Long-Term Fipronil Treatment Induces Hyperactivity in Female Mice

Autor: Laurent Meijer, Pierrïck Auvray, Svenja Koslowski, Marc Blondel, Camille Latapy

Publikováno v: International Journal of Environmental Research and Public Health, Vol 17, Iss 5, p 1579 (2020)
International Journal of Environmental Research and Public Health
Volume 17
Issue 5

Fipronil is an insecticide widely used for veterinary and agricultural purposes. While its insecticidal properties mostly rely on its high affinity antagonistic activity on insect &gamma
aminobutyric acid (GABA) receptors, fipronil and its main

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89429017e9f90732fd0f483ca4d0ae70
https://www.mdpi.com/1660-4601/17/5/1579

Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides

Autor: Patrick C. Fraering, Jeremy Fraering, Emilie Durieu, Spiros D. Garbis, Svenja Koslowski, Josef Pannee, Laurent Meijer, Morgane Cam, Branka Tavčar, Vesna Eraković Haber, Erik Portelius, Frank Karg, Kazuo Yamamoto, Philipp Koch, Vlatka Bencetić Mihaljević, Pierrïck Auvray, Marion Bodin, Henrik Zetterberg, Patrick Gizzi, Bruce D. Hammock, Kaj Blennow, Toshiharu Suzuki, Bogdan Barnych, Hermeto Gerber, Bettina Bohl, Chiori Omori, Saori Hata, Natalia Vasylieva, Antigoni Manousopoulou

Publikováno v: Journal of Alzheimer's disease : JAD, vol 62, iss 4
Journal of Alzheimer's Disease
Volume 62
Issue 4

Generation of amyloid-β peptides (Aβs) by proteolytic cleavage of the amyloid-β protein precursor (AβPP), especially increased production of Aβ(42)/Aβ(43) over Aβ(40), and their aggregation as oligomers and plaques, represent a characteristic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c32271f97fb48054d71da66d94c7a02
https://escholarship.org/uc/item/6357v0ng