Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sven Ansorge"'
Autor:
Angelo Luis Caron, Virgínia Picanço-Castro, Sven Ansorge, Dimas Tadeu Covas, Amine Kamen, Kamilla Swiech
Publikováno v:
Brazilian Archives of Biology and Technology, Vol 58, Iss 6, Pp 923-928 (2015)
ABSTRACT Lentiviral vector-mediated gene transfer offers several advantages over other gene delivery vectors when considering gene and cell therapy applications. However, using these therapies in clinical applications involves large-scale vector prod
Externí odkaz:
https://doaj.org/article/c18fbe14953e4327b53dc62e57220d64
Autor:
Aziza P Manceur, Wei Zou, Anne Marcil, Eric Paquet, Christine Gadoury, Bozena Jaentschke, Xuguang Li, Emma Petiot, Yves Durocher, Jason Baardsnes, Manuel Rosa-Calatrava, Sven Ansorge, Amine A Kamen
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180314 (2017)
Vaccination is the most effective course of action to prevent influenza. About 150 million doses of influenza vaccines were distributed for the 2015-2016 season in the USA alone according to the Centers for Disease Control and Prevention. Vaccine dos
Externí odkaz:
https://doaj.org/article/84d646f3a5fe4208a105f5bca7c272fb
Autor:
Chun Fang, Shen, Sonia, Tremblay, Catherine, Sabourin-Poirier, Elodie, Burney, Sophie, Broussau, Aziza, Manceur, Anja, Rodenbrock, Robert, Voyer, Martin, Loignon, Sven, Ansorge, Rénald, Gilbert
Publikováno v:
Bioprocess and Biosystems Engineering. 45:1267-1280
The growing interest in the use of lentiviral vectors (LVs) for various applications has created a strong demand for large quantities of vectors. To meet the increased demand, we developed a high cell density culture process for production of LV usin
Publikováno v:
Cell and Gene Therapy Insights. 5:1719-1725
Autor:
Rénald Gilbert, Claire Guilbault, Amine Kamen, Sven Ansorge, S. Mehdy Elahi, Xiuling Li, Chun Fang Shen
Publikováno v:
Vaccine. 37:6996-7002
Vero cells are considered as the most widely accepted continuous cell line by the regulatory authorities (such as WHO) for the manufacture of viral vaccines for human use. The growth of Vero cells is anchorage-dependent. Scale-up and manufacturing in
Autor:
Rénald Gilbert, Alina Venereo-Sanchez, Kelly M. Fulton, Amine Kamen, Olivier Henry, Susan M. Twine, Krisztina Koczka, Sven Ansorge, Parminder S. Chahal
Publikováno v:
Vaccine. 37:7100-7107
One of the concerns associated with the use of influenza virus-like particles (VLPs) as vaccine candidate or delivery system is their heterogeneous composition. Enveloped VLPs take up the host cell membrane at the budding site carrying out not only t
Autor:
Jannie Perdersen, Parminder S. Chahal, Stéphane Lanthier, Gary P. Kobinger, Sascha Kiesslich, Hiva Azizi, Jean-François Gélinas, Amine Kamen, Sven Ansorge, Rénald Gilbert
Publikováno v:
Vaccine. 37:6624-6632
Ebola virus disease is an urgent international priority. Promising results for several vaccine candidates have been reported in non-human primate studies and clinical trials with the most promising being the rVSV-ZEBOV vaccine. In this study, we soug
Publikováno v:
Cell and Gene Therapy Insights. 5:949-970
Viral vectors are required as gene delivery vehicles for cell and gene therapies that provide transformative options for previously intractable human diseases, including diverse genetic, immunologic, neurodegenerative, ocular, cardiovascular diseases
Autor:
Michel Gilbert, Denis Brochu, Olivier Henry, Michel Perrier, Kahina Mellahi, Sven Ansorge, Yves Durocher
Publikováno v:
Bioprocess and Biosystems Engineering. 42:711-725
Mammalian-inducible expression systems are increasingly available and offer an attractive platform for the production of recombinant proteins. In this work, we have conducted process development for a cumate-inducible GS-CHO cell-line-expressing ritu
Autor:
Sven Ansorge, Sean Nesdoly, Amine Kamen, David M. Sharon, Yu Xia, Hsin J. Yang, Jean-François Gélinas
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Cell-derived influenza vaccines provide better protection and a host of other advantages compared to the egg-derived vaccines that currently dominate the market, but their widespread use is hampered by a lack of high yield, low cost production platfo