Výsledky vyhledávání

Synthesis of an Anti-CD7 Recombinant Immunotoxin Based on PE24 in CHO and

Autor: Simon K, Krebs, Marlitt, Stech, Felix, Jorde, Nathanaël, Rakotoarinoro, Franziska, Ramm, Sophie, Marinoff, Sven, Bahrke, Antje, Danielczyk, Doreen A, Wüstenhagen, Stefan, Kubick

Publikováno v: International journal of molecular sciences. 23(22)

Recombinant immunotoxins (RITs) are an effective class of agents for targeted therapy in cancer treatment. In this article, we demonstrate the straight-forward production and testing of an anti-CD7 RIT based on PE24 in a prokaryotic and a eukaryotic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8e39a778833f2b6cecfabbe1de5b258
https://pubmed.ncbi.nlm.nih.gov/36430170

Zobrazit plný text záznamu

781 GT-001 - anti-Lewis Y antibody with superior fine-specificity and reduced off-target binding

Autor: Patrik Kehler, Johanna Gellert, Sven Bahrke, Christoph Goletz, Lisa Weiß, Anika Jaekel, Flechner Anke, Timo Lischke, Antje Danielczyk, Evelyn Hartung

Publikováno v: Journal for ImmunoTherapy of Cancer. 9:A816-A816

BackgroundThe Lewis Y (CD174) carbohydrate antigen is widely expressed in primary and metastatic epithelial tumors like colon, lung, ovarian, and breast. Targeting Lewis Y for cancer therapy was pursued before, however, other anti-Lewis Y antibodies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1f3bd93c06f8eb92339049341a1dd23
https://doi.org/10.1136/jitc-2021-sitc2021.781

Zobrazit plný text záznamu

Partially acetylated chitooligosaccharides bind to YKL-40 and stimulate growth of human osteoarthritic chondrocytes

Autor: Pétur Henry Petersen, Chuen-How Ng, Martin G. Peter, Jon M. Einarsson, Johannes Gislason, Olafur E. Sigurjonsson, Halldór Jónsson, Finnbogi R. Thormodsson, Bjarni Sigurdsson, Sven Bahrke

Publikováno v: Biochemical and Biophysical Research Communications. 434:298-304

Recent evidences indicating that cellular kinase signaling cascades are triggered by oligomers of N-acetylglucosamine (ChOS) and that condrocytes of human osteoarthritic cartilage secrete the inflammation associated chitolectin YKL-40, prompted us to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4203f4234acd2ff03d94db410a0b5899
https://doi.org/10.1016/j.bbrc.2013.02.122

Zobrazit plný text záznamu

Quantitative sequencing of complex mixtures of heterochitooligosaccharides by vMALDI-linear ion trap mass spectrometry

Autor: Sven Bahrke, Martin G. Peter, Sophie Haebel

Heterochitooligosaccharides possess interesting biological properties. Isobaric mixtures of such linear heterochitooligosaccharides can be obtained by chemical or enzymatic degradation of chitosan. However, the separation of such mixtures is a challe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc299cd12eb3df6c4e9549c02a89fa3f
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/31204

Zobrazit plný text záznamu

Identification of a high-affinity-binding oligosaccharide by (+) nanoelectrospray quadrupole time-of-flight tandem mass spectrometry of a noncovalent enzyme-ligand complex

Autor: Vincent G. H. Eijsink, Alina D. Zamfir, F. Henning Cederkvist, Morten Sørlie, Sven Bahrke, Jasna Peter-Katalinić, Martin G. Peter

Oligosaccharides are of current interest as targets for the development of novel pharmaceuticals and plant-growth regulators. For example, so-called heterochitooligosaccharides, which are composed of N-acetylglucosamine (GlcNAc or A) and glucosamine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c59e8fb7522db69fd6bbbd97e1c07ae
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/30777

Zobrazit plný text záznamu

SEQUENCE ANALYSIS OF CHITOOLIGOSACCHARIDES BY MALDI PSD MASS SPECTROMETRY

Autor: Jon M. Einarsson, Sven Bahrke, Martin G. Peter, Matthias C. Letzel, Sophie Haebel, Johannes Gislason, Jasna Peter-Katalinic

Publikováno v: XXIst International Carbohydrate Symposium 2002.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91f2bdea145d96bb16de8caadf869a1e
https://doi.org/10.1100/tsw.2002.544

Zobrazit plný text záznamu

Sequence analysis of chitooligosaccharides by matrix-assisted laser desorption ionization postsource decay mass spectrometry

Autor: Jasna Peter-Katalinić, Matthias C. Letzel, Jon M. Einarsson, Martin G. Peter, Johannes Gislason, Sven Bahrke, Sophie Haebel

Chitin/chitosan oligosaccharides composed of 2-acetamido-2-deoxy-D-glucopyranose (GlcNAc) and/or 2-amino-2-deoxy-D-glucopyranose (GlcN) were prepared by chemical degradation of chitin or chitosan and separated by gel permeation chromatography. Oligos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4107de0d8b1ad41822a580f62daddf48
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/17375

Zobrazit plný text záznamu

Akademický článek

Identification of a High-Affinity-Binding Oligosaccharide by (+) Nanoelectrospray Quadrupole Time-of-Flight Tandem Mass Spectrometry of a Noncovalent Enzyme–Ligand ComplexThis work was supported by the Deutsche Forschungsgemeinschaft (Sonderforschungsbereich 492, project Z2 to J.P.K. and grant Pe 264/18-1 to M.G.P.) and by the Norwegian Research Council (grant 140497/420 to M.S. and V.G.H.E.)

Autor: F. Henning Cederkvist, Alina D. Zamfir, Sven Bahrke, Vincent G. H. Eijsink, Morten Sørlie, Jasna Peter-Katalinić, Martin G. Peter

Publikováno v: Angewandte Chemie; Mar2006, Vol. 118 Issue 15, p2489-2494, 6p

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání