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pro vyhledávání: '"Sven Seelow"'
Autor:
Jijing Wang, Susanna L. Lundström, Sven Seelow, Sergey Rodin, Zhaowei Meng, Juan Astorga-Wells, Qinyu Jia, Roman A. Zubarev
Publikováno v:
Molecules, Vol 26, Iss 21, p 6709 (2021)
Isoaspartate (isoAsp) is a damaging amino acid residue formed in proteins mostly as a result of spontaneous deamidation of asparaginyl residues. An association has been found between isoAsp in human serum albumin (HSA) and Alzheimer’s disease (AD).
Externí odkaz:
https://doaj.org/article/406db28c57ae42aa81e660866e97c59f
Autor:
Jijing Wang, Cong Guo, Zhaowei Meng, Marissa D. Zwan, Xin Chen, Sven Seelow, Susanna L. Lundström, Sergey Rodin, Charlotte E. Teunissen, Roman A. Zubarev
Publikováno v:
Wang, J, Guo, C, Meng, Z, Zwan, M D, Chen, X, Seelow, S, Lundström, S L, Rodin, S, Teunissen, C E & Zubarev, R A 2022, ' Testing the link between isoaspartate and Alzheimer's disease etiology ', Alzheimer's and Dementia . https://doi.org/10.1002/alz.12735
Alzheimer's and Dementia. Elsevier
Alzheimer's and Dementia. Elsevier
Isoaspartate (isoAsp) is a damaging amino acid residue formed in proteins as a result of spontaneous deamidation. IsoAsp disrupts protein structures, making them prone to aggregation. Here we strengthened the link between isoAsp and Alzheimer's disea