Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sven Stadlbauer"'
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-24 (2024)
Abstract Background Programmed cell death ligand 1 (PD-L1) plays a critical role in the tumor microenvironment and overexpression in several solid cancers has been reported. This was associated with a downregulation of the local immune response, spec
Externí odkaz:
https://doaj.org/article/6b92fb27767c475693a3d55f22417df7
Autor:
Austin Craig, Jürgen Kogler, Markus Laube, Martin Ullrich, Cornelius K. Donat, Robert Wodtke, Klaus Kopka, Sven Stadlbauer
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2749 (2023)
Early detection and treatment of cancers can significantly increase patient prognosis and enhance the quality of life of affected patients. The emerging significance of the tumor microenvironment (TME) as a new frontier for cancer diagnosis and thera
Externí odkaz:
https://doaj.org/article/664a01d0f78c4972ad7e20ef2c2023c5
Autor:
Austin Craig, Jürgen Kogler, Fabian Krutzek, Florian Brandt, Markus Laube, Martin Ullrich, Cornelius Kurt Donat, Klaus Kopka, Sven Stadlbauer
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 127 (2022)
Efficient 18F-fluorination procedures for the production of radiopharmaceuticals are urgently needed to satisfy the increasing demand for clinical diagnostics using positron emission tomography (PET). However, the development of PET tracers is often
Externí odkaz:
https://doaj.org/article/54384e0141a64f7d968e1a127df00aef
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 747 (2022)
Immune checkpoint inhibitor (ICI) therapy has emerged as a major treatment option for a variety of cancers. Among the immune checkpoints addressed, the programmed death receptor 1 (PD-1) and its ligand PD-L1 are the key targets for an ICI. PD-L1 has
Externí odkaz:
https://doaj.org/article/ec4a625cdf6d40b7901dd0c9282fd9e4
Autor:
Thines Kanagasundaram, Markus Laube, Johanna Wodtke, Carsten Sven Kramer, Sven Stadlbauer, Jens Pietzsch, Klaus Kopka
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1155 (2021)
Radiolabeled fluorescent dyes are decisive for bimodal imaging as well as highly in demand for nuclear- and optical imaging. Silicon-rhodamines (SiRs) show unique near-infrared (NIR) optical properties, large quantum yields and extinction coefficient
Externí odkaz:
https://doaj.org/article/465bfa818146467fa886498a4b4866cc
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134336 (2015)
Natural polyphenols like oligomeric catechins (procyanidins) derived from green tea and herbal medicines are interesting compounds for pharmaceutical research due to their ability to protect against carcinogenesis in animal models. It is nevertheless
Externí odkaz:
https://doaj.org/article/2bb5170d129e46ecbdb5a240af34e6fe
Autor:
Fabian Krutzek, Cornelius K. Donat, Martin Ullrich, Kristof Zarschler, Marie-Charlotte Ludik, Anja Feldmann, Liliana R. Loureiro, Klaus Kopka, Sven Stadlbauer
Publikováno v:
Cancers; Volume 15; Issue 9; Pages: 2638
Cancers 15(2023), 2638
Cancers 15(2023), 2638
Noninvasive molecular imaging of the PD-1/PD-L1 immune checkpoint is of high clinical relevance for patient stratification and therapy monitoring in cancer patients. Here we report nine small-molecule PD-L1 radiotracers with solubilizing sulfonic aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46211b5531942ab4d43bf4598ab05790
Autor:
Fabian Krutzek, Cornelius Donat, Martin Ullrich, Liliana Rodrigues Loureiro, Klaus Kopka, Sven Stadlbauer
Publikováno v:
International Symposium on Radiopharmaceutical Sciences, 29.05.-02.06.2022, Nantes, France
Objective: The programmed cell death-ligand 1 (PD-L1) is upregulated on many different cancers and allows the tumor cells to evade immune response through binding to the PD-1 receptor.[1] Monoclonal antibodies, i.e. checkpoint inhibitors, are able to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d93a8d8e6f31e7d08194672db5a4b28
https://www.hzdr.de/publications/Publ-35962-1
https://www.hzdr.de/publications/Publ-35962-1
Autor:
Thines Kanagasundaram, Markus Laube, Robert Wodtke, Sven Stadlbauer, Jens Pietzsch, Klaus Kopka
Publikováno v:
Nuclear Medicine and Biology. :S168-S169
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86be88d2227b6487c0c53fe7655c4a10
https://doi.org/10.1016/s0969-8051(22)00354-7
https://doi.org/10.1016/s0969-8051(22)00354-7
Publikováno v:
Nuclear Medicine and Biology. :S80-S81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::459c39a892acd70a6b6b3174384ab509
https://doi.org/10.1016/s0969-8051(22)00193-7
https://doi.org/10.1016/s0969-8051(22)00193-7