Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sven Erickson"'
Autor:
Anders Lehmann, Thore Johansson, A. Jonas Ekstrand, Christophe Quéva, Anders Edlund, Susanne Elg, Sven Erickson, Jan P. Mattsson, Marianne Bremner-Danielsen
Publikováno v:
British Journal of Pharmacology. 140:315-322
1. Activation of GABA(B) receptors evokes hypothermia in wildtype (GABA(B(1))+/+) but not in GABA(B) receptor knockout (GABA(B(1))-/-) mice. The aim of the present study was to determine the hypothermic and behavioural effects of the putative GABA(B)
Autor:
Sampsa Matikainen, Stefan Einhorn, Lena Thyrell, Sven Erickson, Olle Sangfelt, Ilkka Julkunen, Dan Grandér
Publikováno v:
European Journal of Biochemistry. 269:29-37
It has previously been shown that IFN-alpha is a potent inhibitor of IL-2 induced proliferation in primary T-lymphocytes, by selectively abrogating the downstream effects of IL-2 on the core cell cycle machinery regulating the G1/S transition. Theore
Autor:
Dawei Xu, Astrid Gruber, Michael Szeps, Dan Grandér, Sven Erickson, Olle Sangfelt, Stefan Einhorn, Pavel Pisa
Publikováno v:
Blood. 96:4313-4318
Recently, the derepressed expression of the catalytic subunit of telomerase, human telomerase reverse transcriptase (hTERT), the enzyme that elongates telomeres, has been implicated as an important step in the immortalization process. The exact regul
Autor:
Anna Gustafsson, Stefan Einhorn, Juan Castro, Thomas Heiden, Sven Erickson, Olle Sangfelt, Dan Grandér
Publikováno v:
Oncogene. 18:2798-2810
One prominent effect of IFNs is their cell growth-inhibitory activity. The mechanism behind this inhibition of proliferation is still not fully understood. In this study, the effect of IFN-alpha treatment on cell cycle progression has been analysed i
Publikováno v:
Oncogene. 17:595-602
Little is known about the molecular background to senescence in T-lymphocytes. In fibroblast systems replicative senescence has been shown to correlate with a number of changes in the expression of the proteins normally regulating progression through
Publikováno v:
Leukemialymphoma. 44(6)
One prominent activity of Interferons (IFNs) is their ability to induce cell cycle arrest, and this effect has furthermore been proposed to be of major importance in mediating the clinical antitumor activity of IFNs. In several IFN sensitive establis
Autor:
Sven, Erickson, Sampsa, Matikainen, Lena, Thyrell, Olle, Sangfelt, Ilkka, Julkunen, Stefan, Einhorn, Dan, Grandér
Publikováno v:
European journal of biochemistry. 269(1)
It has previously been shown that IFN-alpha is a potent inhibitor of IL-2 induced proliferation in primary T-lymphocytes, by selectively abrogating the downstream effects of IL-2 on the core cell cycle machinery regulating the G1/S transition. Theore
Autor:
Olle Sangfelt, Stefan Einhorn, Juan Castro, Lena Thyrell, Dan Grandér, Sven Erickson, Boris Zhivotovsky, Katja Pokrovskaja
Publikováno v:
Oncogene. 21(8)
Interferon alpha (IFNalpha) has been used in the treatment of several types of cancer for almost 30 years, yet the mechanism(s) responsible for its anti-tumoral action remains unknown. A variety of cellular responses, including inhibition of cell gro
Publikováno v:
Frontiers in Bioscience. 5:d479
The interferons (IFNs) are a group of cytokines, which in addition to their antiviral activity are capable of modulating a variety of cellular responses. One such prominent effect of IFNs is their potent antimitogenic action, which can be observed bo