa Mastantuono, Lesca M. Holdt, Sophia Doll, Bernd H. Northoff
Publikováno v:
Circulation 144, 1409-1428 (2021)
Circulation
bioRxiv
Circulation, 144(17), 1409-1428. Lippincott Williams and Wilkins
Circulation
bioRxiv
Circulation, 144(17), 1409-1428. Lippincott Williams and Wilkins
Supplemental Digital Content is available in the text.
Background: Complex molecular programs in specific cell lineages govern human heart development. Hypoplastic left heart syndrome (HLHS) is the most common and severe manifestation within the
Background: Complex molecular programs in specific cell lineages govern human heart development. Hypoplastic left heart syndrome (HLHS) is the most common and severe manifestation within the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0de69ffa304c5f2a963a861f6f795c
https://doi.org/10.1101/2021.04.24.441110
https://doi.org/10.1101/2021.04.24.441110
Autor:
Kristin Raedecke, Karl-Ludwig Laugwitz, Johannes W.G. Janssen, Sebastian Clauss, Alessandra Moretti, Tatjana Dorn, Gudrun A. Rappold, Anna Jauch, Birgit Campbell, Svenja Laue, Simon Sumer, Sandra Hoffmann, Stefan Kääb, Viktoria Frajs
Publikováno v:
Stem Cell Reports
Summary Patient-specific human induced pluripotent stem cells (hiPSCs) offer unprecedented opportunities for the investigation of multigenic disease, personalized medicine, and stem cell therapy. For heterogeneous diseases such as atrial fibrillation
Autor:
Monika Kustermann, Svenja Laue, Yinghong Cui, Douglas G. Tilley, Laurel A. Grisanti, Melanie Rothe, Michael Kauk, Carsten Hoffmann, Melanie Philipp, WH Zimmermann, Teresa Casar Tena, Allessandra Moretti, Farah Raad, Michael Kühl, Martina S. Burczyk, Sabrina Matysik, Martin D. Burkhalter, Cornelia Donow, Jürgen Wess
Publikováno v:
JCI Insight
Deterioration or inborn malformations of the cardiac conduction system (CCS) interfere with proper impulse propagation in the heart and may lead to sudden cardiac death or heart failure. Patients afflicted with arrhythmia depend on antiarrhythmic med
Autor:
Zuwen Zhang, M. Dreßen, Bernd H. Northoff, Lesca M. Holdt, Ruediger Lange, K L Laugwitz, Markus Krane, I. Neb, Stefanie A. Doppler, Svenja Laue, Daniel Teupser, Harald Lahm, A. Gödel, Alessandra Moretti, Marcus-André Deutsch
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 66:S1-S110
Autor:
M Dressen, Alessandra Moretti, Markus Krane, Ilaria My, F Schmidt, K L Laugwitz, H Lickert, H Lahm, Tatjana Dorn, Svenja Laue, Alexander Goedel, Thomas Brade
Publikováno v:
European Heart Journal. 39
Autor:
Christian Baarlink, Elisabeth Graf, Karl-Ludwig Laugwitz, Tatjana Dorn, Giovanni Cuda, Christian Kupatt, Thomas Meitinger, Elisa Mastantuono, Andrew A. Grace, Dorota M Zawada, Ilaria My, Stefan Kääb, Elvira Immacolata Parrotta, Jessica Kornherr, Austin Smith, Laura Iop, Ralf J. Dirschinger, Gianluca Santamaria, Robert Grosse, Alexander Goedel, Harold Ayetey, Rabea Hinkel, Alessandra Moretti, Daniel Sinnecker, Tarik Bozoglu, Svenja Laue, Tilman Ziegler
Publikováno v:
The EMBO Journal
Cell–cell and cell–matrix interactions guide organ development and homeostasis by controlling lineage specification and maintenance, but the underlying molecular principles are largely unknown. Here, we show that in human developing cardiomyocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f9a5c5b5a3247bc2a7ceb0878281a0
https://www.repository.cam.ac.uk/handle/1810/280257
https://www.repository.cam.ac.uk/handle/1810/280257
Autor:
François Pattou, Gitanjali Dharmadhikari, Julie Kerr-Conte, Svenja Laue, Payal Shah, Desiree M. Schumann, Kathrin Maedler, Thomas Klein, Amin Ardestani
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 98:E1163-E1172
Inhibition of dipeptidyl peptidase-4 (DPP-4) is a potent strategy to increase glucose-dependent insulinotropic polypeptide and glucagon like peptide 1 (GLP-1) induced insulin secretion in diabetes. It is important to know whether new drugs approved f
Autor:
Roland Seifert, Jeroen J. M. W. van den Heuvel, Frans G. M. Russel, Volkhard Kaever, Svenja Laue, Moritz Winterhoff
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology, 387, 9, pp. 893-5
Naunyn-Schmiedeberg's Archives of Pharmacology, 387, 893-5
Naunyn-Schmiedeberg's Archives of Pharmacology, 387, 893-5
Contains fulltext : 137290.pdf (Publisher’s version ) (Closed access) The cyclic pyrimidine nucleotide cCMP has been suggested to serve as second messenger. However, phosphodiesterases studied so far do not hydrolyze cCMP. Therefore, we searched fo
Autor:
Payal Shah, Amin Ardestani, Gitanjali Dharmadhikari, Svenja Laue, Desiree M. Schumann, Julie Kerr-Conte, Francois Pattout, Thomas Klein, Kathrin Maedler
Publikováno v:
JCEM.
Autor:
Fabienne T. Schulthess, Jose Oberholzer, Gitanjali Dharmadhikari, M. Mühle, Kathrin Maedler, Julie Kerr-Conte, Svenja Laue, François Pattou
Publikováno v:
Molecular metabolism. 1(1-2)
Decreased β-cell mass reflects a shift from quiescence/proliferation into apoptosis, it plays a crucial role in the pathophysiology of diabetes. A major attempt to restore β-cell mass and normoglycemia is to improve β-cell survival. Here we show t