Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sven H. Giese"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Predicting chromatographic retention times (RTs) has proven beneficial in proteomics but has not yet been achieved for crosslinked peptides. Here, the authors develop an RT prediction tool for crosslinked peptides and leverage predicted RTs to increa
Externí odkaz:
https://doaj.org/article/9ab330b45697406d85ede559b5464d05
Publikováno v:
Sinn, L R, Giese, S H, Stuiver, M & Rappsilber, J 2022, ' Leveraging parameter dependencies in high-field asymmetric waveform ion-mobility spectrometry and size exclusion chromatography for proteome-wide cross-linking mass spectrometry ', Analytical Chemistry, vol. 94, no. 11, pp. 4627-4634 . https://doi.org/10.1021/acs.analchem.1c04373
Sinn, L R, Giese, S H, Stuiver, M & Rappsilber, J 2022, ' Leveraging parameter dependencies in high-field asymmetric waveform ion-mobility spectrometry and size-exclusion chromatography for proteome-wide crosslinking mass spectrometry ', Analytical Chemistry, vol. 94, no. 11, pp. 4627-4634 . https://doi.org/10.1021/acs.analchem.1c04373
Sinn, L R, Giese, S H, Stuiver, M & Rappsilber, J 2022, ' Leveraging parameter dependencies in high-field asymmetric waveform ion-mobility spectrometry and size-exclusion chromatography for proteome-wide crosslinking mass spectrometry ', Analytical Chemistry, vol. 94, no. 11, pp. 4627-4634 . https://doi.org/10.1021/acs.analchem.1c04373
Ion-mobility spectrometry shows great promise to tackle analytically challenging research questions by adding another separation dimension to liquid chromatography-mass spectrometry. The understanding of how analyte properties influence ion mobility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797e4230123a2b88e0a1eca609f3cf56
https://hdl.handle.net/20.500.11820/680d6b13-3959-4877-b31e-0f8a56d87eb6
https://hdl.handle.net/20.500.11820/680d6b13-3959-4877-b31e-0f8a56d87eb6
Mass spectrometry-based proteomics provides a holistic snapshot of the entire protein set of living cells on a molecular level. Currently, only a few deep learning approaches exist that involve peptide fragmentation spectra, which represent partial s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8aa1eb9a127c091109aae8e4970100
https://doi.org/10.1038/s42256-022-00467-7
https://doi.org/10.1038/s42256-022-00467-7
Autor:
Alice Wittig, Fábio Miranda, Martin Hölzer, Tom Altenburg, Jakub M Bartoszewicz, Sebastian Beyvers, Marius A Dieckmann, Ulrich Genske, Sven H Giese, Melania Nowicka, Hugues Richard, Henning Schiebenhoefer, Anna-Juliane Schmachtenberg, Paul Sieben, Ming Tang, Julius Tembrockhaus, Bernhard Y Renard, Stephan Fuchs
Publikováno v:
Bioinformatics (Oxford, England). 38(17)
Summary The ongoing pandemic caused by SARS-CoV-2 emphasizes the importance of genomic surveillance to understand the evolution of the virus, to monitor the viral population, and plan epidemiological responses. Detailed analysis, easy visualization a
Autor:
Alice Wittig, Fábio Miranda, Martin Hölzer, Tom Altenburg, Jakub M. Bartoszewicz, Sebastian Beyvers, Marius A. Dieckmann, Ulrich Genske, Sven H. Giese, Melania Nowicka, Hugues Richard, Henning Schiebenhoefer, Anna-Juliane Schmachtenberg, Paul Sieben, Ming Tang, Julius Tembrockhaus, Bernhard Y. Renard, Stephan Fuchs
The SARS-CoV-2 pandemic underlined the importance of molecular surveillance to track the evolution of the virus and inform public health interventions. Fast analysis, easy visualization and convenient filtering of the latest virus sequences are essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65f01f540d0bf33085eecc11ca03a86c
https://doi.org/10.1101/2021.02.03.429146
https://doi.org/10.1101/2021.02.03.429146
Publikováno v:
Analytical Chemistry
Cross-linking mass spectrometry draws structural information from covalently linked peptide pairs. When these links do not match to previous structural models, they may indicate changes in protein conformation. Unfortunately, such links can also be t
Crosslinking mass spectrometry draws structural information from covalently-linked peptide pairs. When these links do not match to previous structural models, they may indicate changes in protein conformation. Unfortunately, such links can also be th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc001a4c9b75f96787500bc911e8cf1d
Autor:
Marta Barbon, Francis J. O’Reilly, Sven H. Giese, Colin W. Combe, Christian Speck, Therese Dau, Markus R. Eisele, Zhuo A. Chen, Lutz Fischer, Michael Bohlke-Schneider, Martin Graham, Wolfgang Baumeister, Adam Belsom, Juri Rappsilber, Marta Mendes
Publikováno v:
Mendes, M L, Fischer, L, Chen, Z A, Barbon, M, O'Reilly, F J, Giese, S H, Bohlke-Schneider, M, Belsom, A, Dau, T, Combe, C W, Graham, M, Eisele, M R, Baumeister, W, Speck, C & Rappsilber, J 2019, ' An integrated workflow for crosslinking mass spectrometry ', Molecular Systems Biology, vol. 15, no. 9, e8994 . https://doi.org/10.15252/msb.20198994
MOLECULAR SYSTEMS BIOLOGY
Molecular Systems Biology, Vol 15, Iss 9, Pp n/a-n/a (2019)
Molecular Systems Biology
MOLECULAR SYSTEMS BIOLOGY
Molecular Systems Biology, Vol 15, Iss 9, Pp n/a-n/a (2019)
Molecular Systems Biology
We present a concise workflow to enhance the mass spectrometric detection of cross-linked peptides by introducing sequential digestion and the cross-link identification software Xi. Sequential digestion enhances peptide detection by shortening long t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77daded97947d6d10ac7e6fab8219114
Publikováno v:
Journal of Proteome Research
Lenz, S, Giese, S H, Fischer, L & Rappsilber, J 2018, ' In-Search Assignment of Monoisotopic Peaks Improves the Identification of Cross-Linked Peptides ', Journal Of Proteome Research, vol. 17, no. 11, pp. 3923-3931 . https://doi.org/10.1021/acs.jproteome.8b00600
Lenz, S, Giese, S H, Fischer, L & Rappsilber, J 2018, ' In-Search Assignment of Monoisotopic Peaks Improves the Identification of Cross-Linked Peptides ', Journal Of Proteome Research, vol. 17, no. 11, pp. 3923-3931 . https://doi.org/10.1021/acs.jproteome.8b00600
Cross-linking/mass spectrometry (CLMS) has undergone a maturation process akin to standard proteomics by adapting key methods such as false discovery rate control and quantification. A seldom-used search setting in proteomics is the consideration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb949559896fd7e160b2cda50a42b85
Autor:
Bernhard Y. Renard, Ozge Karayel, Zeynep Cansu Üretmen Kagıalı, Nurcan Tuncbag, Chi-Kuo Hu, Erdem Sanal, Ayse Nur Polat, Nurhan Özlü, Sven H. Giese
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports
Scientific Reports
The successful completion of cytokinesis requires the coordinated activities of diverse cellular components including membranes, cytoskeletal elements and chromosomes that together form partly redundant pathways, depending on the cell type. The bioch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da64974171dc8af20f94983609593d5b
https://aperta.ulakbim.gov.tr/record/110300
https://aperta.ulakbim.gov.tr/record/110300