Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sven O. Friedrich"'
Autor:
Edith E. Machowski, Matebogo Letutu, Limakatso Lebina, Ziyaad Waja, Reginah Msandiwa, Minja Milovanovic, Bhavna G. Gordhan, Kennedy Otwombe, Sven O. Friedrich, Richard Chaisson, Andreas H. Diacon, Bavesh Kana, Neil Martinson
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background Pulmonary tuberculosis (TB) in people living with HIV (PLH) frequently presents as sputum smear-negative. However, clinical trials of TB in adults often use smear-positive individuals to ensure measurable bacterial responses follo
Externí odkaz:
https://doaj.org/article/879276020bf045e9ade5f10bfaa38a9d
Autor:
Lauren Philips, Madeleine Lourens, Lize van der Merwe, Amour Venter, Andreas H. Diacon, Sven O. Friedrich, Neil A. Martinson, Carmen C. Kleinhans
Publikováno v:
Tuberculosis. 116:17-21
Mycobacterial sputum culture is a key diagnostic and research tool.To compare mycobacterial culture outcomes of three sputum collection methods.We compared culture results within sets of three sputum samples collected from 18 HIV-infected adult tuber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ac26703a65df27cb60dd0145ab025a
https://doi.org/10.1016/j.tube.2019.03.008
https://doi.org/10.1016/j.tube.2019.03.008
Publikováno v:
Tuberculosis, 115, 140-145
Tuberculosis, 115, pp. 140-145
Tuberculosis, 115, pp. 140-145
Objective Artificial sputum spiked with Mycobacterium tuberculosis could serve for validation of procedures that determine viable mycobacterial load. Design Artificial sputum specimens prepared in-house were spiked with low, medium or high concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53776238aef468f25f6276be581b958
https://hdl.handle.net/2066/202600
https://hdl.handle.net/2066/202600
Autor:
Robert S Wallis, Rodney Dawson, Sven O Friedrich, Amour Venter, Darcy Paige, Tong Zhu, Annette Silvia, Jason Gobey, Craig Ellery, Yao Zhang, Kathleen Eisenach, Paul Miller, Andreas H Diacon
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94462 (2014)
Sutezolid (PNU-100480) is a linezolid analog with superior bactericidal activity against Mycobacterium tuberculosis in the hollow fiber, whole blood and mouse models. Like linezolid, it is unaffected by mutations conferring resistance to standard TB
Externí odkaz:
https://doaj.org/article/1d2f4c6c83044d40877fbbf4225b55e9
Diagnostic utility of bronchoalveolar lavage in children with complicated intrathoracic tuberculosis
Autor:
Roland Croucamp, Megan Palmer, Pierre Goussard, Elisabetta Walters, Anne-Marie Demers, Corné Bosch, Sven O. Friedrich, Lunga Mfingwana, Savvas Andronikou, Jacques T. Janson, Elisa López-Varela, Julie Morrison, Marieke M. van der Zalm, Andrew Whitelaw, Anneke C. Hesseling
Publikováno v:
Pediatric pulmonologyREFERENCES. 56(7)
Introduction Bronchoscopy can be a useful tool in children with pulmonary tuberculosis (PTB) with severe disease potentially requiring intervention or in the face of diagnostic dilemmas. The aim of this study was to determine the value of Xpert MTB/R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ba7df1aa7f2edc996e34001777b1d6
https://pubmed.ncbi.nlm.nih.gov/33818927
https://pubmed.ncbi.nlm.nih.gov/33818927
Publikováno v:
Tuberculosis. 116:32-34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a386651b4d74e5a4e3d44c72b7849557
https://doi.org/10.1016/j.tube.2019.04.001
https://doi.org/10.1016/j.tube.2019.04.001
Publikováno v:
Journal of applied microbiologyReferences. 128(5)
Introduction This study explores the uses of microcalorimetry to detect Mycobacterium tuberculosis (TB) in sputum. Microcalorimetry measures metabolic heat evolution during cellular proliferation of tuberculosis (TB) and is considered as a possible a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e8275dd003ab4042d0930d1e79e81c
https://pubmed.ncbi.nlm.nih.gov/31834654
https://pubmed.ncbi.nlm.nih.gov/31834654
Autor:
Megan Palmer, Anne-Marie Demers, Andrew Whitelaw, Sven O. Friedrich, Heather Draper, Pierre Goussard, Corné Bosch, Robert P. Gie, H S Schaaf, Marieke M. van der Zalm, Elisabetta Walters, Robin M. Warren, Anneke C. Hesseling
Tuberculosis (TB) continues to result in high morbidity and mortality in children from resource-limited settings. Diagnostic challenges, including resource-intense sputum collection methods and insensitive diagnostic tests, contribute to diagnostic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be39b5cc2e47ae55d109c5b3ee4adb60
https://europepmc.org/articles/PMC5558052/
https://europepmc.org/articles/PMC5558052/
Mycobacterium tuberculosis strains with spontaneous mutations conferring resistance to rifampin (RIF) are exceedingly rare, and fixed drug combinations typically prevent augmentation of resistance to single drugs. Fourteen newly diagnosed tuberculosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77459e63bbf7917bb997bed3af990a1
https://europepmc.org/articles/PMC5365665/
https://europepmc.org/articles/PMC5365665/
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:3306-3311
Sutezolid (PNU-100480 [U-480]) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis. An active sulfoxide metabolite (PNU-101603 [U-603]), which reaches concentrations in plasma several times those of the parent, has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc4501080a4af86cc49ecbb0ac1de6c
https://doi.org/10.1128/aac.01920-13
https://doi.org/10.1128/aac.01920-13