Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Svena Verma"'
Autor:
Jedd D Wolchok, Taha Merghoub, Sadna Budhu, Roberta Zappasodi, Svena Verma, Inna Serganova, Lauren Dong, Levi Mark Mangarin, Yacine Marouf, Jonathan F Khan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f5d34c96234c445483351b5b93532dde
Autor:
Taha Merghoub, Sadna Budhu, Roberta Zappasodi, Levi Mangarin, Svena Verma, Inna Serganova, Rachana Maniyar, Ronald Blasberg, Myat Ko
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/702856aef21c4cb583270d02123e1591
Autor:
Yasin Senbabaoglu, Greg Delgoffe, Ping-Chih Ho, Arnab Ghosh, Svena Verma, McLane Watson, Inna Serganova, Ivan Cohen, Masatomo Maeda, Masahiro Shindo, Rachana Maniyar, Mayuresh Mane, Avigdor Leftin, Matthew Lubin, Myat Kyaw Ko, Mohsen Abu-Akeel, Ellen Ackerstaff, Jason Koutcher, Ronald Blasberg
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/b9686a1d31f84b0980888ec7c87b331e
Autor:
Vincent Ho, Nina Bhardwaj, Timothy Chan, Joseph Park, Stephane Pourpe, Arnab Ghosh, Cansu Cimen Bozkus, Svena Verma, William Duke, Max Jan, Matthew Leventhal, Gabriela Hobbs, Trine Alma Knudsen, Vibe Skov, Lasse Kjær, Thomas Stauffer Larsen, Dennis Lund Hansen, R Coleman Lindsley, Hans Hasselbalch, Jacob Grauslund, Mads Andersen, Morten Holmström, Raajit Rampal, Omar Abdel-Wahab, Ann Mullally
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/9222fa08a4014b8e9549bfc479e67a9b
Autor:
Svena Verma, Inna Serganova, Lauren Dong, Sadna Budhu, Levi Mangarin, Roberta Zappasodi, Taha Merghoub, Jedd D. Wolchok
Publikováno v:
Cancer Research. 83:5873-5873
Tumor reliance on glycolysis is a hallmark of cancer and a mechanism of resistance to immunotherapy. This resistance is due to lactate-mediated immune suppression and competition for glucose between T cells and tumor cells within the tumor microenvir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4b511f20a05f37638e5be7377286cf6
https://doi.org/10.1158/1538-7445.am2023-5873
https://doi.org/10.1158/1538-7445.am2023-5873
Autor:
Mathieu Gigoux, Morten O. Holmström, Roberta Zappasodi, Joseph J. Park, Stephane Pourpe, Cansu Cimen Bozkus, Levi M. B. Mangarin, David Redmond, Svena Verma, Sara Schad, Mariam M. George, Divya Venkatesh, Arnab Ghosh, David Hoyos, Zaki Molvi, Baransel Kamaz, Anna E. Marneth, William Duke, Matthew J. Leventhal, Max Jan, Vincent T. Ho, Gabriela S. Hobbs, Trine Alma Knudsen, Vibe Skov, Lasse Kjær, Thomas Stauffer Larsen, Dennis Lund Hansen, R. Coleman Lindsley, Hans Hasselbalch, Jacob H. Grauslund, Thomas L. Lisle, Özcan Met, Patrick Wilkinson, Benjamin Greenbaum, Manuel A. Sepulveda, Timothy Chan, Raajit Rampal, Mads H. Andersen, Omar Abdel-Wahab, Nina Bhardwaj, Jedd D. Wolchok, Ann Mullally, Taha Merghoub
Publikováno v:
Science Translational Medicine. 14
The majority of JAK2V617F-negative myeloproliferative neoplasms (MPNs) have disease-initiating frameshift mutations in calreticulin (CALR), resulting in a common carboxyl-terminal mutant fragment (CALRMUT), representing an attractive source of neoant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5ff55140f482ee33ec173cfebf6e6b
https://doi.org/10.1126/scitranslmed.aba4380
https://doi.org/10.1126/scitranslmed.aba4380
Autor:
Svena Verma, Inna Serganova, Sadna Budhu, Lauren Dong, Myat Ko, Levi Mangarin, Taha Merghoub, Jedd Wolchok, Roberta Zappasodi
Publikováno v:
Cancer Research. 82:3537-3537
Preferential engagement in glycolysis is a hallmark of cancer cells and contributes to the progression and metastasis of many tumor types, including melanoma and triple-negative breast cancer (TNBC). Tumor reliance on glycolysis is emerging as a mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4eaf096b002560c5a7841c16180945f
https://doi.org/10.1158/1538-7445.am2022-3537
https://doi.org/10.1158/1538-7445.am2022-3537
Autor:
Yu Qian, Irene Guijarro, Ana Galan-Cobo, Minghao Dang, Alissa Poteete, Fahao Zhang, Qi Wang, Jing Wang, Edwin Parra, Ferdinandos Skoulidis, Ignacio Wistuba, Svena Verma, Taha Merghoub, Linghua Wang, Jedd Wolchok, Alexandre Reuben, John Heymach
Publikováno v:
Cancer Research. 82:2160-2160
Genomic alterations that result in loss of function of the tumor suppressor serine/threonine kinase STK11/LKB1 occur in 20-30% of lung adenocarcinomas. We previously observed that STK11/LKB1 mutations are genomic drivers of primary resistance in lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80a609d4335371c2a34f1bfeefa5368b
https://doi.org/10.1158/1538-7445.am2022-2160
https://doi.org/10.1158/1538-7445.am2022-2160
Autor:
Lauren Dong, Hyejin Choi, Sadna Budhu, Isabell Schulze, Svena Verma, Nezar Mehanna, Neal Rosen, Taha Merghoub, Jedd Wolchok
Publikováno v:
Cancer Research. 82:4175-4175
To enhance the therapeutic scope of MEK inhibitors (MEKis), we aim to develop new strategies to extend their usage to MEKi resistant RAS mutant cancers, which represent an unmet clinical need. CH5126766 (CKI27) binds the allosteric site of MEK to inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a59c3f7455bd1b8f480eb7676a3d4d6
https://doi.org/10.1158/1538-7445.am2022-4175
https://doi.org/10.1158/1538-7445.am2022-4175
Autor:
Yu Qian, Ana Galan-Cobo, Irene Guijarro, Minghao Dang, Alissa Poteete, Fahao Zhang, Qi Wang, Jing Wang, Edwin Roger Parra, Ferdinandos Skoulidis, Ignacio Wistuba, Svena Verma, Taha Merghoub, Jedd D. Wolchok, Kwok-Kin Wong, Ralph J. DeBerardinis, John Minna, Linghua Wang, Alexandre Reuben, John Heymach
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8024f88a848f6fb35eee584e0b759984
https://doi.org/10.2139/ssrn.4226205
https://doi.org/10.2139/ssrn.4226205