Zobrazeno 1 - 10
of 344
pro vyhledávání: '"Svati H Shah"'
Autor:
Julia Karady, Robert W McGarrah, Maggie Nguyen, Stephanie N Giamberardino, Nandini Meyersohn, Michael T Lu, Pedro V Staziaki, Stefan B Puchner, Daniel O Bittner, Borek Foldyna, Thomas Mayrhofer, Margery A Connelly, Andre Tchernof, Phillip J White, Khurram Nasir, Kathleen Corey, Deepak Voora, Neha Pagidipati, Geoffrey S Ginsburg, William E Kraus, Udo Hoffmann, Pamela S Douglas, Svati H Shah, Maros Ferencik
Publikováno v:
American Journal of Preventive Cardiology, Vol 18, Iss , Pp 100680- (2024)
Objectives: To determine the relationship between lipoprotein particle size/number with hepatic steatosis (HS), given its association with traditional lipoproteins and coronary atherosclerosis. Methods: Individuals with available CT data and blood sa
Externí odkaz:
https://doaj.org/article/44e227185ee8468e8195c9e37a5c8c32
Autor:
Nathan A Bihlmeyer, Lydia Coulter Kwee, Clary B Clish, Amy Anderson Deik, Robert E Gerszten, Neha J Pagidipati, Blandine Laferrère, Laura P Svetkey, Christopher B Newgard, William E Kraus, Svati H Shah
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0240764 (2021)
Obesity is an epidemic internationally. While weight loss interventions are efficacious, they are compounded by heterogeneity with regards to clinically relevant metabolic responses. Thus, we sought to identify metabolic biomarkers that are associate
Externí odkaz:
https://doaj.org/article/411ee50441d3462a8896a1a30b7353c8
Autor:
Sabina Sayeed, Robert Califf, Robert Green, Celeste Wong, Kenneth Mahaffey, Sanjiv Sam Gambhir, Jessica Mega, Bray Patrick-Lake, Kaylyn Frazier, Michael Pignone, Adrian Hernandez, Svati H Shah, Alice C Fan, Sarah Krüg, Terry Shaack, Scarlet Shore, Susie Spielman, Julie Eckstrand, Charlene A Wong, Project Baseline Health Study Research Group
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254153 (2021)
Newer data platforms offer increased opportunity to share multidimensional health data with research participants, but the preferences of participants for which data to receive and how is evolving. Our objective is to describe the preferences and exp
Externí odkaz:
https://doaj.org/article/a6ce915f4b6f4e77b66b271af01747a5
Autor:
Cavin K Ward-Caviness, Lucas M Neas, Colette Blach, Carol S Haynes, Karen LaRocque-Abramson, Elizabeth Grass, Z Elaine Dowdy, Robert B Devlin, David Diaz-Sanchez, Wayne E Cascio, Marie Lynn Miranda, Simon G Gregory, Svati H Shah, William E Kraus, Elizabeth R Hauser
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173880 (2017)
Air pollution is a worldwide contributor to cardiovascular disease mortality and morbidity. Traffic-related air pollution is a widespread environmental exposure and is associated with multiple cardiovascular outcomes such as coronary atherosclerosis,
Externí odkaz:
https://doaj.org/article/449a19c615f143e8bb8696bfce5e3e69
Autor:
Cavin K Ward-Caviness, Lucas M Neas, Colette Blach, Carol S Haynes, Karen LaRocque-Abramson, Elizabeth Grass, Elaine Dowdy, Robert B Devlin, David Diaz-Sanchez, Wayne E Cascio, Marie Lynn Miranda, Simon G Gregory, Svati H Shah, William E Kraus, Elizabeth R Hauser
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152670 (2016)
There is a growing literature indicating that genetic variants modify many of the associations between environmental exposures and clinical outcomes, potentially by increasing susceptibility to these exposures. However, genome-scale investigations of
Externí odkaz:
https://doaj.org/article/64eba910f3a84c26afa5d774e6b7964b
Autor:
Jennifer R Dungan, Xuejun Qin, Benjamin D Horne, John F Carlquist, Abanish Singh, Melissa Hurdle, Elizabeth Grass, Carol Haynes, Simon G Gregory, Svati H Shah, Elizabeth R Hauser, William E Kraus
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154856 (2016)
Survival bias may unduly impact genetic association with complex diseases; gene-specific survival effects may further complicate such investigations. Coronary artery disease (CAD) is a complex phenotype for which little is understood about gene-speci
Externí odkaz:
https://doaj.org/article/c8a5c97238f14fe0a48da6ba7705c4c1
Autor:
William E Kraus, Deborah M Muoio, Robert Stevens, Damian Craig, James R Bain, Elizabeth Grass, Carol Haynes, Lydia Kwee, Xuejun Qin, Dorothy H Slentz, Deidre Krupp, Michael Muehlbauer, Elizabeth R Hauser, Simon G Gregory, Christopher B Newgard, Svati H Shah
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005553 (2015)
Levels of certain circulating short-chain dicarboxylacylcarnitine (SCDA), long-chain dicarboxylacylcarnitine (LCDA) and medium chain acylcarnitine (MCA) metabolites are heritable and predict cardiovascular disease (CVD) events. Little is known about
Externí odkaz:
https://doaj.org/article/71d65ad2e8ba483ea543b1b239ab3bdc
Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.
Autor:
Ville-Petteri Mäkinen, Mete Civelek, Qingying Meng, Bin Zhang, Jun Zhu, Candace Levian, Tianxiao Huan, Ayellet V Segrè, Sujoy Ghosh, Juan Vivar, Majid Nikpay, Alexandre F R Stewart, Christopher P Nelson, Christina Willenborg, Jeanette Erdmann, Stefan Blakenberg, Christopher J O'Donnell, Winfried März, Reijo Laaksonen, Stephen E Epstein, Sekar Kathiresan, Svati H Shah, Stanley L Hazen, Muredach P Reilly, Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Consortium, Aldons J Lusis, Nilesh J Samani, Heribert Schunkert, Thomas Quertermous, Ruth McPherson, Xia Yang, Themistocles L Assimes
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004502 (2014)
The majority of the heritability of coronary artery disease (CAD) remains unexplained, despite recent successes of genome-wide association studies (GWAS) in identifying novel susceptibility loci. Integrating functional genomic data from a variety of
Externí odkaz:
https://doaj.org/article/80ec6405331e447a8d85afd3605afd24
Autor:
Daniel Nolan, William E Kraus, Elizabeth Hauser, Yi-Ju Li, Dana K Thompson, Jessica Johnson, Hsiang-Cheng Chen, Sarah Nelson, Carol Haynes, Simon G Gregory, Virginia B Kraus, Svati H Shah
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71779 (2013)
Given the importance of cardiovascular disease (CVD) to public health and the demonstrated heritability of both disease status and its related risk factors, identifying the genetic variation underlying these susceptibilities is a critical step in und
Externí odkaz:
https://doaj.org/article/9a7637d26c0546b8ae2e88af9194932a
Autor:
Beverly H Brummett, Michael A Babyak, Rong Jiang, Svati H Shah, Richard C Becker, Carol Haynes, Megan Chryst-Ladd, Damian M Craig, Elizabeth R Hauser, Ilene C Siegler, Cynthia M Kuhn, Abanish Singh, Redford B Williams
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82781 (2013)
Previously we have shown that a functional nonsynonymous single nucleotide polymorphism (rs6318) of the 5HTR2C gene located on the X-chromosome is associated with hypothalamic-pituitary-adrenal axis response to a stress recall task, and with endophen
Externí odkaz:
https://doaj.org/article/6ded6ddb903842019d168073092c9a03