Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sven Erik Ojavee"'
Autor:
Anna Tisler, Andres Võrk, Martin Tammemägi, Sven Erik Ojavee, Mait Raag, Aleksandra Šavrova, Mari Nygård, Jan F. Nygård, Mindaugas Stankunas, Anda Kivite-Urtane, Anneli Uusküla
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Transitioning to an individualized risk-based approach can significantly enhance cervical cancer screening programs. We aimed to derive and internally validate a prediction model for assessing the risk of cervical intraepithelial neoplasia g
Externí odkaz:
https://doaj.org/article/29f2361c90054d738c78d6715154456f
Autor:
Anna Tisler, Anneli Uusküla, Sven Erik Ojavee, Kristi Läll, Estonian Biobank research team, Triin Laisk
Publikováno v:
Infectious Agents and Cancer, Vol 18, Iss 1, Pp 1-9 (2023)
Abstract The era of precision medicine requires the achievement of accurate risk assessment. Polygenic risk scores (PRSs) have strong potential for increasing the benefits of nationwide cancer screening programs. The current pool of evidence on the r
Externí odkaz:
https://doaj.org/article/83c422f136764465b70614313f0cd0b9
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background The World Health Organisation (WHO) calls for the elimination of cervical cancer (CC) as a public health issue. To achieve elimination, efforts must be aligned and accelerated. Women living with HIV (WLWH) have excess risk for dev
Externí odkaz:
https://doaj.org/article/4ee81bd6b03f43239a162e7e4e173f27
Autor:
Robert F. Hillary, Daniel Trejo-Banos, Athanasios Kousathanas, Daniel L. McCartney, Sarah E. Harris, Anna J. Stevenson, Marion Patxot, Sven Erik Ojavee, Qian Zhang, David C. Liewald, Craig W. Ritchie, Kathryn L. Evans, Elliot M. Tucker-Drob, Naomi R. Wray, Allan F. McRae, Peter M. Visscher, Ian J. Deary, Matthew R. Robinson, Riccardo E. Marioni
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-15 (2020)
Abstract Background The molecular factors which control circulating levels of inflammatory proteins are not well understood. Furthermore, association studies between molecular probes and human traits are often performed by linear model-based methods
Externí odkaz:
https://doaj.org/article/19534d9a8ec84e659ab1448d4b67f986
Publikováno v:
The American Journal of Human Genetics. 109:2009-2017
Theory for liability-scale models of the underlying genetic basis of complex disease provides an important way to interpret, compare and understand results generated from biological studies. In particular, liability models facilitate an understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b0726304d08d3f9df5ae09393fbc73
https://doi.org/10.1016/j.ajhg.2022.09.011
https://doi.org/10.1016/j.ajhg.2022.09.011
Autor:
Marion Patxot, Miloš Stojanov, Sven Erik Ojavee, Rosanna Pescini Gobert, Zoltán Kutalik, Mathilde Gavillet, David Baud, Matthew R. Robinson
Publikováno v:
European journal of haematologyREFERENCES. 109(5)
About 800 women die every day worldwide from pregnancy-related complications, including excessive blood loss, infections and high-blood pressure (World Health Organization, 2019). To improve screening for high-risk pregnancies, we set out to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad6ab0941431c2ae740e9dc9a4ccc7f
https://pubmed.ncbi.nlm.nih.gov/36059200
https://pubmed.ncbi.nlm.nih.gov/36059200
Autor:
Kristi Läll, Etienne J. Orliac, Marion Patxot, Zoltán Kutalik, Athanasios Kousathanas, Reedik Mägi, Sven Erik Ojavee, Daniel Trejo Banos, Matthew R. Robinson, Krista Fischer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature communications, vol. 12, no. 1, pp. 2337
Nature Communications
Nature communications, vol. 12, no. 1, pp. 2337
Nature Communications
While recent advancements in computation and modelling have improved the analysis of complex traits, our understanding of the genetic basis of the time at symptom onset remains limited. Here, we develop a Bayesian approach (BayesW) that provides prob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1db646a40ae5f974debd9ff3bb6990
https://doaj.org/article/98babe5c070d44148cee67c1123085fa
https://doaj.org/article/98babe5c070d44148cee67c1123085fa
Autor:
Daniel L. McCartney, Athanasios Kousathanas, Qian Zhang, Naomi R. Wray, Marion Patxot, Riccardo E. Marioni, Daniel Trejo-Banos, Ian J. Deary, Matthew R. Robinson, Craig W. Ritchie, Robert F. Hillary, Sven Erik Ojavee, Allan F. McRae, David C. Liewald, Peter M. Visscher, Anna J. Stevenson, Elliot M. Tucker-Drob, Kathryn L. Evans, Sarah E. Harris
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-15 (2020)
Genome Medicine
Hillary, R, Trejo-Banos, D, Kousathanas, A, McCartney, D L, Harris, S E, Stevenson, A J, Patxot, M, Ojavee, S E, Zhang, Q, Liewald, D C, Ritchie, C W, Evans, K L, Tucker-Drob, E M, Wray, N R, McRae, A F, Visscher, P M, Deary, I J, Robinson, M R & Marioni, R E 2020, ' Multi-method genome-and epigenome-wide studies of inflammatory protein levels in healthy older adults ', Genome Medicine, vol. 12, 60 . https://doi.org/10.1186/s13073-020-00754-1
Genome medicine, vol. 12, no. 1, pp. 60
Genome Medicine
Hillary, R, Trejo-Banos, D, Kousathanas, A, McCartney, D L, Harris, S E, Stevenson, A J, Patxot, M, Ojavee, S E, Zhang, Q, Liewald, D C, Ritchie, C W, Evans, K L, Tucker-Drob, E M, Wray, N R, McRae, A F, Visscher, P M, Deary, I J, Robinson, M R & Marioni, R E 2020, ' Multi-method genome-and epigenome-wide studies of inflammatory protein levels in healthy older adults ', Genome Medicine, vol. 12, 60 . https://doi.org/10.1186/s13073-020-00754-1
Genome medicine, vol. 12, no. 1, pp. 60
BACKGROUND: The molecular factors which control circulating levels of inflammatory proteins are not well understood. Furthermore, association studies between molecular probes and human traits are often performed by linear model-based methods which ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961028c050bbfa93f082ce28b0072fd9
http://link.springer.com/article/10.1186/s13073-020-00754-1
http://link.springer.com/article/10.1186/s13073-020-00754-1
Autor:
Kristi Läll, Etienne J. Orliac, Sven Erik Ojavee, Peter M. Visscher, Reedik Mägi, Daniel Trejo Banos, Matthew R. Robinson
Genetically informed, deep-phenotyped biobanks are an important research resource and it is imperative that the most powerful, versatile, and efficient analysis approaches are used. Here, we apply our recently developed Bayesian grouped mixture of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6045777ceff598a5f939c264fcfc2ce1
https://doi.org/10.1101/2021.08.12.456099
https://doi.org/10.1101/2021.08.12.456099
Autor:
Liis Starkopf, Sven Erik Ojavee, Stephan M. Jakob, Annika Reintam Blaser, O. Rooijackers, Jan Wernerman, Joel Starkopf, Michael Hiesmayr, Alastair Forbes, Martin Padar
Publikováno v:
Clinical nutrition ESPEN. 45
Summary Background and aims Plasma citrulline and intestinal fatty acid binding protein (I-FABP) are biomarkers reflecting enterocyte function and intestinal mucosal injury. The aim was to describe daily dynamics of citrulline and I-FABP concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec140d16df12c116af71d7ee0e2de93b
https://pubmed.ncbi.nlm.nih.gov/34620335
https://pubmed.ncbi.nlm.nih.gov/34620335