Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sven Kochmann"'
Publikováno v:
Analytical Chemistry. 95:3563-3568
Publikováno v:
Analytical Chemistry. 94:9519-9524
Molecular stream separation (MSS) is a promising complement for continuous-flow synthesis. MSS is driven by forces exerted on molecules by a field applied at an angle to the stream-carrying flow. MSS has only been performed with a 90° field-to-flow
The determination of accurate equilibrium dissociation constants Kd of protein–small molecule complexes is important but challenging as all established methods have inherent sources of inaccuracy. ACTIS is a new method for Kd determination using tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::266dfa636901c42dd30c596950544fe5
https://doi.org/10.26434/chemrxiv-2022-ct450
https://doi.org/10.26434/chemrxiv-2022-ct450
Autor:
Sergey N. Krylov, Tong Ye Wang, Sven Kochmann, Nikita A Ivanov, Boris I. Gorin, J. C. Yves Le Blanc, Jean-Luc Rukundo
Publikováno v:
Analytical Chemistry. 93:11654-11659
Accurate Constant via Transient Incomplete Separation (ACTIS) is a new method for finding the equilibrium dissociation constant Kd of a protein-small molecule complex based on transient incomplete separation of the complex from the unbound small mole
Publikováno v:
Analytical Chemistry. 93:9980-9985
In molecular-stream separation (MSS), a stream of a multi-component mixture is separated into multiple streams of individual components. Quantitative evaluation of MSS data has been a bottleneck in MSS for decades as there was no conventional way to
Autor:
Jean-Luc Rukundo, Sven Kochmann, Tong Ye Wang, Nikita A. Ivanov, J.C. Yves Le Blanc, Boris I. Gorin, Sergey N. Krylov
ACTIS is a new method for finding the equilibrium dissociation constant Kd of a protein–small molecule complex based on transient incomplete separation of the complex from the unbound small molecule in a capillary. This separation is caused by diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c23d9e56480e7a50aefe5a3fec0c146
https://doi.org/10.26434/chemrxiv.14574315
https://doi.org/10.26434/chemrxiv.14574315
Cytometry of reaction rate constant (CRRC) is an accurate and robust approach to characterize cell-population heterogeneity using rate constants of cellular processes for which kinetic mechanisms are known. We work on a CRRC-based method to develop p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1102f7315f5ebbea154860218b8bb86f
https://doi.org/10.1101/2020.10.15.340976
https://doi.org/10.1101/2020.10.15.340976
Publikováno v:
Analytical chemistry. 92(17)
Analytical methods may not have reference standards required for testing their accuracy. We postulate that the accuracy of an analytical method can be assessed in the absence of reference standards
Analytical methods may not have reference standards required for testing their accuracy. We postulate that accuracy of an analytical method can be assessed in the absence of reference standards in silico if the method is built upon deterministic proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0c4b4b32a7e9c2443917f09ccdef1a
https://doi.org/10.26434/chemrxiv.12345644.v2
https://doi.org/10.26434/chemrxiv.12345644.v2
Autor:
Sven Kochmann, Sergey N. Krylov
Publikováno v:
Lab on a Chip. 17:256-266
We present an image processing and analysis system to facilitate detailed performance analysis of free flow electrophoresis (FFE) chips. It consists of a cost-effective self-built imaging setup and a comprehensive customizable software suite. Both co