Výsledky vyhledávání - "Sven Brucker"

Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy

Autor: Ingrid R. Vetter, Sarah Jenrich, Klaus Gerwert, Till Rudack, Carsten Kötting, Sven Brucker

Publikováno v: Journal of Biological Chemistry. 290:24079-24090

Small GTPases regulate key processes in cells. Malfunction of their GTPase reaction by mutations is involved in severe diseases. Here, we compare the GTPase reaction of the slower hydrolyzing GTPase Ran with Ras. By combination of time-resolved FTIR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3a95e322d26e040bd902c6247b0dad
https://doi.org/10.1074/jbc.m115.648071

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Systematic approach to group-specific isotopic labeling of proteins for vibrational spectroscopy

Autor: Angela Kallenbach, Sven Brucker, Klaus Gerwert, Carsten Kötting, Helmut E. Meyer, Bettina Warscheid

Publikováno v: Vibrational Spectroscopy. 48:28-36

Group-specific isotopic labeling of proteins using stable isotopes such as 15 N, 13 C, or 2 H is a widely applied method for the accurate assignment of signals in FTIR spectroscopy. In this work, we report a systematic study on the metabolic incorpor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78d8b15c4821d0238b8e74a1704bdd35
https://doi.org/10.1016/j.vibspec.2007.11.003

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Tyr39 of ran preserves the Ran.GTP gradient by inhibiting GTP hydrolysis

Autor: Sven Brucker, Carsten Kötting, Klaus Gerwert

Publikováno v: Journal of molecular biology. 401(1)

Ran is a member of the superfamily of small GTPases, which cycle between a GTP-bound "on" and a GDP-bound "off" state. Ran regulates nuclear transport. In order to maintain a gradient of excess Ran.GTP within the nucleoplasm and excess Ran.GDP within

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ae66f1a7f124c72e928681e70796b7
https://pubmed.ncbi.nlm.nih.gov/20609434

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Mechanistic studies of the Ras-Superfamily by Time-Resolved FTIR-Spectroscopy

Autor: Angela Kallenbach, Yan Suveyzdis, Klaus Gerwert, Marco Blessenohl, Sven Brucker, Carsten Ktting, Partha Chakrabarti, Katrin Beckmann, Carolin Eichholz

Publikováno v: GBM Annual Fall meeting M�nster 2004. 2004

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9af4a21f231d04e08f2c66da936baab
https://doi.org/10.1240/sav_gbm_2004_h_000710

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