Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Sven Löffeler"'
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Akademický článek
No significant difference in intermediate key outcomes in men with low- and intermediate-risk prostate cancer managed by active surveillance
Autor: Karolina Cyll, Sven Löffeler, Birgitte Carlsen, Karin Skogstad, May Lisbeth Plathan, Martin Landquist, Erik Skaaheim Haug
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Active surveillance (AS) is standard of care for patients with low-risk prostate cancer (PCa), but its feasibility in intermediate-risk patients is controversial. We compared outcomes of low- and intermediate-risk patients managed with multi
Externí odkaz: https://doaj.org/article/86dbf7325f9f4ceea8b17e6ded8d38a0
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2
Akademický článek
Randomised double-blind phase 3 clinical study testing impact of atorvastatin on prostate cancer progression after initiation of androgen deprivation therapy: study protocol
Autor: Terho Lehtimäki, Antti Rannikko, Mikkel Fode, Michael Borre, Teuvo Tammela, Aino Siltari, Peter Østergren, Mika Helminen, Timo Marttila, Otto Ettala, Heikki Seikkula, Peter Boström, Jarno Riikonen, Juha Koskimäki, Tomi Pakarainen, Andres Kotsar, Paavo V Raittinen, Arto Salonen, Hanna Ronkainen, Sven Löffeler, Teemu J Murtola
Publikováno v: BMJ Open, Vol 12, Iss 4 (2022)
Introduction Blood cholesterol is likely a risk factor for prostate cancer prognosis and use of statins is associated with lowered risk of prostate cancer recurrence and progression. Furthermore, use of statins has been associated with prolonged time
Externí odkaz: https://doaj.org/article/e505fd6f8e7d4cd2a0760857e0947b59
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4
Randomised double-blind phase 3 clinical study testing impact of atorvastatin on prostate cancer progression after initiation of androgen deprivation therapy : study protocol
Autor: Aino Siltari, Jarno Riikonen, Juha Koskimäki, Tomi Pakarainen, Otto Ettala, Peter Boström, Heikki Seikkula, Andres Kotsar, Teuvo Tammela, Mika Helminen, Paavo V Raittinen, Terho Lehtimäki, Mikkel Fode, Peter Østergren, Michael Borre, Antti Rannikko, Timo Marttila, Arto Salonen, Hanna Ronkainen, Sven Löffeler, Teemu J Murtola
Publikováno v: Siltari, A, Riikonen, J, Koskimäki, J, Pakarainen, T, Ettala, O, Boström, P, Seikkula, H, Kotsar, A, Tammela, T, Helminen, M, Raittinen, P V, Lehtimäki, T, Fode, M, Østergren, P, Borre, M, Rannikko, A, Marttila, T, Salonen, A, Ronkainen, H, Löffeler, S & Murtola, T J 2022, ' Randomised double-blind phase 3 clinical study testing impact of atorvastatin on prostate cancer progression after initiation of androgen deprivation therapy : study protocol ', BMJ Open, vol. 12, no. 4, e050264 . https://doi.org/10.1136/bmjopen-2021-050264
IntroductionBlood cholesterol is likely a risk factor for prostate cancer prognosis and use of statins is associated with lowered risk of prostate cancer recurrence and progression. Furthermore, use of statins has been associated with prolonged time
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4944b012a4cd842994136075a1e269c
http://hdl.handle.net/10138/344338
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5
Biomarker discrimination and calibration with MRI-targeted biopsies: an analysis with the Stockholm3 test
Autor: Henrik Grönberg, Sven Löffeler, Martin Eklund, Erik Skaaheim Haug, Wolfgang Picker, Tobias Nordström, Thorgerdur Palsdottir, Hari T. Vigneswaran, Henrik Olsson
Publikováno v: Prostate Cancer and Prostatic Diseases. 24:457-464
Background The validated Stockholm3 test is used to improve PC detection. Stockholm3, however, was developed using systematic biopsies. We aimed to assess Stockholm3 operating performance when using MRI-targeted biopsies for PC detection. Methods A p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b0f0c0c35681c6156c284037c286cd
https://doi.org/10.1038/s41391-020-00297-x
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6
Non-metastatic prostate cancer: rationale for conservative treatment and impact on disease-related morbidity and mortality in the elderly
Autor: Haris Fawad, Erik Skaaheim Haug, Christian Beisland, Adrian Halland, Sven Löffeler
Publikováno v: Scandinavian Journal of Urology
Purpose: To determine the rationale for not offering local treatment to prostate cancer patients with non-metastatic disease at diagnosis who later died of prostate cancer and to document local and systemic complications caused by disease progression
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c784236da17e42507ad2b6ed10daaa72
https://pubmed.ncbi.nlm.nih.gov/32133899
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7
Tumour heterogeneity poses a significant challenge to cancer biomarker research
Autor: Elin Ersvær, Ljiljana Vlatkovic, Marte Avranden Kjær, Tarjei S. Hveem, Håvard E. Danielsen, Erik Skaaheim Haug, Andreas Kleppe, Birgitte Carlsen, Silje Gill, Sven Löffeler, Wanja Kildal, Karolina Cyll, Manohar Pradhan, Håkon Wæhre, Prasanna Sooriakumaran
Publikováno v: British Journal of Cancer
Background: The high degree of genomic diversity in cancer represents a challenge for identifying objective prognostic markers. We aimed to examine the extent of tumour heterogeneity and its effect on the evaluation of a selected prognostic marker us
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930d9742104ae4920479445a432eea01
https://doi.org/10.1038/bjc.2017.171
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8
High Norwegian prostate cancer mortality: evidence of over-reporting
Autor: Adrian Halland, Anastasia Nikitenko, Erik Skaaheim Haug, Harald Weedon-Fekjær, Sven Löffeler, Christian Lycke Ellingsen
Publikováno v: Scandinavian journal of urology
Objective: This study aimed to determine the level of misattribution of prostate cancer deaths in Norway based on the county of Vestfold in the years 2009–2014. Materials and methods: The study included 328 patients registered as dead from prostate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44251024cdecdc15c2ccd6285258588a
http://hdl.handle.net/11250/2585524
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9
'Natural course' of disease in patients with metastatic castrate-resistant prostate cancer: Survival and prognostic factors without life-prolonging treatment
Autor: Marte Sofie Wang-Hansen, Sophie D. Fosså, Hanne Hamre, Erik Skaaheim Haug, Sven Löffeler, Harald Weedon-Fekjær, Karin S. Sebakk
Publikováno v: Scandinavian journal of urology. 49(6)
The aim of this study was to determine survival and prognostic factors in unselected patients with metastatic castrate-resistant prostate cancer (mCRPC), who never received life-prolonging treatment.The study was a retrospective analysis of a consecu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15686239d7d0aa3ce3edcc7feb9bcd17
https://pubmed.ncbi.nlm.nih.gov/26139461
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10
Donor-derived alloantigen-presenting cells persist in the liver allograft during tolerance induction
Autor: Sven Löffeler, Christoph Otto, Karin Ulrichs, Arnulf Thiede, Wolfgang Timmermann, S. Czub, Detlef Meyer, Heinz-Jochen Gassel
Publikováno v: Transplant international : official journal of the European Society for Organ Transplantation. 13(1)
The predictive value of chimerism was evaluated in three different transplantation models in the rat without immunosuppression: small bowel- (SBTx), liver- (LTx), and liver/small bowel transplantation (LSBTx) were performed in the Brown Norway (BN)-t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3248358e31ab73ecd6aef93ae47879
https://pubmed.ncbi.nlm.nih.gov/10743684
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