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pro vyhledávání: '"Sven E. Templer"'
Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals
Autor:
Shuhei Nakamura, Özlem Karalay, Philipp S. Jäger, Makoto Horikawa, Corinna Klein, Kayo Nakamura, Christian Latza, Sven E. Templer, Christoph Dieterich, Adam Antebi
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Removal of the C. elegans germline substantially increases organismal lifespan. Here, Nakamura et al. show that the transcription factors MML-1 and MXL-2 coordinate this process in that they reduce TOR signalling and increase autophagy by regulating
Externí odkaz:
https://doaj.org/article/d64ac3f9db434a949312fa7d63fb441c
