Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sven E. Boden"'
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 32:1069-1074
In order to elucidate the role of mitogen-activated protein kinase kinase (MEK-1/2) in 5-lipoxygenase (5-LO) activation we studied the N -formyl-methionyl-leucyl-phenylalanine (fMLP)-induced 5-LO translocation in human blood neutrophils (PMNs). In no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005f3e2e691e1dbc9b5183abd5238d58
https://doi.org/10.1016/s1357-2725(00)00049-2
https://doi.org/10.1016/s1357-2725(00)00049-2
Publikováno v:
Molecular pharmacology. 60(2)
Commercially available extracts from Boswellia serrata resin used as anti-inflammatory drugs or phytonutrients show paradoxical concentration-dependent potentiating and inhibitory actions on 5-lipoxygenase (5-LO) product synthesis in stimulated PMNs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6bab769159468ba7d73ffe56c34cad5
https://pubmed.ncbi.nlm.nih.gov/11455013
https://pubmed.ncbi.nlm.nih.gov/11455013
Autor:
Norbert Senninger, Christoph Anthoni, Christian F. Krieglstein, H. U. Spiegel, Emile Rijcken, M. G. Laukötter, G. Schürmann, Sven E. Boden, Stephan Schweizer, Hasan Safayhi
Publikováno v:
International journal of colorectal disease. 16(2)
The gum resin extract from Boswellia serrata (H15), an herbal product, was recently shown to have positive therapeutic effects in inflammatory bowel disease (IBD). However, the mechanisms and constituents responsible for these effects are poorly unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e84cbf10c434223a255a9655527e43
https://pubmed.ncbi.nlm.nih.gov/11355324
https://pubmed.ncbi.nlm.nih.gov/11355324
Autor:
A. F. W. von Brocke, Hermann P. T. Ammon, Stephan Schweizer, Sven E. Boden, Hasan Safayhi, Ernst Bayer
Publikováno v:
Journal of natural products. 63(8)
Pentacyclic triterpenes from the 11-keto-boswellic acid series were identified as the active principal ingredients of Boswellia resin, inhibiting the key enzyme of leukotriene biosynthesis, 5-lipoxygenase (5-LO). Of the genuine boswellic acids hither
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076e2768360ab266f3d3909ef1850609
https://pubmed.ncbi.nlm.nih.gov/10978197
https://pubmed.ncbi.nlm.nih.gov/10978197
Publikováno v:
Planta medica. 66(2)
Preparations from the gum of Boswellia spec. have been used in the traditional medicine for the treatment of inflammatory diseases. Extracts from B. serrata gum were shown to inhibit leukotriene biosynthesis by impairing the 5-lipoxygenase (5-LO) act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3570e9d704f248749b0f8ff84f188afd
https://pubmed.ncbi.nlm.nih.gov/10763581
https://pubmed.ncbi.nlm.nih.gov/10763581
Publikováno v:
European journal of biochemistry. 256(2)
AKBA (acetyl-11-keto-beta-boswellic acid), a natural pentacyclic triterpene, is an orally active leukotriene-synthesis inhibitor, which acts by a 5-lipoxygenase-directed, non-redox, non-competitive mechanism. It is the only leukotriene-synthesis inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112ba925a98ff8ae1a699017de592190
https://pubmed.ncbi.nlm.nih.gov/9760176
https://pubmed.ncbi.nlm.nih.gov/9760176