Výsledky vyhledávání - "Svenja Groten"

Natural prevalence of resistance-associated variants in hepatitis C virus NS5A in genotype 3a-infected people who inject drugs in Germany

Autor: Svenja Groten, R. Stefan Ross, Holger Siemann, Andreas Walker, Jörg Timm, Norbert Scherbaum

Publikováno v: Journal of Clinical Virology. 70:43-45

Background People who inject drugs (PWID) are the most important risk group for incident Hepatitis C virus (HCV) infection. In PWID in Europe HCV genotype 3a is highly prevalent. Unfortunately, many of the recently developed directly acting antiviral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1310e256a4ef63cfff50056b7d2ac6
https://doi.org/10.1016/j.jcv.2015.07.008

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Distinct Escape Pathway by Hepatitis C Virus Genotype 1a from a Dominant CD8+ T Cell Response by Selection of Altered Epitope Processing

Autor: Thomas Pietschmann, Dominik A. Megger, Todd M. Allen, Stephanie Pfaender, Andreas Walker, Georg M. Lauer, Arthur Y. Kim, Kathrin Skibbe, Joerg Timm, Svenja Groten, Barbara Sitek, Eike Steinmann, Thomas Kuntzen

Antiviral CD8 + T cells are a key component of the adaptive immune response against HCV, but their impact on viral control is influenced by preexisting viral variants in important target epitopes and the development of viral escape mutations. Immunod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac511802c5e0075ce9af144c635fd02
https://hdl.handle.net/10033/601223

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