Zobrazeno 1 - 10
of 255
pro vyhledávání: '"Sven Brandau"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/4609f53de0444934ace64d0a0cc10c40
Immunoglobulins and serum proteins impair anti-tumor NK cell effector functions in malignant ascites
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMalignant ascites indicates ovarian cancer progression and predicts poor clinical outcome. Various ascites components induce an immunosuppressive crosstalk between tumor and immune cells, which is poorly understood. In our previous study,
Externí odkaz:
https://doaj.org/article/fb001130642741d6af7e684fe2f83b55
Autor:
Antonio Hrvat, Mathias Schmidt, Bernd Wagner, Denise Zwanziger, Rainer Kimmig, Lothar Volbracht, Sven Brandau, Nina Mallmann-Gottschalk
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Malignant ascites commonly occurs in advanced or recurrent stages of epithelial ovarian cancer during peritoneal carcinomatosis and is correlated with poor prognosis. Due to its complex composition of cellular and acellular compon
Externí odkaz:
https://doaj.org/article/e35492f228ef4d518541830ae82afb79
Autor:
Eric Deuss, Cornelius Kürten, Lara Fehr, Laura Kahl, Stefanie Zimmer, Julian Künzel, Roland H. Stauber, Stephan Lang, Timon Hussain, Sven Brandau
Publikováno v:
Cancers, Vol 16, Iss 11, p 2103 (2024)
For practical reasons, in many studies PD-L1 expression is measured by combined positive score (CPS) from a single tumor sample. This does not reflect the heterogeneity of PD-L1 expression in head and neck squamous cell carcinoma (HNSCC). We investig
Externí odkaz:
https://doaj.org/article/c56c3982fa444d20abe15c4e6b97dbf4
Autor:
Anna Malyshkina, Wibke Bayer, Philip Podschwadt, Lucas Otto, Zehra Karakoese, Kathrin Sutter, Kirsten Bruderek, Baoxiao Wang, Kerry J Lavender, Mario L Santiago, Pia Madeleine Leipe, Carina Elsner, Stefan Esser, Sven Brandau, Matthias Gunzer, Ulf Dittmer
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011725 (2023)
Antiretroviral therapy (ART) transformed HIV from a life-threatening disease to a chronic condition. However, eliminating the virus remains an elusive therapy goal. For several decades, Friend virus (FV) infection serves as a murine model to study re
Externí odkaz:
https://doaj.org/article/a81ed88024bb4e859ce8d252a4270370
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Mesenchymal stromal cells (MSCs) and their extracellular vesicles (EVs) exert profound anti-inflammatory and regenerative effects in inflammation and tissue damage, which makes them an attractive tool for cellular therapies. In this study we have ass
Externí odkaz:
https://doaj.org/article/0e206b3282bd4b2ba21905a110654e43
Autor:
Luca Cassetta, Pedro Rodrigues, Toni Andreu, Bruno Botta, Sven Brandau, Chrissie Brierley, Clive Wilson, Inga Dadeshidze, Lucia Forzi, Federica Ortelli, Mafalda Quintas
Publikováno v:
Research Ideas and Outcomes, Vol 6, Iss , Pp 1-15 (2020)
Cancer has been for many years the second leading cause of mortality right after cardiovascular diseases, representing 25% of all the deaths reported yearly and this tendency is expected to increase. Although the recent public health emergency caused
Externí odkaz:
https://doaj.org/article/90e7161754c7411d8286d87b2c5eca7c
Autor:
Antonio Hrvat, Mathias Schmidt, Martin Obholzer, Sonja Benders, Sebastian Kollenda, Peter A. Horn, Matthias Epple, Sven Brandau, Nina Mallmann-Gottschalk
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Calcium phosphate nanoparticles (CaP-NPs) are biodegradable carriers that can be functionalized with biologically active molecules. As such, they are potential candidates for delivery of therapeutic molecules in cancer therapies. In this context, it
Externí odkaz:
https://doaj.org/article/c9a5bf293f554bd58601bd49bbb32de0
Autor:
Katharina Henze, Monika Herten, Marcel Haversath, André Busch, Sven Brandau, Alexander Hackel, Stefanie B. Flohé, Marcus Jäger
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Background During joint replacement, surgical vacuum suction guarantees a sufficient overview on the situs. We assume high concentrations of mesenchymal stromal cells (MSCs) on surgical vacuum filters. We compared the in vitro proliferative
Externí odkaz:
https://doaj.org/article/282e4386a2f8465cb1e1845cbb2684a4
Autor:
Ang Lin, Sven Brandau, Stephan Lang, Luca Cassetta, Kirsten Bruderek, Joanna Skrzeczynska-Moncznik, Oktawia Osiecka, Xiaoying Hu, Ida Marie Rundgren, Kim Santegoets, Utku Horzum, Ana Godinho-Santos, Gennadiy Zelinskyy, Thalia Garcia-Tellez, Sunčica Bjelica, Bartłomiej Taciak, Astrid Olsnes Kittang, Benedikt Höing, Michael Dixon, Verena Müller, Jochen Sven Utikal, Derya Karakoç, Kerim Bora Yilmaz, Emilia Górka, Olympia Evdoxia Anastasiou, Christine Bourgeois, Robert Badura, Monika Kapinska-Mrowiecka, Mirjana Gotic, Mark ter Laan, Esther Kers-Rebel, Magdalena Król, Juan Francisco Santibañez, Michaela Müller-Trutwin, Ulf Dittmer, Ana Espada de Sousa, Güneş Esendağlı, Gosse Adema, Karin Loré, Elisabeth Ersvær, Viktor Umansky, Jeffrey W Pollard, Joanna Cichy
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Myeloid-derived suppressor cells (MDSC) are a functional myeloid cell subset that includes myeloid cells with immune suppressive properties. The presence of MDSC has been reported in the peripheral blood of patients with several malignant
Externí odkaz:
https://doaj.org/article/a204127dcd8f4fbba35c1dcd217e919e