Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sven, Findeiß"'
Publikováno v:
Non-Coding RNA, Vol 7, Iss 4, p 77 (2021)
Long non-coding RNAs (lncRNAs) are widely recognized as important regulators of gene expression. Their molecular functions range from miRNA sponging to chromatin-associated mechanisms, leading to effects in disease progression and establishing them a
Externí odkaz:
https://doaj.org/article/52a4ac72d7074d2ba1431721f83cc233
Autor:
Christopher Klapproth, Siegfried Zöztsche, Felix Kühnl, Jörg Fallmann, Peter F. Stadler, Sven Findeiß
The in silico prediction of non-coding and protein-coding genetic loci is an area of research that has gathered large attention in the field of comparative genomics. In the last decade, much effort has been made to investigate numerous properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ef900a99754055c056dad55de1e4105
https://doi.org/10.1101/2022.09.01.506220
https://doi.org/10.1101/2022.09.01.506220
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2518
Riboswitches are an attractive target for the directed design of RNA-based regulators by in silico prediction. These noncoding RNA elements consist of an aptamer platform for the highly selective ligand recognition and an expression platform which co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::167a636fd07ba0205cd36da4d19658cc
https://pubmed.ncbi.nlm.nih.gov/35666446
https://pubmed.ncbi.nlm.nih.gov/35666446
Publikováno v:
Riboregulator Design and Analysis ISBN: 9781071624203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::586fbbe10fe03ba192cb0cd4f73fb12c
https://doi.org/10.1007/978-1-0716-2421-0_11
https://doi.org/10.1007/978-1-0716-2421-0_11
Publikováno v:
Sensors, Vol 17, Iss 9, p 1990 (2017)
RNA aptamers readily recognize small organic molecules, polypeptides, as well as other nucleic acids in a highly specific manner. Many such aptamers have evolved as parts of regulatory systems in nature. Experimental selection techniques such as SELE
Externí odkaz:
https://doaj.org/article/2cf4c4f8f8894591a0126c4816bfa464
Publikováno v:
RNA (New York, N.Y.). 28(4)
Removal of the 5′-leader region is an essential step in the maturation of tRNA molecules in all domains of life. This reaction is catalyzed by various RNase P activities, ranging from ribonucleoproteins with ribozyme activity to protein-only forms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876f2c8186333e8af93c59bab7799af4
https://pubmed.ncbi.nlm.nih.gov/35022261
https://pubmed.ncbi.nlm.nih.gov/35022261
Publikováno v:
Nucleic Acids Research
We describe a synthetic riboswitch element that implements a regulatory principle which directly addresses an essential tRNA maturation step. Constructed using a rational in silico design approach, this riboswitch regulates RNase P-catalyzed tRNA 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9029b4124ac04652b566d58bd049b0b4
https://pubmed.ncbi.nlm.nih.gov/33469651
https://pubmed.ncbi.nlm.nih.gov/33469651
Autor:
Peter F. Stadler, Katharina Arnold, Mario Mörl, Sven Findeiß, Christian Günzel, Christina E Weinberg, Felix Kühnl
Publikováno v:
RNA Biol
Gene regulation in prokaryotes often depends on RNA elements such as riboswitches or RNA thermometers located in the 5’ untranslated region of mRNA. Rearrangements of the RNA structure in response, e. g., to the binding of small molecules or ions c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28264085eedcaed79ed3c13160de4535
https://doi.org/10.1101/2020.06.18.159046
https://doi.org/10.1101/2020.06.18.159046
Publikováno v:
Bioinformatics
Motivation Realizing the value of synthetic biology in biotechnology and medicine requires the design of molecules with specialized functions. Due to its close structure to function relationship, and the availability of good structure prediction meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a628ec2690e7e001b353dc0b09a5aace
https://doi.org/10.1093/bioinformatics/btx263
https://doi.org/10.1093/bioinformatics/btx263
Artificial RNA molecules with novel functionality have many applications in synthetic biology, pharmacy and white biotechnology. The de novo design of such devices using computational methods and prediction tools is a resource-efficient alternative t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb131b296c40ad0d06d0a7a5df5afbb
http://arxiv.org/abs/1902.01143
http://arxiv.org/abs/1902.01143