Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sven Schönecker"'
Publikováno v:
Diabetes. 68
Increase of blood glucose concentration leads to glucose-induced electrical activity of pancreatic beta-cells followed by insulin secretion. Electrical activity appears in glucose concentration-dependent oscillations easily recorded by microelectrode
Autor:
Elke Guenther, Uwe Lendeckel, Gisela Drews, Martina Düfer, Sven Schönecker, Carmen Härdtner, Winfried Barthlen, Peter Krippeit-Drews, Reinhard Walther, Anika Sahr, Udo Kraushaar
Publikováno v:
Integr. Biol.. 6:540-544
Extracellular recording of the glucose-induced electrical activity of mouse islets of Langerhans on microelectrode arrays (MEAs) is an innovative and powerful tool to address beta-cell (patho-)physiology. In a dual approach we tested whether this tec
Autor:
Sven Schönecker, Udo Kraushaar, D. Haspel, Elke Günther, Gisela Drews, Peter Krippeit-Drews, Martina Düfer, Thomas Pfeiffer
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 462:835-840
The membrane potential (V (m)) of beta-cells oscillates at glucose concentrations between ~6 and 25 mM, i.e. burst phases with action potentials alternate with silent interburst phases generating so-called slow waves. The slow waves drive oscillation
Publikováno v:
Diabetologie und Stoffwechsel. 10
Autor:
Udo Kraushaar, Elke Guenther, Felicia Gerst, Winfried Barthlen, Gisela Drews, Alfred Königsrainer, Sven Schönecker, Susanne Ullrich, Peter Krippeit-Drews, HU Häring
Publikováno v:
Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 123(5)
This study demonstrates for the first time that the microelectrode array (MEA) technique allows analysis of electrical activity of islets isolated from human biopsies. We have shown before that this method, i. e., measuring beta cell electrical activ
Autor:
Peter Krippeit-Drews, A Edalat, Martina Düfer, Gisela Drews, E Guenther, U Kraushaar, Sven Schönecker, B Winter
Publikováno v:
Diabetologie und Stoffwechsel. 7