Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sven P. Fritz"'
Publikováno v:
Angewandte Chemie (International ed. in English)
Oxindoles with adjacent tetrasubstituted stereocenters were obtained in high yields and stereoselectivities by organocatalyzed conjugate addition reactions of monothiomalonates (MTMs) to isatin-derived N-Cbz ketimines. The method requires only a low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797461626de8fa6f00e61620135ec42d
https://doi.org/10.1002/ange.201502976
https://doi.org/10.1002/ange.201502976
Publikováno v:
The Journal of organic chemistry
A method for the stereoselective synthesis of acyclic thioesters bearing adjacent quaternary and tertiary stereogenic centers under mild organocatalytic conditions was developed. α-Substituted monothiomalonates (MTMs) were used as thioester enolate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a59a30085c09134ba77e258efe4ebe2
https://doi.org/10.1021/jo500403q
https://doi.org/10.1021/jo500403q
Publikováno v:
Angewandte Chemie. 126:8924-8928
β-Aminothioester sind wichtige Bausteine fur die Synthese bioaktiver Molekule. Hier wurden organokatalytische Mannich-Reaktionen entwickelt, die direkten und stereoselektiven Zugang zu β2- und β2,3,3-Aminothioestern ausgehend von simplen Bausteine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f9924ead975ba891357cbdcc278c7a9
https://doi.org/10.1002/ange.201310532
https://doi.org/10.1002/ange.201310532
Publikováno v:
Organic Letters. 14:6370-6373
CF(3)-substituted vinyl diphenylsulfonium triflate is an effective annulation reagent for the formation of α-CF(3) substituted, epoxide-fused heterocycles (pyrrolidines, piperidines, and tetrahydrofurans). This simple method affords a variety of val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5624c3901db3bb585081c4fe29c757
https://doi.org/10.1021/ol303200n
https://doi.org/10.1021/ol303200n
Publikováno v:
Helvetica Chimica Acta. 95:2384-2398
A versatile and simple method is reported for the synthesis of bicyclic epoxide and aziridinefused heterocycles (up to 98% yield, up to 96 : 4 er or up to 15 : 1 dr), using a tandem Michael addition/JohnsonCoreyChaykovsky annulation approach. A new c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aee8ea042019e7f1dee54ac18b584d9f
https://doi.org/10.1002/hlca.201200455
https://doi.org/10.1002/hlca.201200455
Publikováno v:
Synthesis. 44:1584-1590
Easily accessible arylglycine derivatives were cyclized to azetidines by using commercially available (2-bromoethyl)sulfonium triflate in a simple and mild procedure. The high-yielding reaction has a relatively broad scope and was extended to the syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27d135d87b28450c09f30f741dacebbd
https://doi.org/10.1055/s-0031-1290951
https://doi.org/10.1055/s-0031-1290951
Publikováno v:
European Journal of Organic Chemistry. 2012:160-166
The effect of the nature of the N-protecting group on 1,2-amino alcohols in annulation reactions with diphenylvinylsulfonium triflate has been investigated. Although tosyl and sulfinamide groups give morpholines in high yields, the use of N-Cbz leads
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2230fd82962d728eba2d154fe47cca22
https://doi.org/10.1002/ejoc.201101272
https://doi.org/10.1002/ejoc.201101272
Publikováno v:
European Journal of Organic Chemistry. 2011:3156-3164
1,2-Amino alcohols have been converted into morpholines by using sulfinamides as temporary protecting/activating groups on the amine. We have developed a procedure for the selective synthesis of monoprotected N-sulfinyl amino alcohols through a doubl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0539ee4b7fb816f3db3435bd61a97d5e
https://doi.org/10.1002/ejoc.201100337
https://doi.org/10.1002/ejoc.201100337
Publikováno v:
ChemInform. 46
Both enantiomers of oxindoles with adjacent tetrasubstituted cyclic and acyclic stereogenic centers can be obtained with excellent stereoselectivities by using either a cinchona alkaloid derivative (EDC) as catalyst or Takemoto′s catalyst in conjug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af5cdb1d6e7eb037298a83c9c781bf9e
https://doi.org/10.1002/chin.201538131
https://doi.org/10.1002/chin.201538131
Autor:
Eoghan M. McGarrigle, Johnathan V. Matlock, Diane Mary Coe, Varinder K. Aggarwal, Stephen A. Harrison, Sven P. Fritz
Publikováno v:
ChemInform. 46
The discovery of new methods for the synthesis of classes of potentially bioactive molecules remains an important goal for synthetic chemists. Vinylsulfonium salts have been used for the synthesis of a wide variety of small heterocyclic motifs; howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76b9af86a64e9199fdf18d7349a1be7d
https://doi.org/10.1002/chin.201516172
https://doi.org/10.1002/chin.201516172