Placental protein 13 (PP13)-induced vasodilation of resistance arteries from pregnant and nonpregnant rats occurs via endothelial-signaling pathways

Autor: Tijana Drobnjak, Sveinbjörn Gizurarson, Natalia I. Gokina, Hamutal Meiri, Maurizio Mandalá, Berthold Huppertz, George Osol

Publikováno v: Hypertension in Pregnancy, Vol 36, Iss 2, Pp 186-195 (2017)

Placental protein 13 (PP13) induces hypotension in rats. This study aims to evaluate PP13 effects on isolated uterine arteries from nonpregnant and mid-pregnant rats. Vessels were isolated, cannulated, and pressurized to 50 mmHg within an arteriograp

Externí odkaz: https://doaj.org/article/bacfdfb7bcd5442ea518c40c81f1f531

Effect of Doxycycline Microencapsulation on Buccal Films: Stability, Mucoadhesion and In Vitro Drug Release

Autor: Venu Gopal Reddy Patlolla, Nikolina Popovic, William Peter Holbrook, Thordis Kristmundsdottir, Sveinbjörn Gizurarson

Publikováno v: Gels, Vol 7, Iss 2, p 51 (2021)

The aim of this work was to stabilize doxycycline in mucoadhesive buccal films at room temperature (25 °C). Since doxycycline is susceptible to degradation such as oxidation and epimerization, tablets are currently the only formulation that can keep

Externí odkaz: https://doaj.org/article/1e109b99c1d944b79e36b18884eb4f13

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Long-term Stabilization of Aqueous Doxycycline Formulations, in Mucoadhesive Hydrogels for Treatment of Oral Mucosal Conditions

Autor: Thordis Kristmundsdottir, Sveinbjörn Gizurarson, W. P. Holbrook, Venu Gopal Reddy Patlolla

Publikováno v: Current Drug Discovery Technologies. 17:376-386

Background: The main aim of this work was to develop stable (>2 years) doxycycline formulation, at clinically relevant concentrations and using clinically relevant formulation. Doxycycline has a MMP- inhibitory effects that is important for the treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fd6e259e40ba8eea89efb2aad0097a
https://doi.org/10.2174/1570163816666190222193902

Modulation of immune responses using adjuvants to facilitate therapeutic vaccination

Autor: Cristina Nativi, Dennis Christensen, Sveinbjörn Gizurarson, Žarko Barjaktarović, Ihsan Gursel, Stephane Paul, Ilias G. Bouzalas, Virgil E.J.C. Schijns, Gabriel K. Pedersen, Ed C. Lavelle, Sergey I. Chernysh, Žiga Jakopin, Jens Brimnes, Ane Ruiz-de-Angulo, Alberto Fernández-Tejada, Camillo Rosano, Bram Slütter, Aneesh Thakur, Maria Lawrenz

Publikováno v: Immunological reviews, 296(1), 169-190
Immunological reviews 296 (2020) 1
Immunological Reviews
Schijns, V, Fernández-tejada, A, Barjaktarović, Ž, Bouzalas, I, Brimnes, J, Chernysh, S, Gizurarson, S, Gursel, I, Jakopin, Ž, Lawrenz, M, Nativi, C, Paul, S, Pedersen, G K, Rosano, C, Ruiz-de-angulo, A, Slütter, B, Thakur, A, Christensen, D & Lavelle, E C 2020, ' Modulation of immune responses using adjuvants to facilitate therapeutic vaccination ', Immunological Reviews, vol. 296, no. 1, pp. 169-190 . https://doi.org/10.1111/imr.12889

Publsher's version (útgefin grein)
Therapeutic vaccination offers great promise as an intervention for a diversity of infectious and non-infectious conditions. Given that most chronic health conditions are thought to have an immune component, v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3824d05f48ada7a932135e42ec4820c6
https://doi.org/10.1111/imr.12889