Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Svende Pfundstein"'
Autor:
Florian Kast, Martin Schwill, Jakob C. Stüber, Svende Pfundstein, Gabriela Nagy-Davidescu, Josep M. Monné Rodríguez, Frauke Seehusen, Christian P. Richter, Annemarie Honegger, Karen Patricia Hartmann, Thomas G. Weber, Felix Kroener, Patrick Ernst, Jacob Piehler, Andreas Plückthun
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
HER2 acts an oncogenic driver in numerous cancers. Here, the authors design an anti-HER2 biparatopic and tetravalent IgG fusion with inhibitory effects in a xenograft model.
Externí odkaz:
https://doaj.org/article/bbc4cba63fcc425a86335df0941f73d7
Autor:
Amalia Ruiz-Serrano, Christina N. Boyle, Josep M. Monné Rodríguez, Julia Günter, Agnieszka E. Jucht, Svende Pfundstein, Andreas M. Bapst, Thomas A. Lutz, Roland H. Wenger, Carsten C. Scholz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1536 (2022)
Dysregulated energy metabolism is a major contributor to a multitude of pathologies, including obesity and diabetes. Understanding the regulation of metabolic homeostasis is of utmost importance for the identification of therapeutic targets for the t
Externí odkaz:
https://doaj.org/article/c316b0ce60bd44718fa2ef25c687347e
Autor:
Roland H. Wenger, Samantha P M Sherman, Julia Günter, Agnieszka E Jucht, Josep M Monné Rodríguez, Carsten A. Wagner, Giovanni Pellegrini, Amalia Ruiz-Serrano, Yulia L Volkova, Pascal Fluechter, Svende Pfundstein, Carsten C. Scholz, Christoph Schneider
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(12)
OTUB1 is one of the most highly expressed deubiquitinases, counter-regulating the two most abundant ubiquitin chain types. OTUB1 expression is linked to the development and progression of lung cancer and idiopathic pulmonary fibrosis in humans. Howev
Autor:
Sophie L. Dahl, Svende Pfundstein, Rico Hunkeler, Xingtong Dong, Thomas Knöpfel, Patrick Spielmann, Carsten C. Scholz, Karen A. Nolan, Roland H. Wenger
Publikováno v:
Acta physiologica (Oxford, England). 234(3)
Fibroblast-like renal erythropoietin (Epo) producing (REP) cells of the corticomedullary border region "sense" a decrease in blood oxygen content following anaemia or hypoxaemia. Burst-like transcription of Epo during tissue hypoxia is transient and
Autor:
Svende Pfundstein, Branko Simic, Giovanni Pellegrini, Giovanni G. Camici, Lucíola S. Barcelos, Margot Crucet, Thomas F. Lüscher, Sokrates Stein, Brigida Gomes de Almeida Schirmer, Simona Stivala, Paul M. Vanhoutte, Francesco Paneni, Goran Vucicevic, Petra Seebeck
Publikováno v:
Atherosclerosis. 304
Background and aims Peripheral arterial disease (PAD) is an important cause of morbidity and mortality with little effective medical treatment currently available. Nitric oxide (NO) is crucially involved in organ perfusion, tissue protection and angi
Autor:
Ana Filipa Gonçalves, Tomas Hejhal, Antonella Catalano, Ian J. Frew, Svende Pfundstein, Laura P Brandt, Joachim Albers, Peter J. Wild
Publikováno v:
Oncotarget
Soft tissue sarcomas are rare mesenchymal tumours accounting for 1% of adult malignancies and are fatal in approximately one third of patients. Two of the most aggressive and lethal forms of soft tissue sarcomas are angiosarcomas and undifferentiated
Autor:
Edith Hummler, Sophie L. Dahl, Silvana Libertini, Andreas M. Bapst, Carsten C. Scholz, Ilaria M.C. Orlando, Svende Pfundstein, Faik Imeri, Roland H. Wenger, Patrick Spielmann, Karen A. Nolan, Lisa Crowther, Willy Kuo, Sara Santambrogio, David Hoogewijs, Anna Keodara, Irene Abreu-Rodríguez, Vartan Kurtcuoglu, Weihong Qi
Publikováno v:
Kidney international. 95(2)
Erythropoietin (Epo) is essential for erythropoiesis and is mainly produced by the fetal liver and the adult kidney following hypoxic stimulation. Epo regulation is commonly studied in hepatoma cell lines, but differences in Epo regulation between ki
Autor:
Adrian Daly, Eric Grouzmann, Christina N. Boyle, Philippe J. Eugster, Erika Tarasco, Petra Seebeck, Alan G. Harris, Svende Pfundstein, Thomas A. Lutz
Somatostatin analogs are widely used to treat conditions associated with hormonal hypersecretion such as acromegaly and metastatic neuroendocrine tumors. First generation somatostatin analogs, such as octreotide and lanreotide, have high affinity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92bdefe29b58cb1e6e473a9823365d13
https://doi.org/10.5167/uzh-140851
https://doi.org/10.5167/uzh-140851
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