Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sven E. Templer"'
Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals
Autor:
Shuhei Nakamura, Özlem Karalay, Philipp S. Jäger, Makoto Horikawa, Corinna Klein, Kayo Nakamura, Christian Latza, Sven E. Templer, Christoph Dieterich, Adam Antebi
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Removal of the C. elegans germline substantially increases organismal lifespan. Here, Nakamura et al. show that the transcription factors MML-1 and MXL-2 coordinate this process in that they reduce TOR signalling and increase autophagy by regulating
Externí odkaz:
https://doaj.org/article/d64ac3f9db434a949312fa7d63fb441c
Autor:
Hornik, Kurt1 Kurt.Hornik@R-project.org, Zeileis, Achim2 Achim.Zeileis@R-project.org
Publikováno v:
R Journal. Jun2014, Vol. 6 Issue 1, p186-220. 35p.
Publikováno v:
Nucleic Acids Research; May2015, Vol. 43 Issue 9, p4687-4700, 14p, 1 Diagram, 6 Graphs