Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Sven Stegemann"'
Autor:
Li Ding, Ashlee D. Brunaugh, Sven Stegemann, Scott V. Jermain, Matthew J. Herpin, Justin Kalafat, Hugh D. C. Smyth
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1213 (2021)
Capsule-based dry powder inhalers (cDPIs) are widely utilized in the delivery of pharmaceutical powders to the lungs. In these systems, the fundamental nature of the interactions between the drug/formulation powder, the capsules, the inhaler device,
Externí odkaz:
https://doaj.org/article/f96b50400fd64ad794997089c4e78a70
Autor:
Nélio Drumond, Sven Stegemann
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1241 (2020)
Oral drug therapy is generally provided in the form of solid oral dosage forms (SODF) that have to be swallowed and move throughout the oro-esophageal system. Previous studies have provided evidence that the oro-esophageal transit of SODF depends on
Externí odkaz:
https://doaj.org/article/c667dd98125f40fdada972ac8ab243e9
Autor:
Nélio Drumond, Sven Stegemann
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 32 (2020)
Oral drug administration provided as solid oral dosage forms (SODF) remains the major route of drug therapy in primary and secondary care. There is clear evidence for a growing number of clinically relevant swallowing issues (e.g., dysphagia) in the
Externí odkaz:
https://doaj.org/article/a38218b53909480b98eeb9b21d5091c4
Publikováno v:
Pharmaceutics, Vol 11, Iss 4, p 172 (2019)
A meeting organised by the Academy of Pharmaceutical Sciences focussed on the challenges of developing medicines for older adults. International experts discussed the complexity introduced by polypharmacy and multiple morbidities and how the risk–b
Externí odkaz:
https://doaj.org/article/5f37433b321c4fc7838cf28da543dbcb
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 185:1-4
Autor:
Diana A. Riet‐Nales, Bart Bemt, David Bodegom, Francesca Cerreta, Brian Dooley, Doris Eggenschwyler, Blanka Hirschlérova, Paul A. F. Jansen, Fatma Karapinar‐Çarkit, Abigail Moran, Jan Span, Sven Stegemann, Katarina Sundberg
Publikováno v:
British Journal of Clinical Pharmacology, 88, 1500-1514
British Journal of Clinical Pharmacology, 88, 4, pp. 1500-1514
British Journal of Clinical Pharmacology, 88, 4, pp. 1500-1514
Item does not contain fulltext Older people are often affected by impaired organ and bodily functions resulting in multimorbidity and polypharmacy, turning them into the main user group of many medicines. Very often, medicines have not specifically b
Autor:
Sven, Stegemann
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
Autor:
Sven Stegemann, Liz Sheehan, Alessandra Rossi, Andrew Barrett, Amrit Paudel, Abina Crean, Fabrice Ruiz, Massimo Bresciani, Fang Liu, Zakia Shariff, Margarete Shine, Christel Schmelzer, Anne-Marie Pense-Lheritier
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 177
The increasing awareness of acceptability and usability of pharmaceutical drug products by the patient as a key quality requirement continues to drive need for integrating patient centric drug product design into the pharmaceutical development proces
Publikováno v:
Drug discovery today. 28(2)
In 1997, the 'Rule of Five' (Ro5) suggested physicochemical limitations for orally administered drugs, based on the analysis of chemical libraries from the early 1990s. In this review, we report on the trends in oral drug product development by analy